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1-Nitro-4-(trifluoromethyl)benzene

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Identification
Molecular formula
C7H4F3NO2
CAS number
299-88-7
IUPAC name
1-nitro-4-(trifluoromethyl)benzene
State
State

Solid

At room temperature, it is typically found in solid form, exhibiting a crystalline structure.

Melting point (Celsius)
44.00
Melting point (Kelvin)
317.15
Boiling point (Celsius)
232.70
Boiling point (Kelvin)
505.85
General information
Molecular weight
205.11g/mol
Molar mass
205.1290g/mol
Density
1.4120g/cm3
Appearence

1-Nitro-4-(trifluoromethyl)benzene appears as a pale yellow solid. It is an aromatic compound with a crystalline structure.

Comment on solubility

Solubility of 1-nitro-4-(trifluoromethyl)benzene

1-nitro-4-(trifluoromethyl)benzene, with its unique molecular structure, exhibits particular solubility characteristics that are influenced by its functional groups. This compound is predominantly non-polar due to the significant presence of the trifluoromethyl group, which imparts hydrophobic properties.

Here are some key points regarding its solubility:

  • In organic solvents: 1-nitro-4-(trifluoromethyl)benzene demonstrates good solubility in non-polar organic solvents such as hexane or toluene.
  • In water: This compound is sparingly soluble in water due to its hydrophobic nature and the limited ability to form hydrogen bonds.
  • Effect of temperature: Solubility in organic solvents tends to increase with temperature, making it more feasible for applications requiring a higher thermal environment.

As a result, while 1-nitro-4-(trifluoromethyl)benzene may not readily dissolve in water, its compatibility with various organic solvents opens up avenues for diverse applications in chemical synthesis and material science.

Interesting facts

Interesting Facts About 1-Nitro-4-(trifluoromethyl)benzene

1-Nitro-4-(trifluoromethyl)benzene, often referred to as a derivative of nitrobenzene, is a fascinating compound that showcases the intriguing world of organic chemistry. It carries significant implications in both research and industrial applications.

Chemical Significance

  • Substituted Aromatic Compound: This compound is notable for its substitution pattern on the benzene ring, where a nitro group and a trifluoromethyl group are both present, influencing its reactivity and electronic properties.
  • Electrophilic Aromatic Substitution: The presence of the nitro group makes this compound a good candidate for further substitution reactions, as it is a strong electron-withdrawing group that can enhance electrophilicity.

Applications

  • Pharmaceutical Synthesis: Compounds like 1-nitro-4-(trifluoromethyl)benzene are often utilized as intermediates in the synthesis of various pharmaceuticals and agrochemicals.
  • Material Science: This compound may be explored for potential applications in creating advanced materials due to the unique properties conferred by the trifluoromethyl group, which can provide thermal stability and chemical resistance.

Properties and Behaviors

When studying 1-nitro-4-(trifluoromethyl)benzene, one can observe:

  • Hydrophobic Nature: The trifluoromethyl group contributes to its low solubility in water, making it relevant for research in environmental chemistry, particularly in assessing the behavior of contaminants.
  • Reactivity Patterns: The unique combination of functional groups allows chemists to predict and manipulate its reactivity, guiding pathways for designing new chemical entities.

In summary, 1-nitro-4-(trifluoromethyl)benzene is more than just a simple compound; it is a gateway to exploring the complex interplay of substituents within organic chemistry. As scientists continue to delve into its properties and potential applications, it stands as a testament to the innovative spirit of the field.

Synonyms
4-Nitrobenzotrifluoride
402-54-0
1-Nitro-4-(trifluoromethyl)benzene
p-Nitrobenzotrifluoride
Benzene, 1-nitro-4-(trifluoromethyl)-
4-(TRIFLUOROMETHYL)NITROBENZENE
4-Nitro-alpha,alpha,alpha-trifluorotoluene
4-NITRO-A,A,A-TRIFLUOROTOLUENE
p-Nitro(trifluoromethyl)benzene
NSC 159121
4-nitro-1-(trifluoromethyl)benzene
NSC-159121
ALPHA,ALPHA,ALPHA-TRIFLUORO-P-NITROTOLUENE
4-Nitro-.alpha.,.alpha.,.alpha.-trifluorotoluene
MFCD00007358
p-nitro-Trifluoromethylphenol
EINECS 206-948-3
4-nitrobenzotrifluorid
4-(TRIFLUOROMETHYL)-1-NITROBENZENE
N47TT2JQ3Y
SCHEMBL439543
4-Nitrobenzotrifluoride, 98%
DTXSID0075281
1-Nitro-4-trifluoromethyl-benzene
1-nitro-4-(trifluoromethyl)-benzene
NSC159121
AKOS015889713
P-(TRIFLUOROMETHYL)NITROBENZENE
AC-4147
CS-W015852
FN97995
AS-16062
A1677
N0902
NS00043263
Toluene, 4-nitro-.alpha.,.alpha.,.alpha.-trifluoro-
TOLUENE, ALPHA,ALPHA,ALPHA-TRIFLUORO-P-NITRO-
Z56762338
4-Nitro-alpha,alpha,alpha-trifluorotoluene;4-(trifluoromethyl)nitrobenzene