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1-pentylpiperidine

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Identification
Molecular formula
C10H21N
CAS number
34465-74-6
IUPAC name
1-pentylpiperidine
State
State

At room temperature, 1-pentylpiperidine is in a liquid state.

Melting point (Celsius)
-74.00
Melting point (Kelvin)
199.15
Boiling point (Celsius)
203.00
Boiling point (Kelvin)
476.15
General information
Molecular weight
141.29g/mol
Molar mass
141.2520g/mol
Density
0.8415g/cm3
Appearence

1-Pentylpiperidine generally appears as a clear, colorless liquid. It may develop a yellowish tint over time due to impurities or exposure to air.

Comment on solubility

Solubility of 1-pentylpiperidine

1-pentylpiperidine, with the chemical formula C11H23N, exhibits notable solubility properties due to its unique structure. This compound, which contains a medium-length alkyl chain, shows varying solubility tendencies in different solvents. Here are some key points about its solubility:

  • Polar Solvents: 1-pentylpiperidine has moderate solubility in polar solvents such as water, although it is generally less soluble compared to smaller piperidine derivatives.
  • Non-Polar Solvents: This compound is more soluble in non-polar solvents like hexane or toluene, making it favorable for organic synthesis.
  • Temperature Dependency: The solubility can increase significantly with temperature. As a general rule, higher temperatures tend to enhance solubility in most cases.

The solubility behavior of 1-pentylpiperidine can be attributed to the interplay of its hydrophobic alkyl chain and the polar nitrogen atom in the piperidine ring. Due to this dual nature, it often becomes a subject of interest in the exploration of solvent interactions and solubility principles in organic chemistry.

Interesting facts

Interesting Facts about 1-Pentylpiperidine

1-Pentylpiperidine is a fascinating compound that belongs to the piperidine family, which are six-membered saturated nitrogen-containing heterocycles. Here’s why 1-pentylpiperidine deserves attention:

  • Structural Features: This compound features a pentyl group attached to the piperidine ring, enhancing its hydrophobic nature. Such modifications can significantly influence the compound’s interaction with biological systems.
  • Pharmacological Interest: 1-Pentylpiperidine derivatives have been studied for their potential therapeutic applications, particularly in the fields of neuropharmacology. Its structural similarity to various neurotransmitters offers opportunities for drug design.
  • Emerging Research: Researchers are exploring its role in modulating certain receptors in the brain, which could lead to novel treatments for mood disorders and cognitive enhancement.
  • Safety Considerations: Like many organic compounds, the safety profile of 1-pentylpiperidine needs careful evaluation, especially in pharmacological contexts. Understanding both its beneficial effects and potential toxicity is crucial.

Overall, 1-pentylpiperidine exemplifies the intricate relationship between molecular structure and biological function, making it a subject of great interest in medicinal chemistry.

Synonyms
1-Pentylpiperidine
PIPERIDINE, 1-PENTYL-
N-Amylpiperidine
N-Pentylpiperidine
10324-58-0
Pentylpiperidine
BRN 0103867
1-Amyl piperidine
1-pentyl-piperidine
SCHEMBL44723
5-20-02-00031 (Beilstein Handbook Reference)
SCHEMBL293030
SCHEMBL1080135
SCHEMBL1168662
SCHEMBL2091529
SCHEMBL2094342
SCHEMBL6506370
SCHEMBL11774110
SCHEMBL15658696
DTXSID60145709
AKOS006241949
NS00065089