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1-nitro-3-(trifluoromethyl)benzene

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Identification
Molecular formula
C7H4F3NO2
CAS number
402-90-8
IUPAC name
1-nitro-3-(trifluoromethyl)benzene
State
State

This compound is typically a liquid at room temperature.

Melting point (Celsius)
-22.40
Melting point (Kelvin)
250.75
Boiling point (Celsius)
198.00
Boiling point (Kelvin)
471.15
General information
Molecular weight
191.13g/mol
Molar mass
191.1290g/mol
Density
1.4727g/cm3
Appearence

1-nitro-3-(trifluoromethyl)benzene is a pale yellow to amber liquid. It possesses a characteristic aromatic odor typical of other nitroaromatic compounds.

Comment on solubility

Solubility of 1-nitro-3-(trifluoromethyl)benzene

1-nitro-3-(trifluoromethyl)benzene, often referred to as a substituted nitrobenzene, exhibits interesting solubility characteristics due to its unique functional groups. This compound's solubility can be influenced by several factors:

  • Polarity: The presence of both the nitro group (-NO2) and the trifluoromethyl group (-CF3) significantly affects the overall polarity of the molecule, contributing to its solubility profile.
  • Solvent Compatibility: 1-nitro-3-(trifluoromethyl)benzene is known to be better soluble in organic solvents such as:
    • Acetone
    • Toluene
    • Chloroform
  • Limitations in Water: Its solubility in water is considerably low, largely due to the hydrophobic nature of the trifluoromethyl group, which opposes interaction with polar water molecules.

In summary, while 1-nitro-3-(trifluoromethyl)benzene is soluble in various organic solvents, one must exercise caution regarding its interaction with water, as “like dissolves like” often defines solubility trends in chemistry!

Interesting facts

Interesting Facts about 1-Nitro-3-(trifluoromethyl)benzene

1-Nitro-3-(trifluoromethyl)benzene, often referred to as an important aromatic compound, is notable for its distinct chemical properties and applications in various fields of chemistry. Here are some key aspects of this intriguing compound:

  • Structure and Relevance: This compound features a nitro group and a trifluoromethyl group attached to a benzene ring. Its structure enhances its reactivity, making it a valuable intermediate in synthetic organic chemistry.
  • Applications in Synthesis: It is widely used in the production of agrochemicals, pharmaceuticals, and specialty chemicals. The trifluoromethyl group is particularly sought after in drug design for its ability to modify biological activity.
  • Environmental Considerations: As with many nitro compounds, there is a focus on understanding the environmental impact and degradation pathways of 1-nitro-3-(trifluoromethyl)benzene. Its behavior in ecological systems is a vital area of study to mitigate potential adverse effects.
  • Chemical Properties: The presence of both electron-withdrawing groups (the nitro and trifluoromethyl groups) in its molecular structure influences its electrophilic and nucleophilic reactivity, a topic of significant interest for chemists.
  • Research and Innovation: Researchers continue to investigate new methodologies for utilizing 1-nitro-3-(trifluoromethyl)benzene in innovative chemical processes, showcasing its versatility and importance within synthetic chemistry.

In summary, 1-nitro-3-(trifluoromethyl)benzene is not just a compound of interest due to its structural features, but it also plays a crucial role in various chemical applications that impact both industry and research. Its unique properties continue to captivate the attention of chemists looking to push the boundaries of organic synthesis.

Synonyms
3-Nitrobenzotrifluoride
98-46-4
1-Nitro-3-(trifluoromethyl)benzene
m-Nitrobenzotrifluoride
m-Nitrotrifluorotoluene
3-(Trifluoromethyl)nitrobenzene
Benzene, 1-nitro-3-(trifluoromethyl)-
1,3-Nitrobenzotrifluoride
3-Trifluoromethylnitrobenzene
m-Nitrotrifluortoluol
USAF MA-5
M-(TRIFLUOROMETHYL)NITROBENZENE
3-Nitro-alpha,alpha,alpha-trifluorotoluene
NSC 10313
m-Nitrotrifluortoluol [German]
CCRIS 2814
HSDB 4250
alpha,alpha,alpha-Trifluoro-3-nitrotoluene
EINECS 202-670-1
GU6L7C6HW3
alpha,alpha,alpha-Trifluoronitrotoluene
3-Nitro-a,a,a-trifluorotoluene
DTXSID9025794
alpha,alpha,alpha-Trifluoro-m-nitrotoluene
AI3-07485
Toluene, alpha,alpha,alpha-trifluoro-m-nitro-
Toluene, 3-nitro-alpha,alpha,alpha-trifluoro-
NSC-10313
Toluene, .alpha.,.alpha.,.alpha.-trifluoro-m-nitro-
5-NITROBENZOTRIFLUORIDE
DTXCID205794
.alpha.,.alpha.,.alpha.-Trifluoro-3-nitrotoluene
.alpha.,.alpha.,.alpha.-Trifluoro-m-nitrotoluene
Toluene, 3-nitro-.alpha.,.alpha.,.alpha.-trifluoro-
M-(TRIFLUOROMETHYL)NITROBENZENE [HSDB]
.alpha.,.alpha.,.alpha.-Trifluoronitrotoluene
MFCD00007260
M-NITROTRIFLUORTOLUOL (GERMAN)
UNII-GU6L7C6HW3
M-trifluoromethylnitrobenzene
mNitrotrifluortoluol
mNitrobenzotrifluoride
mNitrotrifluorotoluene
3Nitrobenzotrifluoride
3-nitro-trifluorotoluene
WLN: WNR CXFFF
3Trifluoromethylnitrobenzene
UN 2306 (Salt/Mix)
SCHEMBL439710
3-Nitrobenzotrifluoride, 97%
1Nitro3(trifluoromethyl)benzene
CHEMBL1906156
1-trifluoromethyl-3-nitrobenzene
1-nitro-3-trifluoromethyl-benzene
M-NITROFLUOROMETHYL BENZENE
Benzene, 1nitro3(trifluoromethyl)
NSC10313
Tox21_200760
alpha,alpha,alphaTrifluoronitrotoluene
.alpha.,.alpha.-Trifluoronitrotoluene
AKOS003630652
alpha,alpha,alphaTrifluoromnitrotoluene
CAS-98-46-4
NCGC00091713-01
NCGC00091713-02
NCGC00258314-01
Toluene, 3nitroalpha,alpha,alphatrifluoro
Toluene, alpha,alpha,alphatrifluoromnitro
.alpha.,.alpha.-Trifluoro-m-nitrotoluene
AC-10906
AS-12820
m-Nitro-alpha,alpha,alpha-trifluorotoluene
3-(TRIFLUOROMETHYL)-1-NITROBENZENE
3-NITRO-1-(TRIFLUOROMETHYL)BENZENE
A5541
N0280
NS00041241
Toluene,.alpha.,.alpha.-trifluoro-m-nitro-
EN300-207713
3-Nitro-.alpha.,.alpha.,.alpha.-trifluorotoluene
m-Nitro-.alpha.,.alpha.,.alpha.-trifluorotoluene
Toluene, alpha,alpha,alpha-trifluoro-m-nitro-(8CI)
Q27279290
1,3,5-trifluoro-2-methyl-4-nitrobenzene;3-Nitrobenzotrifluoride
3-Nitro-alpha,alpha,alpha-trifluorotoluene, 3-(Trifluoromethyl)nitrobenzene
1-Nitro-3-(trifluoromethyl)benzene; 3-Nitro-alpha,alpha,alpha-trifluorotoluene; alpha,alpha,alpha-Trifluoro-3-nitrotoluene
202-670-1