Skip to main content

1-(Morpholinomethyl)naphthalen-2-ol

ADVERTISEMENT
Identification
Molecular formula
C15H17NO2
CAS number
53812-13-4
IUPAC name
1-(morpholinomethyl)naphthalen-2-ol
State
State

At room temperature, 1-(Morpholinomethyl)naphthalen-2-ol is in a solid state. It is typically handled as a solid reagent in chemical processes, often requiring dissolution or further processing for application in different chemical contexts.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.00
Boiling point (Celsius)
450.50
Boiling point (Kelvin)
723.70
General information
Molecular weight
243.31g/mol
Molar mass
243.3050g/mol
Density
1.2740g/cm3
Appearence

1-(Morpholinomethyl)naphthalen-2-ol appears as a solid substance. This compound generally presents itself in a crystalline form, often appearing white or off-white in color, making it visually identifiable as such. The morphology can vary depending on the synthesis method used but is typically fine and powdery.

Comment on solubility

Solubility of 1-(morpholinomethyl)naphthalen-2-ol

The solubility of 1-(morpholinomethyl)naphthalen-2-ol is influenced by various factors, making it an interesting compound for studies in solvation. Here are some key points regarding its solubility:

  • Polarity: The presence of the morpholine group enhances the polarity of the molecule, potentially increasing its solubility in polar solvents.
  • Hydrogen bonding: This compound can engage in hydrogen bonding due to the hydroxyl group present in its structure, which can lead to increased solubility in water and other protic solvents.
  • Solvent interaction: It is expected to be more soluble in solvents that can interact favorably with both the aromatic naphthalene structure and the polar morpholine end, such as alcohols and dimethyl sulfoxide (DMSO).
  • Temperature influences: Like many organic compounds, the solubility of 1-(morpholinomethyl)naphthalen-2-ol is likely to increase with temperature, prompting further exploration for practical applications.

As a result, while 1-(morpholinomethyl)naphthalen-2-ol may demonstrate reasonable solubility in a variety of solvents, the **specific solubility parameters** can vary widely depending on the conditions and the medium used. This makes it essential to investigate solubility under specific experimental setups for accurate predictions.

Interesting facts

Interesting Facts about 1-(Morpholinomethyl)naphthalen-2-ol

1-(Morpholinomethyl)naphthalen-2-ol is a fascinating compound that straddles the line between organic chemistry and medicinal applications. This compound is notable for its unique structure, which combines the elegance of naphthalene with the functional versatility of a morpholine group. Here are some intriguing aspects:

  • Pharmacological Potential: Compounds like 1-(morpholinomethyl)naphthalen-2-ol are often studied for their biological activities, making them of great interest in drug design and development. Researchers are exploring their potential as therapeutic agents.
  • Structure-Activity Relationship (SAR): The presence of the morpholine ring in this compound is particularly intriguing, as it can influence the pharmacokinetic properties and enhance binding affinity to biological targets.
  • Versatile Synthesis: The synthesis of this compound typically involves multi-step organic transformations. It serves as an excellent example of how functional groups can be introduced to modify properties and reactivity.
  • Multifunctionality: The compound exhibits several functional groups, contributing to its potential for varied reactivity. This allows chemists to explore different synthetic pathways and applications.

The exploration of compounds like 1-(morpholinomethyl)naphthalen-2-ol not only enhances our understanding of organic chemistry but also propels advancements in medicinal chemistry. As a compound with hybrid functionality, it stands at the forefront of innovative research, showcasing the endless possibilities within the realm of chemical compounds.

Synonyms
27438-39-7
1-(Morpholin-4-ylmethyl)-2-naphthol
1-(Morpholinomethyl)-2-Naphthol
1-Morpholinomethyl-2-naphthol
2-NAPHTHOL, 1-(MORPHOLINOMETHYL)-
2-Naphthalenol, 1-(4-morpholinylmethyl)-
NSC 89760
EINECS 248-458-2
PJ3W002VVZ
NSC 651417
BRN 0199257
1-(Morpholinomethyl)2-naphthol
NSC-89760
NSC-651417
DTXSID70181855
4-27-00-00175 (Beilstein Handbook Reference)
NSC-109267
1-(4-MORPHOLINYLMETHYL)-2-NAPHTHALENOL
1-(N-MORPHOLINO-4-YLMETHYL)-2-NAPHTHOL
2-((4-MORPHOLINYL)METHYL)-2-NAPHTHALENOL
2-HYDROXY-1-(N-MORPHOLINOMETHYL)NAPHTHALENE
RefChem:428042
DTXCID10104346
2-Naphthalenol, 1-(4-morpholinylmethyl)-(9CI)
1-(morpholinomethyl)naphthalen-2-ol
1-(morpholin-4-ylmethyl)naphthalen-2-ol
1-[(morpholin-4-yl)methyl]naphthalen-2-ol
1-(4-Morpholinylmethyl)-2-naphthol
NSC651417
MFCD00021614
CBMicro_006652
UNII-PJ3W002VVZ
Oprea1_657802
Oprea1_708666
MLS000714133
SCHEMBL6057649
CHEMBL1491673
VNKDDFRRCCZWOU-UHFFFAOYSA-N
HMS1675M05
HMS2762C22
NSC89760
SMSF0005211
AKOS000605775
CB08966
WLN: L66J CQ B1- AT6N DOTJ
NCGC00245463-01
CL-42016
SMR000273613
SY133654
BIM-0006513.P001
DB-047220
CS-0307775
NS00028305
ST50000663
EN300-06939
G34172
Z44101865