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Desloratadine hydrochloride

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Identification
Molecular formula
C19H20ClN3O
CAS number
100643-71-8
IUPAC name
1-phenyl-2-(2-pyridylamino)ethanol;hydrochloride
State
State

At room temperature, desloratadine hydrochloride is a solid substance, often used in tablet or capsule form in medications.

Melting point (Celsius)
241.00
Melting point (Kelvin)
514.15
Boiling point (Celsius)
-82.20
Boiling point (Kelvin)
190.95
General information
Molecular weight
213.28g/mol
Molar mass
213.2750g/mol
Density
1.2000g/cm3
Appearence

Desloratadine hydrochloride is typically available as a white to off-white crystalline powder. It is often used in its solid state for pharmaceutical formulations.

Comment on solubility

Solubility of 1-Phenyl-2-(2-pyridylamino)ethanol Hydrochloride

The solubility of 1-phenyl-2-(2-pyridylamino)ethanol hydrochloride is an important characteristic that affects its application in various fields. Generally, this compound is known to be soluble in a range of solvents, primarily due to the presence of the hydrochloride moiety. Here are some key points regarding its solubility:

  • Water Solubility: This compound exhibits notable solubility in water, which can be attributed to the ionic nature of the hydrochloride form. It may easily integrate into aqueous solutions, facilitating its utilization in biological and chemical processes.
  • Solvent Compatibility: In addition to water, it is likely to dissolve in polar organic solvents, enhancing its versatility. Common solvents such as ethanol and methanol may offer suitable environments for dissolution.
  • pH Dependency: As with many hydrochloride salts, the solubility can be influenced by the pH of the solution. An acidic environment typically improves solubility, while alkaline conditions may lead to precipitation.

In summary, the solubility properties of 1-phenyl-2-(2-pyridylamino)ethanol hydrochloride make it a compound of interest in various chemical applications, allowing it to be effectively employed in both research and practical scenarios. Understanding its solubility helps in optimizing its use in formulations and reactions.

Interesting facts

Interesting Facts about 1-phenyl-2-(2-pyridylamino)ethanol; hydrochloride

1-phenyl-2-(2-pyridylamino)ethanol; hydrochloride is a fascinating compound that finds its applications in various fields, including medicinal chemistry and pharmaceutical research. Here are some intriguing aspects of this compound:

  • Biological Activity: This compound is known for its potential biological activities, which may include antimicrobial and anti-inflammatory properties. Researchers are exploring its ability to inhibit certain biological processes in pathogens and inflammation pathways.
  • Pyridine Connection: The presence of the pyridine ring enriches the compound's properties. Pyridine derivatives are often associated with important biological activities, making them valuable in drug development.
  • Chiral Center: The compound features a chiral center due to its asymmetric carbon atom. This chirality can lead to different biological effects between its enantiomers, highlighting the importance of stereochemistry in drug design.
  • Complexation: The amino group in this compound can participate in complexation reactions with metal ions. This characteristic can be utilized in developing medicinal agents or imaging agents in biochemical studies.

In summary, 1-phenyl-2-(2-pyridylamino)ethanol; hydrochloride not only serves as a candidate for drug discovery but also represents the intricate relationship between molecular structure and function in biological systems. As research continues to unfold, the compound may lead to new therapeutic breakthroughs or enhance our understanding of chemical interactions in living organisms.

Synonyms
Phenyramidol hydrochloride
326-43-2
Fenyramidol hydrochloride
Abbolexin
Analexin
Betapirin
Firmalgil
Vazalmin
Verbanol
Miodar
Phenyramidol HCl
Cabral hydrochloride
Phenylramidol hydrochloride
Elan
NSC-17777
Fenyramidol hcl
Evasprine hydrochloride
IN 511 hydrochloride
Phenyramidol hydrochloride [USAN]
IN 511
MJ 505
EINECS 206-308-3
UNII-M574V6XQH7
M574V6XQH7
1-phenyl-2-(pyridin-2-ylamino)ethanol hydrochloride
Benzenemethanol, alpha-((2-pyridinylamino)methyl)-, monohydrochloride
IN-511
ALPHA-[(2-PYRIDYLAMINO)METHYL]BENZYL ALCOHOL MONOHYDROCHLORIDE
alpha-((2-Pyridylamino)methyl)-benzyl alcohol hydrochloride
alpha-((2-Pyridylamino)methyl)benzyl alcohol monohydrochloride
Benzyl alcohol, alpha-(2-pyridyl-aminomethyl)-, hydrochloride
Phenyramidol Hydrochloride (USAN)
PHENYRAMIDOL HYDROCHLORIDE [MI]
326-43-2 (HCl)
FENYRAMIDOL HYDROCHLORIDE [MART.]
FENYRAMIDOL HYDROCHLORIDE [WHO-DD]
NSC17777
BENZYL ALCOHOL, alpha-((2-PYRIDYLAMINO)METHYL)-, MONOHYDROCHLORIDE
BENZENEMETHANOL, .ALPHA.-((2-PYRIDINYLAMINO)METHYL)-, MONOHYDROCHLORIDE
FENYRAMIDOL HYDROCHLORIDE (MART.)
.alpha.-[(2-Pyridylamino)methyl]benzyl alcohol monohydrochloride
.ALPHA.-((2-PYRIDYLAMINO)METHYL)BENZYL ALCOHOL MONOHYDROCHLORIDE
SCHEMBL121004
CHEMBL1996759
WLN: T6NJ BM1YQR & GH
AKOS027382007
DB-243033
NS00041837
D00755
1-phenyl-2-(pyridin-2-ylamino)ethanol;hydrochloride
1-phenyl-2-(pyridin-2-ylamino)ethanolhydrochloride
Q27283510
1-phenyl-2-[(pyridin-2-yl)amino]ethan-1-ol hydrochloride
.alpha.-[(2-Pyridylamino)methyl]benzyl alcohol hydrochloride