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1-Nitroso-1-phenylurea

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Identification
Molecular formula
C7H7N3O2
CAS number
156-10-5
IUPAC name
1-nitroso-1-phenyl-urea
State
State

At room temperature, 1-nitroso-1-phenylurea is typically found in a solid state. It is stable under normal conditions but should be kept in a tightly sealed container to prevent deterioration.

Melting point (Celsius)
147.50
Melting point (Kelvin)
420.65
Boiling point (Celsius)
351.00
Boiling point (Kelvin)
624.15
General information
Molecular weight
151.14g/mol
Molar mass
151.1410g/mol
Density
1.3299g/cm3
Appearence

1-Nitroso-1-phenylurea appears as a solid crystalline substance. It typically presents in pale yellow to light brown colors. Proper handling and storage conditions are necessary to maintain its appearance, as exposure to moisture or air might affect its state.

Comment on solubility

Solubility of 1-nitroso-1-phenyl-urea

When considering the solubility of 1-nitroso-1-phenyl-urea, it is essential to note several key factors that influence its behavior in various solvents:

  • Polarity: The presence of both a nitroso group and the urea functionality contributes to the overall polarity of the molecule, which can enhance its solubility in polar solvents.
  • Solvent Compatibility: 1-nitroso-1-phenyl-urea is generally more soluble in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol compared to non-polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can significantly increase solubility. Urea compounds are known to engage in strong hydrogen bonding interactions.
  • Temperature Effects: Like many organic compounds, the solubility of 1-nitroso-1-phenyl-urea can be increased with rising temperatures, as increased kinetic energy often helps overcome solvation barriers.

Overall, while 1-nitroso-1-phenyl-urea exhibits limited solubility in water due to its organic nature, its compatibility with various polar solvents and the potential for hydrogen bonding make it a versatile compound in a range of chemical applications. As with many organic nitrogen compounds, understanding and manipulating solubility can play a crucial role in their practical utility.

Interesting facts

Interesting Facts about 1-nitroso-1-phenyl-urea

1-nitroso-1-phenyl-urea is a fascinating chemical compound known for its unique structure and properties. This compound incorporates both a nitroso functional group and a phenyl group, making it an intriguing subject of study in the field of organic chemistry. Here are some interesting points about it:

  • Chemical Structure: The presence of the nitroso group (–N=O) attached to a carbon atom that also bears a phenyl group provides a rich platform for various chemical reactions.
  • Applications: 1-nitroso-1-phenyl-urea has been explored in medicinal chemistry for its potential applications in drug design, particularly in compounds that exhibit antimicrobial properties.
  • Reactivity: This compound is known for its electrophilic characteristics, which can make it a useful intermediate in organic synthesis.
  • Research Interest: The compound has garnered attention in studies focused on nitrogen-containing organic molecules, contributing to the understanding of reactivity patterns in similar compounds.

As an example of nitrogen chemistry, 1-nitroso-1-phenyl-urea helps illustrate how modifying a urea structure can lead to significant shifts in reactivity and application. Scientists continue to investigate its properties, hoping to unlock potential new applications and improve our understanding of nitroso compounds in general.

Synonyms
1-nitroso-1-phenylurea
UREA, N-NITROSO-N-PHENYL-
Urea, 1-nitroso-1-phenyl-
6268-32-2
EI3CV902WD
NSC-36238
NSC 36238
BRN 1841800
N-nitrosophenylurea
NSC36238
UNII-EI3CV902WD
N-NITROSO-N-PHENYLUREA
SCHEMBL1096892
DTXSID00211735
AKOS006276786