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2-Amphetamine

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Identification
Molecular formula
C18H23NO
CAS number
461-84-7
IUPAC name
1-phenyl-2-(2-phenylpropylamino)propan-1-ol
State
State

At room temperature, 2-Amphetamine is found in solid-state, generally as a powder. It is often handled in controlled laboratory environments due to its psychoactive properties.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
225.34g/mol
Molar mass
225.3360g/mol
Density
1.0480g/cm3
Appearence

2-Amphetamine typically appears as a white, crystalline solid. It is usually in the form of a powder or fine crystals, and it is often prepared in hydrochloride salt form for stability and ease of handling.

Comment on solubility

Solubility of 1-phenyl-2-(2-phenylpropylamino)propan-1-ol

The solubility of 1-phenyl-2-(2-phenylpropylamino)propan-1-ol, a complex organic compound, can be influenced by various factors. Understanding its solubility characteristics is essential for applications in pharmaceuticals and organic chemistry.

Solubility Characteristics

  • Solvent Polarity: This compound may exhibit different solubility in polar vs. non-polar solvents. Typically, compounds with aromatic rings tend to be more soluble in organic solvents due to their hydrophobic nature.
  • Functional Groups: The presence of an alcohol group (-OH) suggests potential hydrogen bonding, which can enhance solubility in polar solvents like water, although the extensive aromatic structures can hinder complete solubility.
  • Temperature Influence: As with many organic compounds, increasing temperature may improve solubility. This makes it important to consider during experimental procedures.

In summary, while 1-phenyl-2-(2-phenylpropylamino)propan-1-ol may show some level of solubility, the extent and nature (polar vs. non-polar) are strongly dependent on the solvent system and environmental conditions. Careful experimental determination of its solubility profile is recommended to fully understand its behavior in various chemical environments.

Interesting facts

Exploring 1-phenyl-2-(2-phenylpropylamino)propan-1-ol

This fascinating compound, known as 1-phenyl-2-(2-phenylpropylamino)propan-1-ol, is part of a family of substances that exhibit intriguing pharmacological properties. Here are some captivating insights into this compound:

  • Pharmaceutical Potential: This compound has garnered attention for its potential use in pharmacology, specifically as a chiral amine which can influence the pharmacodynamics of various therapeutic agents.
  • Stereochemistry: The stereochemical arrangement of the compound plays a crucial role in determining its biological activity. The configuration can impact how the compound interacts with biological targets, making it a subject of keen interest in medicinal chemistry.
  • Structure-Activity Relationship (SAR): The presence of phenyl groups in its structure is notable as they often enhance lipophilicity, potentially aiding in the compound's ability to cross biological membranes, such as the blood-brain barrier. This aspect is vital for compounds designed to engage with the central nervous system.
  • Research Tool: 1-phenyl-2-(2-phenylpropylamino)propan-1-ol serves as a valuable research tool in the study of neurotransmitter systems and could lead to the development of new therapeutic approaches for neuropsychiatric disorders.
  • Designer Drugs: Its structural features suggest potential for misuse as a designer drug, leading to concerns regarding safety and regulation within the scientific community.

In conclusion, 1-phenyl-2-(2-phenylpropylamino)propan-1-ol stands at the intersection of medicinal chemistry and pharmacology, exemplifying the intricate relationship between chemical structure and biological function. As scientists continue to unravel its properties, this compound may illuminate pathways to innovative treatments and a clearer understanding of receptor dynamics in biological systems.