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1-Nitrosopiperidine

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Identification
Molecular formula
C5H10N2O
CAS number
100-75-4
IUPAC name
1-nitrosopiperidine
State
State
At room temperature, 1-Nitrosopiperidine exists as a liquid. It is characterized by its high volatility and sensitivity to light.
Melting point (Celsius)
-11.00
Melting point (Kelvin)
262.15
Boiling point (Celsius)
82.00
Boiling point (Kelvin)
355.15
General information
Molecular weight
114.15g/mol
Molar mass
114.1540g/mol
Density
1.0090g/cm3
Appearence

1-Nitrosopiperidine typically appears as a yellow, oily liquid. It is known to be sensitive to light and may darken upon exposure. The compound may also exhibit a distinct, pungent odor.

Comment on solubility

Solubility of 1-nitrosopiperidine

1-nitrosopiperidine, with the chemical formula C5H10N2O, exhibits intriguing solubility characteristics that are noteworthy for various applications.

This compound generally demonstrates:

  • High solubility in organic solvents: 1-nitrosopiperidine readily dissolves in non-polar solvents such as hexane and ethyl acetate. This property is beneficial in organic synthesis and extracting procedures.
  • Limited solubility in water: Due to its hydrophobic piperidine ring, the solubility of 1-nitrosopiperidine in water is quite low, which may hinder its use in aqueous-based systems.
  • Effect of temperature: The solubility can increase with temperature, following the typical trend where the dissolution of many organic substances is facilitated by heating.

Understanding the solubility of 1-nitrosopiperidine is essential for safe handling and effective application in chemical processes. As highlighted, its tendency to dissolve well in organic media while being poorly soluble in water emphasizes the unique interactions this compound undergoes with various solvents.

In conclusion, the solubility profile of 1-nitrosopiperidine is a critical aspect that influences its practical utility in laboratory and industrial settings.

Interesting facts

Interesting Facts about 1-Nitrosopiperidine

1-Nitrosopiperidine is a fascinating chemical compound that draws interest from both chemists and students alike. As a derivative of piperidine, it features a nitroso group that significantly alters its chemical behavior and properties.

Key Features

  • Reactivity: The presence of the nitroso functional group makes 1-nitrosopiperidine a reactive species, engaging in various chemical reactions typical for nitroso compounds.
  • Health Concerns: This compound is noteworthy for its potential as a nitrosamine. Nitrosamines are known carcinogens, making the study of compounds like 1-nitrosopiperidine important in toxological research.
  • Synthetic Applications: It is often used in organic synthesis and as an intermediate in chemical reactions, showcasing its utility in producing more complex molecules.
  • Research Interest: The compound has gained attention in the research community for exploring mechanisms of action, particularly in the context of carcinogenicity, which raises critical public health issues.

Quotes & Perspectives

As one scientist put it, "Understanding compounds like 1-nitrosopiperidine not only unveils the nature of chemical reactions but also helps us recognize their implications in medicine and health.”

Additionally, students studying this compound often reflect on the duality of its usefulness as a synthetic intermediate and its associated risks, emphasizing the importance of responsible chemistry.

Final Thoughts

In summary, 1-nitrosopiperidine is not just another chemical in the lab; it embodies a rich intersection of chemistry, health, and safety that stimulates ongoing research and discussion among chemists and students alike.

Synonyms
N-NITROSOPIPERIDINE
1-Nitrosopiperidine
100-75-4
Piperidine, 1-nitroso-
Nitrosopiperidin
NO-Pip
NPIP
N-Nitroso-piperidin
nitrosopiperidine
N-PIP
RCRA waste number U179
NSC 138
CCRIS 477
Pyridine, hexahydro-N-nitroso-
HSDB 5115
EINECS 202-886-6
UNII-6N066XUL4L
TL 266
BRN 0110253
1-Nitroso-piperidine
6N066XUL4L
DTXSID8021060
CHEBI:76324
Piperidine,1-nitroso-
NSC-138
N-nitrosohexahydropyridine
N-Nitrosopiperidine-d4
NITROSOPIPERIDINE, N-
DTXCID901060
NSC138
N-NITROSOPIPERIDINE [HSDB]
N-NITROSOPIPERIDINE [IARC]
5-20-03-00530 (Beilstein Handbook Reference)
N-NITROSOPIPERIDINE (IARC)
Nitrosopiperidin [German]
N-Nitroso-piperidin [German]
N-N-Pip
RCRA waste no. U179
N-nitrosopentamethyleneimine
1-Nitrosopiperidine solution
pyridine,hexahydro-N-nitroso
NNitrosopiperidin
1Nitrosopiperidine
NOPip
Piperidine, 1-nitroso-; 1-Nitrosopiperidine; N-Nitrosopiperidine; NPI; NPIP; NSC 138
Piperidine, 1nitroso
WLN: T6NTJ ANO
Pyridine, hexahydroNnitroso
Hexahydro-N-nitroso-pyridine
MLS002152912
Pyridine, hexahydro-N-nitroso
SCHEMBL605035
1-Nitrosopiperidine;NPI;NPIP
CHEMBL165244
HMS3039N10
KNB04921
Tox21_200267
AKOS006275616
FN26386
NCGC00091386-01
NCGC00091386-02
NCGC00257821-01
AS-76660
CAS-100-75-4
SMR001224515
NS00000639
N-Nitrosopiperidine 10 microg/mL in Methanol
C19284
D92816
EN300-7215701
Q22138417
Z1198147906