Skip to main content

1-Phenyl-2-(2-pyridylamino)ethanol

ADVERTISEMENT
Identification
Molecular formula
C13H14N2O
CAS number
103-74-2
IUPAC name
1-phenyl-2-(2-pyridylamino)ethanol
State
State

At room temperature, 1-Phenyl-2-(2-pyridylamino)ethanol is typically in a solid state. The compound can sublimate if conditions are conducive or if improperly stored.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
433.60
Boiling point (Kelvin)
706.75
General information
Molecular weight
214.27g/mol
Molar mass
214.2650g/mol
Density
1.1734g/cm3
Appearence

1-Phenyl-2-(2-pyridylamino)ethanol generally appears as a white to off-white crystalline solid. Its appearance may vary slightly due to impurities and particle size.

Comment on solubility

Solubility of 1-phenyl-2-(2-pyridylamino)ethanol

1-phenyl-2-(2-pyridylamino)ethanol exhibits unique solubility characteristics that are influenced by its molecular structure. Understanding the solubility of this compound involves considering several key factors:

  • Polarity: The presence of both a hydroxyl group (-OH) and amino group (-NH2) contributes to its overall polarity, aiding in solubility in polar solvents.
  • Hydrogen Bonding: The ability of the -OH and -NH2 groups to participate in hydrogen bonding significantly enhances its solubility in water.
  • Solvent Interaction: This compound is likely to be more soluble in alcohols and polar organic solvents compared to nonpolar solvents due to similar interactions.
  • pH Dependence: The solubility can change with pH; at higher pH levels, the amino group can deprotonate, potentially increasing solubility in certain conditions.

Generally, it can be stated that 1-phenyl-2-(2-pyridylamino)ethanol may dissolve well in polar environments, but careful optimization of conditions is necessary for applications, especially in biological settings. As stated, “A compound's solubility is a dance of molecular forces and interactions.” Thus, careful consideration of these factors is essential when evaluating its practical applications.

Interesting facts

1-Phenyl-2-(2-pyridylamino)ethanol: An Insightful Exploration

1-phenyl-2-(2-pyridylamino)ethanol is a fascinating compound that straddles the realms of organic chemistry and medicinal applications. This compound is particularly notable for its potential role as a therapeutic agent in various biological contexts. Here are some intriguing aspects:

  • Building Block for Pharmaceuticals: Compounds like 1-phenyl-2-(2-pyridylamino)ethanol serve as essential building blocks in the synthesis of more complex pharmaceutical agents, contributing to advances in drug discovery.
  • Chirality and Isomerism: The presence of both a phenyl and a pyridyl group in its structure introduces chirality, leading to the possibility of different isomers. This characteristic can significantly influence the compound's biological activity.
  • Role in Coordination Chemistry: The nitrogen atoms in the pyridyl group can act as ligands, making this compound interesting in coordination chemistry where it can form complexes with various metal ions.
  • Potential as a Neuroprotective Agent: Preliminary research indicates that similar compounds may exhibit neuroprotective properties, making them candidates for the treatment of neurodegenerative diseases.
  • Research Tool: This compound can also be utilized as a tool in biological research to study receptor interactions and signaling pathways.

Overall, 1-phenyl-2-(2-pyridylamino)ethanol embodies the rich intersection of chemistry and pharmacology, making it a subject of higher interest for scientists and students alike.

Synonyms
Fenyramidol
Phenyramidol
Cabral
Evasprin
Evasprine
Bonapar
553-69-5
Vilexin
Feniramidol
Feniramidolo
Fenyramidolum
Phenylramidol
(+-)-Phenyramidol
Evaspirine
Feniramidolo [DCIT]
Fenyramidol [INN:BAN]
Feniramidol [INN-Spanish]
Fenyramidolum [INN-Latin]
NSC 23634
1-phenyl-2-(pyridin-2-ylamino)ethanol
Benzenemethanol, .alpha.-[(2-pyridinylamino)methyl]-
EINECS 209-044-7
NSC-23634
2-(beta-Hydroxyphenethylamino)pyridine
(+/-)-PHENYRAMIDOL
Fenyramidol (INN)
BRN 0169969
Elan
R3V02WL7O3
alpha-(2-Pyridylaminomethyl)benzyl alcohol
FENYRAMIDOL [INN]
MJ-505
PHENYRAMIDOL [MI]
1-Phenyl-2-(2-pyridinylamino)ethanol
Benzenemethanol, alpha-((2-pyridinylamino)methyl)-
Phenyramidol (Hydrochloride)
FENYRAMIDOL [WHO-DD]
DTXSID00862185
5-22-08-00301 (Beilstein Handbook Reference)
Benzyl alcohol, .alpha.-[(2-pyridylamino)methyl]-
BENZYL ALCOHOL, alpha-((2-PYRIDYLAMINO)METHYL)-
2-(.beta.-Hydroxyphenethylamino)pyridine
NSC17777
Feniramidol (INN-Spanish)
Fenyramidolum (INN-Latin)
.alpha.-[(2-Pyridylamino)methyl]benzyl alcohol
BENZYL ALCOHOL, .ALPHA.-((2-PYRIDYLAMINO)METHYL)-
BENZENEMETHANOL, .ALPHA.-((2-PYRIDINYLAMINO)METHYL)-
1-phenyl-2-((pyridin-2-yl)amino)ethan-1-ol
1-phenyl-2-[(pyridin-2-yl)amino]ethan-1-ol
Benzyl alcohol, alpha-[(2-pyridylamino)methyl]-
UNII-R3V02WL7O3
Cabrale
Phenyramidol-HCl
Elan (Salt/Mix)
Miodar (Salt/Mix)
Analexin (Salt/Mix)
Abbolexin (Salt/Mix)
(.+/-.)-Phenyramidol
WLN: T6NJ BM1YQR
SCHEMBL21963
Fenyramidol (*hydrochloride*)
(.+-.)-PHENYRAMIDOL
CHEMBL1697767
DTXCID80810987
CHEBI:134888
BDBM235694
NSC23634
1-phenyl-2-(2-pyridylamino)ethanol
Fenyramidol (VAN) (*hydrochloride*)
AKOS008926639
DB13414
1-phenyl-2-(pyridin-2-ylamino)-ethanol
1-Phenyl-2-(2-pyridinylamino)ethanol #
NCI60_001490
.alpha.-(2-Pyridylaminomethyl)benzyl alcohol
NS00080453
Pyridine, 2-(.beta.-hydroxyphenethylamino)-
D07953
SR-01000944835
2-(beta-hydroxyphenethylamino)pyridine hydrochloride
ALPHA-(2-PYRIDINYLAMINOMETHYL)BENZENEMETHANOL
Q5443698
SR-01000944835-1
Z31268347
Benzenemethanol, alpha-((2-pyridinylamino)methyl)-(9CI)
{.Alpha.-[(2-Pyridylamino)methyl]benzyl} alcohol hydrochloride
{.Alpha.-[(2-Pyridylamino)methyl]benzyl} alcohol monohydrochloride
Benzyl alcohol, .alpha.-(2-pyridyl-aminomethyl)-, hydrochloride
Benzenemethanol, {.alpha.-[(2-pyridinylamino)methyl]-,} monohydrochloride
Benzyl alcohol, {.alpha.-[(2-pyridylamino)methyl]-,} monohydrochloride
209-044-7