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1-Nitrosopyrrolidine

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Identification
Molecular formula
C4H8N2O
CAS number
930-55-2
IUPAC name
1-nitrosopyrrolidine
State
State

At room temperature, 1-Nitrosopyrrolidine is found in a liquid state. It is often described as an oily substance which indicates that it does not solidify easily under standard conditions, staying as a liquid at most ambient temperatures.

Melting point (Celsius)
-41.00
Melting point (Kelvin)
232.15
Boiling point (Celsius)
216.00
Boiling point (Kelvin)
489.15
General information
Molecular weight
100.13g/mol
Molar mass
100.1290g/mol
Density
1.1360g/cm3
Appearence

1-Nitrosopyrrolidine is a yellow oily liquid. It typically appears as a pale yellow oil that is hygroscopic in nature. The compound can darken upon exposure to air and light, a common characteristic of nitrosamines.

Comment on solubility

Solubility of 1-Nitrosopyrrolidine

1-Nitrosopyrrolidine exhibits distinct solubility characteristics that are important to consider when working with this compound. Its solubility can be summarized as follows:

  • Water Solubility: 1-nitrosopyrrolidine has moderate solubility in water, which is indicative of its polar nature.
  • Organic Solvents: It is soluble in various organic solvents such as ethanol, methanol, and acetone, allowing for diverse applications in organic chemistry.
  • Temperature Dependence: The solubility tends to increase with temperature, which is typical for most organic compounds.

In practical terms, this solubility behavior means that 1-nitrosopyrrolidine can be effectively utilized in biochemical experiments, affording easy handling and manipulation in both aqueous and organic environments. As with any chemical, precautions should be taken, especially considering the implications of its solubility for stability and reactivity in different mediums.

Interesting facts

Interesting Facts About 1-Nitrosopyrrolidine

1-Nitrosopyrrolidine is a fascinating compound that garnered attention for its unique chemical structure and properties. Here are some intriguing aspects of this compound:

  • Origin and Applications: 1-Nitrosopyrrolidine is often studied in the context of organic chemistry and materials science. It is primarily used as a reagent and is considered important in the field of nitrosation reactions.
  • Biological Implications: This compound has attracted interest for its potential role in biological systems. As a nitroso compound, it can act as a signaling molecule in some biological pathways, which is an area of ongoing research.
  • Toxicological Studies: Researchers have conducted numerous studies on the toxicity and mutagenicity of 1-nitrosopyrrolidine. It has been linked to the formation of nitrosamines, many of which are known for their carcinogenic properties, raising important health considerations.
  • Synthesis Techniques: The synthesis of 1-nitrosopyrrolidine can be performed through several methodologies, typically involving the reaction of pyrrolidine with nitrous acid, illustrating practical applications of nitrosation in synthetic organic chemistry.

As quoted by a prominent chemist, "Chemical substances like 1-nitrosopyrrolidine serve not only as building blocks in synthesis but also as keys to understanding complex biological interactions." This highlights the dual nature of many compounds, acting as both tools and subjects of investigation in scientific research.

In summary, 1-nitrosopyrrolidine is much more than a simple chemical entity; it occupies a crucial role in various research fields, from synthetic chemistry to toxicology. Its diverse applications and significance make it a compound worthy of study.

Synonyms
1-Nitrosopyrrolidine
N-NITROSOPYRROLIDINE
930-55-2
Pyrrolidine, 1-nitroso-
Nitrosopyrrolidine
1-nitroso-Pyrrolidine
N-PYR
RCRA waste number U180
CCRIS 478
NSC 18797
Pyrrole, tetrahydro-N-nitroso-
HSDB 5116
EINECS 213-218-8
N-Nitrosopyrrolidine (NPYR)
BRN 0107615
SZ4J5WK201
DTXSID8021062
AI3-62030
NSC-18797
Tetrahydro-N-nitroso-Pyrrole
DTXCID701062
N-NITROSOPYRROLIDINE [MI]
N-NITROSOPYRROLIDINE [HSDB]
N-NITROSOPYRROLIDINE [IARC]
5-20-01-00521 (Beilstein Handbook Reference)
NSC18797
N-NITROSOPYRROLIDINE (IARC)
N Nitrosopyrrolidine
N-N-PYR
NNitrosopyrrolidin
1Nitrosopyrrolidine
NOPYR
Pyrrolidine, 1nitroso
1Pyrrolidinamine, Nnitroso
Pyrrole, tetrahydroNnitroso
inchi=1/c4h8n2o/c7-5-6-3-1-2-4-6/h1-4h
wnyadzvdbibljj-uhfffaoysa-n
NPYR
No-pyr
N-Nitrosopyrrolidin
1-Pyrrolidinamine, N-nitroso-
N-Nitroso-pyrrolidine
CHEBI:82362
35884-45-8
CAS-930-55-2
N-Nitrosopyrrolidin [German]
Pyrrolidine, nitroso-
RCRA waste no. U180
UNII-SZ4J5WK201
Pyrrolidine, 1-nitroso-; 1-Nitrosopyrrolidine; N-Nitrosopyrrolidine; NPYR; NSC 18797
Nitroso-Pyrrolidine
WLN: T5NTJ ANO
1-Nitrosopyrrolidine, 99%
N-Nitroso-1-Pyrrolidinamine
SCHEMBL606668
CHEMBL351175
NPYR;NSC 18797
Tox21_202356
Tox21_302913
MFCD00003166
MSK4908-100M
AKOS006227868
MSK4908-1000M
FN26387
HY-W141077
NCGC00249214-01
NCGC00256421-01
NCGC00259905-01
BS-17894
SY115826
DB-057363
NS00010284
C19285
D82025
N-Nitrosopyrrolidine 10 microg/mL in Methanol
N-Nitrosopyrrolidine 100 microg/mL in Methanol
EN300-1296527
N-Nitrosopyrrolidine Solution in Methanol, 100_g/mL
N-Nitrosopyrrolidine Solution in Methanol, 1000_g/mL
Q22138421