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8-Hydroxyquinoline N-Oxide

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Identification
Molecular formula
C9H7NO2
CAS number
1123-41-3
IUPAC name
1-oxidoquinolin-1-ium-8-ol
State
State

At room temperature, 8-Hydroxyquinoline N-oxide is typically in a solid state, specifically appearing as a dry, crystalline powder.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
345.70
Boiling point (Kelvin)
618.90
General information
Molecular weight
161.16g/mol
Molar mass
161.1520g/mol
Density
1.5350g/cm3
Appearence

8-Hydroxyquinoline N-oxide typically appears as a white, crystalline powder. It may become light yellow when exposed to air and light for extended periods. The compound is odourless.

Comment on solubility

Solubility of 1-oxidoquinolin-1-ium-8-ol

The compound 1-oxidoquinolin-1-ium-8-ol exhibits interesting solubility characteristics that are worth noting. Its solubility can vary significantly based on several factors:

  • Solvent Polarity: 1-oxidoquinolin-1-ium-8-ol tends to be more soluble in polar solvents due to the presence of the hydroxyl group and the positively charged nitrogen atom in its structure.
  • pH of the Solution: The ionization of the hydroxyl and nitrogen groups can be affected by the pH, impacting its solubility. In acidic conditions, for example, the molecule may exist in a more soluble ionized form.
  • Temperature: As with many organic compounds, increasing the temperature may enhance solubility, allowing more of the compound to dissolve in a given solvent.

Overall, **1-oxidoquinolin-1-ium-8-ol** is influenced by the aforementioned factors, and its solubility can be summarized with the following key points:

  1. **Increased solubility in polar solvents** such as water and alcohols.
  2. **Variable solubility** depending on the pH of the environment.
  3. **Temperature-dependent solubility behavior**, with higher temperatures typically promoting dissolution.

In summary, while 1-oxidoquinolin-1-ium-8-ol offers some intriguing prospects for solubility studies, its behavior can be complex and requires careful consideration of environmental conditions.

Interesting facts

Interesting Facts about 1-oxidoquinolin-1-ium-8-ol

1-oxidoquinolin-1-ium-8-ol is a fascinating compound that stands out in the realm of organic chemistry. Its unique structure and properties make it an intriguing subject for research and application. Here are some noteworthy points:

  • Quinoline Derivative: This compound is a derivative of quinoline, a bicyclic compound that features a fused benzene and pyridine ring. Quinoline derivatives are known for their diverse biological activities.
  • Biological Significance: Compounds like 1-oxidoquinolin-1-ium-8-ol have shown promise in various biological applications, including antimicrobial and anticancer properties, making them valuable in pharmaceutical research.
  • Protonation Behavior: The presence of the oxido group can influence its protonation behavior, which may lead to interesting acid-base characteristics that can be exploited in various chemical environments.
  • Fluorescent Properties: Certain quinoline derivatives are known for their fluorescence, which can be utilized in sensing applications and as indicators in biochemical assays.

In summary, 1-oxidoquinolin-1-ium-8-ol is more than just a chemical compound; it is a gateway to understanding a plethora of biological processes and chemical applications. As scientists continue to explore its properties, there's potential for discovering innovative uses in medicine and materials science.


Synonyms
1127-45-3
8-Hydroxyquinoline-N-oxide
8-Hydroxyquinoline 1-oxide
8-Hydroxyquinoline N-oxide
8-QUINOLINOL, N-OXIDE
NSC-21656
OXYQUINOLINE N-OXIDE
TMI4LD989P
DTXSID70150142
HYDROXYQUINOLINE 1-OXIDE, 8-
CCRIS 4451
EINECS 214-430-3
NSC 21656
UNII-TMI4LD989P
BRN 0128737
5-21-03-00276 (Beilstein Handbook Reference)
DTXCID6072633
214-430-3
fjkuoccqeblpnx-uhfffaoysa-n
8-Quinolinol, 1-oxide
1-oxidoquinolin-1-ium-8-ol
8-HYDROXYQUINOLIN-N-OXIDE
o-Hydroxyquinoline N-oxide
8-Quinolinol N-oxide
Quinolin-8-ol 1-oxide
MFCD00006739
MLS002638801
8-hydroxyquinolin-1-ium-1-olate
NSC21656
quinolin-8-ol-N-oxide
8-Hydroxychinolin-N-oxid
8-Hydroxyquinoline1-oxide
SCHEMBL100824
8-Quinolinol N-oxide, 98%
quinoline 1-oxide, 8-hydroxy-
CHEMBL1650601
CHEBI:192375
HMS3082E11
1-oxo-1lambda(5)-quinolin-8-ol
AKOS015897108
AC-7833
AS-13601
SMR001548266
SY009330
DB-041116
H1272
NS00045289
Q27290026