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Bis(2,3-epoxypropyl)-piperidine

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Identification
Molecular formula
C14H24N2O2
CAS number
5059-36-3
IUPAC name
1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine
State
State

At room temperature, bis(2,3-epoxypropyl)-piperidine is typically in a liquid state. Its consistency can vary, but it generally maintains a low viscosity, allowing it to flow easily.

Melting point (Celsius)
-25.00
Melting point (Kelvin)
248.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
222.36g/mol
Molar mass
222.3120g/mol
Density
1.1500g/cm3
Appearence

This compound is typically a colorless to yellowish liquid. It possesses a characteristic odor, typical of epoxy compounds, which can be irritating or strong to those who are sensitive to such chemicals. Due to the reactive nature of epoxy groups, it should be handled with care to avoid unwanted reactions.

Comment on solubility

Solubility of 1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine

The solubility of 1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine is a complex topic, influenced by its unique molecular structure. Understanding its solubility requires examining several factors:

  • Polarity: The presence of multiple functional groups in this compound may enhance its polarity, potentially increasing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The molecular structure is likely to facilitate hydrogen bonding, which can improve solubility in polar environments.
  • Solvent Interaction: Solubility might significantly differ across various solvents. For example, it may dissolve well in organic solvents like ethanol or dimethyl sulfoxide (DMSO), while having lower solubility in non-polar solvents.

It is essential to consider that factors such as temperature and pH can influence solubility as well. As a general guideline:

  1. Higher temperatures can enhance solubility for many compounds, so testing at various temperatures is beneficial.
  2. pH changes can impact ionization, which may alter solubility, particularly for compounds containing functional groups sensitive to pH.

In conclusion, while the solubility of 1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine may be favorable in certain conditions, it is paramount to conduct empirical solubility tests across a range of solvents to fully elucidate its behavior in various environments.

Interesting facts

Interesting Facts about 1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine

The compound 1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine belongs to a fascinating class of chemical compounds known for their unique structures and potential biological applications. Here are some intriguing aspects of this compound:

  • Diverse Applications: Compounds like this one are often studied for their roles in medicinal chemistry, particularly in the development of novel pharmaceuticals and therapeutics.
  • Epoxide Chemistry: The presence of the oxirane (epoxide) group within its structure highlights its potential for interesting chemical reactivity. Epoxides are known for their ability to participate in various ring-opening reactions, making them valuable intermediates in organic synthesis.
  • Piperidine Framework: The underlying piperidine rings are significant due to their frequent presence in biologically active molecules. This structural motif can influence the biological activity and properties of compounds in medicinal chemistry.
  • Potential for Research: Given its complex structure, this compound may serve as a valuable tool for researchers exploring the mechanisms of drug action or the development of new synthetic methodologies.
  • Interdisciplinary Links: The study of this compound bridges several fields of science, including organic chemistry, pharmacology, and biochemistry, demonstrating the interconnectedness of scientific disciplines.

In summary, 1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine represents a fascinating example of modern chemical compounds that integrate complex structural features with promising applications. Its study may unveil new pathways in drug discovery and provide insights into chemical reactivity.

Synonyms
Epipropidine
Epoxypropidine
5696-17-3
Eponate
Lilly 28002
Epipropidina
Lilly Res. No. 28002
NSC 56308
1,1'-Bis(2,3-epoxypropyl)-4,4'-bipiperidine
N,N'-Di(2,3-epoxypropyl)-4,4'-bipiperidine
NSC-56308
T3RCY5OD7A
1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)piperidin-4-yl]piperidine
NSC56308
1,1'-bis(oxiran-2-ylmethyl)-4,4'-bipiperidine
Epipropidine; Eponate; Lilly 28002; NSC 56308
Epipropidinum
Epipropidine [USAN:INN]
Epipropidinum [INN-Latin]
Epipropidina [INN-Spanish]
EINECS 227-170-0
UNII-T3RCY5OD7A
BRN 0173943
1,1'-Bis(oxiranylmethyl)-4,4'-bipiperidine
1,1'-Di(2,3-epoxypropyl)-4,4'-bipiperidine
4,4'-Bipiperidine, 1,1'-bis(oxiranylmethyl)-
4,4'-BIPIPERIDINE, 1,1'-BIS(2,3-EPOXYPROPYL)-
Epipropidine (USAN/INN)
EPIPROPIDINE [INN]
EPIPROPIDINE [USAN]
SCHEMBL3660
NCIOpen2_002462
4-23-00-00524 (Beilstein Handbook Reference)
CHEMBL462393
DTXSID20863598
SNYUHPPZINRDSG-UHFFFAOYSA-N
1,3-epoxypropyl)-4,4'-bipiperidine
4, 1,1'-bis(2,3-epoxypropyl)-
N,3-epoxypropyl)-4,4'-bipiperidine
AKOS040746805
WLN: T6NTJ A1- BT3OTJ& D- 2
DS-002725
NS00046793
1,1'-Bis(oxiranylmethyl)-4, 4'-bipiperidine
D04027
1, 1'-Di(2,3-epoxypropyl)-4,4'-bipiperidine
4, 4'-Bipiperidine, 1,1'-bis(oxiranylmethyl)-
1,1'-bis[(oxiran-2-yl)methyl]-4,4'-bipiperidine
4, 4'-Bipiperidine, 1,1'-bis(2,3-epoxypropyl)-
1-(oxiran-2-ylmethyl)-4-[1-(oxiran-2-ylmethyl)-4-piperidyl]piperidine