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1-nitrosopiperidine-2-carboxylic acid

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Identification
Molecular formula
C6H10N2O3
CAS number
37829-16-2
IUPAC name
1-nitrosopiperidine-2-carboxylic acid
State
State

At room temperature, 1-nitrosopiperidine-2-carboxylic acid exists as a solid. It is stable under normal conditions of use and storage.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
172.17g/mol
Molar mass
172.1690g/mol
Density
1.3040g/cm3
Appearence

1-Nitrosopiperidine-2-carboxylic acid often appears as a crystalline solid. The crystals are typically colorless or pale yellow.

Comment on solubility

Solubility of 1-Nitrosopiperidine-2-carboxylic Acid

The solubility of 1-nitrosopiperidine-2-carboxylic acid can be described as follows:

  • Water Solubility: This compound exhibits a moderate level of solubility in water due to its polar carboxylic acid group. The presence of the nitroso group also contributes to its solubility characteristics.
  • Organic Solvents: It tends to be more soluble in polar organic solvents such as alcohols and dimethyl sulfoxide (DMSO), enhancing its applicability in various chemical reactions.
  • pH Dependence: The solubility can also be affected by the pH of the solution; in more acidic environments, the carboxylic acid group may remain protonated, impacting solubility.

To summarize, 1-nitrosopiperidine-2-carboxylic acid is relatively soluble in water and polar organic solvents, making it useful in both synthetic processes and as a biochemical reagent. Its solubility properties can shift depending on environmental conditions, underlining the importance of considering pH and solvent polarity when working with this compound.

Interesting facts

Interesting Facts About 1-Nitrosopiperidine-2-Carboxylic Acid

1-Nitrosopiperidine-2-carboxylic acid is a fascinating compound with various noteworthy aspects, particularly in the realms of synthetic organic chemistry and biological research. Here are some interesting facts:

  • Structure and Properties: As an amino acid derivative, 1-nitrosopiperidine-2-carboxylic acid features both a nitroso group and a carboxylic acid group, contributing to its unique reactivity. The structural complexity allows it to participate in various chemical transformations.
  • Biological Significance: Compounds with nitroso groups are known for their role in biochemistry. They can act as signaling molecules or can exhibit *antiradical* properties, making them of interest in studying oxidative stress and related diseases.
  • Applications in Synthesis: This compound serves as an important intermediate in the synthesis of pharmaceuticals and agrochemicals. It can be employed in reactions that create complex molecules, making it valuable for medicinal chemistry.
  • Safety Precautions: As with many nitroso compounds, working with 1-nitrosopiperidine-2-carboxylic acid requires caution due to its potential health risks. It has been associated with carcinogenic properties, which underscores the importance of handling it with care in the laboratory.
  • Research Potential: Ongoing research is aimed at elucidating the full range of its biological activities and potential therapeutic effects. The compound serves as a great example of how nitroso compounds can impact the fields of pharmacology and toxicology.

In summary, 1-nitrosopiperidine-2-carboxylic acid not only showcases the intricate dance of organic chemistry but also illustrates the interplay between chemical structure and biological function. As scientists continue to explore its capabilities, it promises to unveil more secrets that could have significant implications in health and disease.

Synonyms
4515-18-8
N-Nitrosopipecolic acid
2-Piperidinecarboxylic acid, 1-nitroso-
1-Nitrosopipecolic acid
Nitrosopipecolic acid
PIPECOLIC ACID, 1-NITROSO-
N-Nitrosopipecolinic acid
UNII-GT0I550TQK
GT0I550TQK
NSC 109550
BRN 0135674
NSC-109550
DTXSID4021058
5-22-01-00235 (Beilstein Handbook Reference)
30310-81-7
1Nitrosopipecolic acid
Pipecolic acid, 1nitroso
DTXCID801058
1Nitrosopiperidine2carboxylic acid
2Piperidinecarboxylic acid, 1nitroso
dsgktuvitpqprt-uhfffaoysa-n
1-nitrosopiperidine-2-carboxylic acid
N-Nitroso-D,L-pipecolic Acid
1-Nitroso-2-piperidinecarboxylic acid
CHEMBL75711
1-Nitroso-2-piperidinecarboxylic acid #
NPIPAC; N-Nitrosopiperidine-2-carboxylic Acid; 1-Nitroso-2-piperidinecarboxylic Acid; 1-Nitrosopipecolic Acid; NSC 109550;
MFCD01704295
SCHEMBL2928932
BDBM50403317
NSC109550
AKOS006277089
AT40229
SY205290
1-NITROSOPIPERIDINE-2-CARBOXYLICACID
DB-329007
(2RS)-1-nitrosopiperidine-2-carboxylic acid
EN300-244257
Q27279267
Z1198157894