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3-hydroxypyridine 1-oxide

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Identification
Molecular formula
C5H5NO2
CAS number
109-00-2
IUPAC name
1-oxidopyridin-1-ium-3-ol
State
State

At room temperature, 3-hydroxypyridine 1-oxide is typically a solid.

Melting point (Celsius)
124.00
Melting point (Kelvin)
397.15
Boiling point (Celsius)
288.00
Boiling point (Kelvin)
561.15
General information
Molecular weight
111.10g/mol
Molar mass
111.0980g/mol
Density
1.2790g/cm3
Appearence

3-Hydroxypyridine 1-oxide typically appears as a crystalline solid. The crystals are often white or off-white in color, and the compound is generally stable under normal conditions of use and storage.

Comment on solubility

Solubility of 1-oxidopyridin-1-ium-3-ol

The solubility of 1-oxidopyridin-1-ium-3-ol is an intriguing topic due to its unique properties as a heterocyclic compound. Generally, the solubility of such compounds can be influenced by a variety of factors:

  • Polarity: The presence of polar functional groups often enhances solubility in polar solvents, such as water.
  • Hydrogen bonding: The ability of 1-oxidopyridin-1-ium-3-ol to engage in hydrogen bonding may increase its interaction with solvents, thus affecting overall solubility.
  • Ionization: As a compound that can exhibit ionization, the solubility is expected to vary significantly with pH levels.

In general, 1-oxidopyridin-1-ium-3-ol is known to be soluble in polar solvents, particularly due to the hydrophilic nature of its functional groups. This solubility makes it particularly interesting for applications in biological and chemical processes.

Furthermore, it is essential to consider that the solubility may change with temperature, and concentration effects can also play a significant role. As the temperature increases, solubility tends to enhance due to greater kinetic energy disrupting solvated structures.

In summary, the solubility of 1-oxidopyridin-1-ium-3-ol is multifaceted and can be succinctly described by the following key points:

  1. Influence of polarity and functional groups
  2. Hydrogen bonding capabilities
  3. Impact of pH and temperature

In conclusion, the solubility of 1-oxidopyridin-1-ium-3-ol is favorable in polar environments, providing a versatile compound for various chemical applications.

Interesting facts

Interesting Facts about 1-Oxidopyridin-1-ium-3-ol

1-Oxidopyridin-1-ium-3-ol, often abbreviated as a pyridinium compound, is a fascinating member of the pyridine family that showcases unique structural and functional properties.

Chemical Structure and Properties

  • Ionic Nature: The presence of a positively charged nitrogen atom gives this compound its ionic characteristics, making it a notable participant in various chemical reactions.
  • Protonated Form: As a pyridinium ion, it plays a significant role in proton transfer reactions, influencing acid-base chemistry.
  • Functional Group: The hydroxyl group in its structure contributes to its reactivity, providing opportunities for further chemical transformations.

Applications in Chemistry

  1. Catalysis: 1-Oxidopyridin-1-ium-3-ol serves as a catalyst in several organic reactions, demonstrating its efficiency in facilitating chemical transformations.
  2. Pharmaceutical Research: This compound has potential applications in medicinal chemistry, particularly for drug design and development due to its ability to interact with biological systems.
  3. Electrochemistry: Its unique redox properties make it a valuable compound for studies in electrochemistry, allowing scientists to explore its behavior in different environments.

Biological Significance

The biological relevance of 1-oxidopyridin-1-ium-3-ol is noteworthy, as compounds with similar structures are often explored for their pharmacological properties. Preliminary studies suggest that it may exhibit antimicrobial and antiviral activities, making it a candidate for future therapeutic applications.

In conclusion, 1-oxidopyridin-1-ium-3-ol is more than just a chemical compound; it is a versatile member of the pyridine family with diverse applications, captivating the interest of chemists and pharmacologists alike.

Synonyms
6602-28-4
3-Pyridinol N-oxide
3-Hydroxypyridine N-oxide
Pyridin-3-ol 1-oxide
DTXSID70216237
3-Hydroxypyridine-1-oxide
1-Oxopyridin-3-ol
EINECS 229-545-4
NSC 21399
BRN 0107683
5-21-02-00076 (Beilstein Handbook Reference)
DTXCID70138728
229-545-4
inchi=1/c5h5no2/c7-5-2-1-3-6(8)4-5/h1-4,7
3-Hydroxypyridine-N-oxide
3-Hydroxypyridine 1-oxide
1-oxidopyridin-1-ium-3-ol
3-hydroxypyridin-1-ium-1-olate
3-PYRIDINOL, 1-OXIDE
3-pyridinol 1-oxide
3-Pyridinol-1-oxide
MFCD00006200
NSC-21399
hydroxypyridine N-oxide
HQ6MAG8CCL
3-Hydroxypyridine1-oxide
3-hydroxy pyridine N-oxide
3-Hydroxypyridinium-1-olate
SCHEMBL174893
3-Hydroxypyridine N-oxide, 99%
YMEZKRMAPQIBQH-UHFFFAOYSA-N
NSC21399
BBL027566
STL352067
AKOS015906414
SY112163
DB-054858
CS-0199203
H0492
NS00047021
EN300-188549
AC-907/25014065