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Picolinic acid N-oxide

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Identification
Molecular formula
C6H5NO3
CAS number
3731-51-9
IUPAC name
1-oxidopyridin-1-ium-3-carboxylic acid
State
State

At room temperature, picolinic acid N-oxide is in a solid state. It is a stable compound that does not easily transition into other states of matter under normal conditions.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
324.00
Boiling point (Kelvin)
597.15
General information
Molecular weight
139.11g/mol
Molar mass
139.1080g/mol
Density
1.5600g/cm3
Appearence

Picolinic acid N-oxide typically appears as a white to off-white crystalline powder. It is known for its crystalline structure which is common among many carboxylic acid derivatives. The compound is stable under standard conditions and has an appearance that is devoid of any significant coloration, indicating its purity.

Comment on solubility

Solubility of 1-oxidopyridin-1-ium-3-carboxylic acid

1-oxidopyridin-1-ium-3-carboxylic acid, also referred to as (1-hydroxypyridin-1-ium-3-carboxylate), exhibits interesting solubility properties that warrant exploration. Its solubility is influenced by several factors including:

  • Polarity: The presence of the carboxylic acid group contributes to overall polarity, enhancing solubility in polar solvents.
  • Ionization: In aqueous solutions, this compound can ionize, forming anions that greatly increase solubility, particularly in water.
  • Temperature: Like many other compounds, solubility may increase with an increase in temperature, allowing for greater interaction with the solvent molecules.
  • Solvent Type: Solubility is notably high in polar solvents such as water and alcohols, while it may be limited in non-polar organic solvents.

In summary, 1-oxidopyridin-1-ium-3-carboxylic acid demonstrates good water solubility largely due to its ionic nature and the presence of polar functional groups. As stated, "the ionized form of the acid is more soluble than its neutral counterpart," which highlights the importance of its acidic properties in solubility. Understanding these characteristics is essential for applications in various fields, particularly in pharmaceuticals and materials science.

Interesting facts

Interesting Facts About 1-Oxidopyridin-1-ium-3-carboxylic Acid

1-Oxidopyridin-1-ium-3-carboxylic acid, often referred to in shorthand as its experimental name, is a fascinating compound that garners interest in both organic chemistry and pharmaceutical sciences. Below are some noteworthy aspects of this intriguing compound:

  • Functional Group Diversity: The compound contains both carboxylic acid and a pyridinium ion, showcasing a rich functional group diversity. This dual functionality opens avenues for various chemical reactions and applications.
  • Biological Activity: Compounds similar to 1-oxidopyridin-1-ium-3-carboxylic acid are often evaluated for biological properties, including anti-inflammatory and antimicrobial effects. Their structural features hint at potential pharmacological benefits.
  • Synthesis: The synthesis of this compound can serve as an intriguing demonstration of organic synthesis techniques, especially in illustrating how different functional groups can be introduced in a stepwise fashion during laboratory experiments.
  • Applications in Coordination Chemistry: Being a nitrogen-containing heterocycle, 1-oxidopyridin-1-ium-3-carboxylic acid can form complexes with transition metals, making it valuable in coordination chemistry for developing catalysts and materials.

As a compound that bridges several fields of chemistry, 1-oxidopyridin-1-ium-3-carboxylic acid serves as an engaging subject for advanced study and highlights the importance of functional group exploration in understanding molecular interactions and potential applications. Whether you are a student or a seasoned scientist, diving into the chemistry of such compounds enhances our comprehension of both fundamental and applied chemistry.

Synonyms
Nicotinic acid N-oxide
2398-81-4
Oxiniacic acid
Nicotinic acid 1-oxide
3-Pyridinecarboxylic acid, 1-oxide
Nicotinic acid oxide
Acido oxiniacico
Acide oxiniacique
N-Hydroxynicotinic acid
3-Carboxypyridine N-oxide
Acidum oxiniacicum
3-Pyridinecarboxylic acid oxide
Pyridine-3-carboxylic acid N-oxide
Oxiniacic acid [INN:DCF]
NSC-93890
YY03Q39E6L
Acide oxiniacique [INN-French]
Acido oxiniacico [INN-Spanish]
Acidum oxiniacicum [INN-Latin]
DTXSID2046543
EINECS 219-265-0
NSC 93890
OXINIACIC ACID [MI]
OXINIACIC ACID [INN]
DTXCID0026543
EC 219-265-0
Acide oxiniacique (INN-French)
Acido oxiniacico (INN-Spanish)
Acidum oxiniacicum (INN-Latin)
3-Pyridinecarboxylic acid 1-oxide
219-265-0
3-Carboxypyridine 1-oxide
1-oxidopyridin-1-ium-3-carboxylic acid
pyridine-3-carboxylic acid 1-oxide
Nicotinic acid, 1-oxide
MFCD00006201
3-carboxypyridin-1-ium-1-olate
NCGC00166106-01
NicotinicacidN-oxide
NICOTINIC ACID-N-OXIDE
CAS-2398-81-4
UNII-YY03Q39E6L
oxiniacic-acid
1-Oxidopyridin-1-ium-3-carboxylic Acid; 3-Carboxypyridine 1-Oxide;
Nicotinic acid, N-oxide
3-Pyridylcarboxylate N-oxide
SCHEMBL129209
Nicotinic acid N-oxide, 99%
CHEMBL1591725
pyridine, 1-oxide, 3-carboxy-
3-Pyridinecarboxylic acid N-oxide
CHEBI:134763
FJCFFCXMEXZEIM-UHFFFAOYSA-N
HMS3264A16
Pharmakon1600-01506168
BCP32247
NSC93890
Tox21_112319
AC8656
BBL012227
BDBM50427220
NSC760387
STK012697
AKOS000120397
Tox21_112319_1
CCG-214004
NSC-760387
NCGC00166106-03
SY112140
DB-046311
N0497
NS00027528
EN300-20386
AB01563244_01
AJ-333/25022123
SR-01000944277
SR-01000944277-1
BRD-K20417253-001-01-9
Q27294770
F2191-0174
Z104477974
Oxiniacic acid;Nicotinic acid 1-oxide;3-Carboxypyridine 1-oxide