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1-Phenyl-2-(1-piperidyl)ethanol

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Identification
Molecular formula
C13H19NO
CAS number
552-16-9
IUPAC name
1-phenyl-2-(1-piperidyl)ethanol
State
State

This compound is typically a solid at room temperature, existing in a crystalline or powder form.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
338.00
Boiling point (Kelvin)
611.15
General information
Molecular weight
219.30g/mol
Molar mass
219.3190g/mol
Density
1.0400g/cm3
Appearence

1-Phenyl-2-(1-piperidyl)ethanol typically appears as a white to off-white crystalline powder. It may also appear as a solid in a powdery form.

Comment on solubility

Solubility of 1-phenyl-2-(1-piperidyl)ethanol

1-phenyl-2-(1-piperidyl)ethanol, with its unique structure, exhibits intriguing solubility characteristics that can significantly impact its applications. Understanding these characteristics requires consideration of several key factors:

  • Polarity: The compound contains both a phenyl group and a piperidyl group, which contribute to its overall polarity. This polar nature typically enhances solubility in polar solvents.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) group allows for the potential formation of hydrogen bonds with water and other polar solvents, further increasing its solubility.
  • Solvent Compatibility: 1-phenyl-2-(1-piperidyl)ethanol is generally more soluble in organic solvents such as ethanol and acetone compared to nonpolar solvents, due to the presence of polar functional groups.

In practical applications, it is often found that:

  • It is soluble in alcohols and ethers, which broadens its utility in pharmaceutical formulations.
  • It may have limited solubility in nonpolar solvents, making it less effective in those environments.

In summary, the solubility of 1-phenyl-2-(1-piperidyl)ethanol is influenced by its molecular structure, with a tendency to favor solvation in polar media. This property is essential in determining how this compound can be utilized in various chemical and biological processes.

Interesting facts

Interesting Facts about 1-phenyl-2-(1-piperidyl)ethanol

1-phenyl-2-(1-piperidyl)ethanol, commonly referred to as a piperidine derivative, is a compound that highlights the fascinating intersection of organic chemistry and medicinal science.

Key Characteristics

  • Versatile Biological Activity: This compound is known for its potential pharmacological properties, making it a candidate for research in various therapeutic areas, including neurological and psychiatric disorders.
  • Structural Significance: The presence of both a phenyl group and a piperidine ring in its structure provides a unique ability to interact with biological targets, enhancing its effectiveness as a pharmaceutical agent.
  • Research and Development: Studies have shown that piperidine derivatives often exhibit antidepressant, anxiolytic, and even antipsychotic effects, showcasing their potential as mood stabilizers.

Chemistry in Action

The synthesis of 1-phenyl-2-(1-piperidyl)ethanol involves various organic reactions that are fundamental in chemistry practices:

  • Reduction Reactions: This compound can be synthesized from ketones or aldehydes through reduction with appropriate reagents.
  • Catalytic Processes: Catalysts may be employed to enhance selectivity and yield during the synthesis, illustrating a significant aspect of green chemistry.
  • Functional Groups: The alcohol functional group plays a critical role in reactivity, influencing the compound’s ability to form ester linkages or engage in substitution reactions.

Potential Applications

This compound is a prime candidate for further study due to:

  • Drug Development: There is ongoing research exploring its use in developing new medications.
  • Targeted Therapy: Its unique structure allows for the design of analogs that could offer improved efficacy and reduced side effects.

As researchers continue to investigate the intricate properties and uses of 1-phenyl-2-(1-piperidyl)ethanol, it promises to unveil new strategies for drug discovery and development in the ever-evolving field of medicinal chemistry.

Synonyms
1-phenyl-2-piperidin-1-ylethanol
2480-56-0
1-phenyl-2-(piperidin-1-yl)ethan-1-ol
alpha-Phenylpiperidine-1-ethanol
1-Phenyl-2-piperidinoethanol
NSC35704
1-Piperidineethanol, .alpha.-phenyl-
WLN: T6NTJ A1YQR
SCHEMBL1460306
CHEMBL1863743
Piperidinomethyl-1-phenylcarbinol
DTXSID00274587
WMZSIEGEKUAGJB-UHFFFAOYSA-N
1-phenyl-2-piperidin-1-yl-ethanol
NSC-35704
STL220634
1-phenyl-2-(piperidin-1-yl)ethanol
1-(.beta.-Hydroxyphenethyl)piperidine
AKOS008925567
NCGC00184213-01
NCGC00184213-02
Benzyl alcohol, .alpha.-(piperidinomethyl)-
Z31367734