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1-[N-(4-piperidyl)phenyl]propan-2-one

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Identification
Molecular formula
C14H20N2O
CAS number
857347-01-4
IUPAC name
1-[N-(4-piperidyl)anilino]propan-2-one
State
State

At room temperature, the compound is typically found in a solid state. It is stable under normal conditions but should be handled with care to avoid exposure to light and moisture. The solid composure makes it easy to handle and measure for analytical purposes.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.15
General information
Molecular weight
219.30g/mol
Molar mass
219.3030g/mol
Density
1.0423g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. The solid form is often utilized in the laboratory setting, characterized by its fine particulate nature. It should be stored in a well-sealed container to prevent moisture absorption.

Comment on solubility

Solubility of 1-[N-(4-piperidyl)anilino]propan-2-one

The solubility of 1-[N-(4-piperidyl)anilino]propan-2-one, a complex organic compound, can be influenced by various factors, including its molecular structure and the nature of the solvent used. Here's what you need to consider:

  • Polar solvents: Due to the presence of both amine and carbonyl functional groups, this compound is expected to have enhanced solubility in polar solvents such as water and ethanol.
  • Non-polar solvents: Conversely, its solubility in non-polar solvents like hexane or toluene may be significantly lower due to lack of adequate intermolecular interactions.
  • pH Dependency: The solubility can be impacted by the pH of the solution, as the amine group may become protonated in acidic conditions, thereby increasing its solubility.
  • Temperature Effects: Increasing the temperature generally enhances solubility for most solids; however, this might vary depending on specific interactions within the compound.

In summary, the solubility of 1-[N-(4-piperidyl)anilino]propan-2-one is a complex interplay of molecular interactions and solvent characteristics. It is highly advisable to conduct solubility tests across various conditions to gauge accurate solubility profiles for practical applications.

Interesting facts

Exploring 1-[N-(4-piperidyl)anilino]propan-2-one

1-[N-(4-piperidyl)anilino]propan-2-one, often referred to as an interesting compound in the realm of organic chemistry, showcases a variety of applications and characteristics that intrigue scientists and students alike. Here are some fascinating facts about this compound:

  • Structural Composition: This compound features a unique structure that combines an aniline derivative with a piperidine ring, which can influence its biological activity and reactivity.
  • Medical Relevance: Compounds that contain piperidine and aniline moieties are often researched for their potential pharmaceutical benefits. This compound may serve as a lead compound in drug discovery processes, particularly in targeting neurological conditions.
  • Versatility in Synthesis: The synthesis of 1-[N-(4-piperidyl)anilino]propan-2-one can be a noteworthy example of amine chemistry, involving nucleophilic substitutions and the ability to manipulate functional groups for desired properties.
  • Research Potential: Given its structure, this compound could be utilized in various research fields, including medicinal chemistry, materials science, and biological pharmacology.
  • Biological Activity: Studies have hinted that similar compounds may exhibit a range of pharmacological activities, such as antipsychotic effects, making them of interest for the development of new treatments.
  • Analytical Techniques: To fully understand 1-[N-(4-piperidyl)anilino]propan-2-one, chemists often employ techniques like NMR spectroscopy, mass spectrometry, and infrared spectroscopy, which help elucidate its chemical environment and bonding characteristics.

In summary, 1-[N-(4-piperidyl)anilino]propan-2-one stands out as a significant compound in organic chemistry, with diverse implications for modern scientific research and potential therapeutic applications. Its intricate structure and associated bioactivity make it a compound worthy of further exploration.