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α-Pyrrolidinopentiophenone hydrochloride

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Identification
Molecular formula
C16H23NO · HCl
CAS number
1823274-68-2
IUPAC name
1-(p-tolyl)-2-pyrrolidin-1-yl-pentan-1-one;hydrochloride
State
State

At room temperature, α-Pyrrolidinopentiophenone hydrochloride is typically a solid. It is often stored in a cool, dry area away from direct sunlight and moisture to maintain its stability.

Melting point (Celsius)
132.50
Melting point (Kelvin)
405.70
Boiling point (Celsius)
378.40
Boiling point (Kelvin)
651.60
General information
Molecular weight
265.80g/mol
Molar mass
265.7960g/mol
Density
0.9503g/cm3
Appearence

α-Pyrrolidinopentiophenone hydrochloride typically appears as an off-white or pale yellow crystalline powder. As a solid, it may form in small crystalline structures or larger aggregated clumps. Its exact appearance can vary depending on the purity and processing methods used after synthesis.

Comment on solubility

Solubility of 1-(p-tolyl)-2-pyrrolidin-1-yl-pentan-1-one hydrochloride

The solubility of 1-(p-tolyl)-2-pyrrolidin-1-yl-pentan-1-one hydrochloride can be influenced by various factors such as temperature, pH, and the presence of other solutes. Generally, hydrochloride salts like this compound are known for their improved solubility in water compared to their free base counterparts. This is primarily due to the ionic nature of the hydrochloride group, which significantly enhances the polar characteristics of the molecule.

Key Points on Solubility:

  • Water Solubility: Typically, the hydrochloride form is soluble in water, making it easier to handle in various applications.
  • Alcohol Solubility: Moderately soluble in alcohols, which can also serve as convenient solvents for certain reactions.
  • Aqueous Solutions: Stability in aqueous solutions can vary, so it's prudent to check for precipitation under different conditions.
  • Temperature Dependence: Solubility often increases with elevated temperatures, thus, proper thermal management can enhance dissolution rates.

In summary, the solubility of 1-(p-tolyl)-2-pyrrolidin-1-yl-pentan-1-one hydrochloride in water and its favorable solubility behavior in alcohols make it a versatile compound in various chemical processes. Researchers and chemists should always consider these solubility characteristics to optimize their applications.

Interesting facts

Interesting Facts about 1-(p-tolyl)-2-pyrrolidin-1-yl-pentan-1-one Hydrochloride

This compound, commonly referred to in research and pharmaceutical circles, is a powerful entity with intriguing applications and characteristics. Here are some key points that make it noteworthy:

  • Chemical Classification: It belongs to a class of compounds known as catalytic agents, which are often employed in various synthetic processes.
  • Structural Features: The presence of the p-tolyl group lends this compound unique properties such as increased lipophilicity, which can enhance its biological activity.
  • Research Applications: Scientists are exploring its potential in the fields of neuroscience and pharmacology, particularly for its effects on neurotransmitter systems.
  • Legal Status: Due to its psychoactive properties, this compound is subjected to regulation in many countries, which raises important discussions about the ethics of research and drug use.
  • Synthesis: The synthesis of this compound involves multiple steps, often requiring extensive knowledge of organic chemistry techniques, such as reduction and functional group transformations.

Quote: "The study of compounds like 1-(p-tolyl)-2-pyrrolidin-1-yl-pentan-1-one hydrochloride opens a window into the complex relationship between chemistry and biological function."

In conclusion, this compound serves as a significant point of interest for chemists and researchers alike. Its unique structural attributes and potential applications make it a compelling subject for further exploration in scientific studies.

Synonyms
PYROVALERONE HYDROCHLORIDE
Centroton
Thymergix
Pyrovalerone HCl
1147-62-2
F 1983
Pyrovalerone hydrochloride [USAN]
Sp 1059
EINECS 214-556-9
4'-Methyl-2-(1-pyrrolidinyl)valerophenone hydrochloride
1-(p-Methylphenyl)-2-pyrrolidyl-1-pentanone hydrochloride
UNII-Z95Z9C2201
Valerophenone, 4'-methyl-2-(1-pyrrolidinyl)-, hydrochloride
Z95Z9C2201
SP-1059
1-Pentanone, 1-(4-methylphenyl)-2-(1-pyrrolidinyl)-, hydrochloride
1-p-Tolyl-1-oxo-2-pyrrolidino-n-pentane hydrochloride
F-1983
Pyrovalerone hydrochloride (USAN)
PYROVALERONE HYDROCHLORIDE [MI]
PYROVALERONE HYDROCHLORIDE [WHO-DD]
1-PENTANONE, 1-(4-METHYLPHENYL)-2-(1-PYRROLIDINYL)-, HYDROCHLORIDE (1:1)
Pyrovalerone.HCl
1-(4-methylphenyl)-2-pyrrolidin-1-ylpentan-1-one;hydrochloride
DEA No. 1485
Pyrovalerone Hydrochloride (1mg/ml in Methanol)
SCHEMBL121638
CHEMBL2104793
DTXSID70921470
MWRACNBZNVAJHE-UHFFFAOYSA-N
NS00081482
D05663
Pyrovalerone.HCl, 1mg/ml in Methanol (as free base)
Q27295179
4'-methyl-2-(1-pyrrolidinyl) valerophenone hydrochloride
1-(4-Methylphenyl)-2-(pyrrolidin-1-yl)pentan-1-one--hydrogen chloride (1/1)