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1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol

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Identification
Molecular formula
C14H21NO2
CAS number
67248-96-4
IUPAC name
1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol
State
State

At room temperature, 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol is typically found as a liquid. Its state may vary slightly with temperature variations around standard room conditions.

Melting point (Celsius)
40.00
Melting point (Kelvin)
313.10
Boiling point (Celsius)
339.80
Boiling point (Kelvin)
612.90
General information
Molecular weight
247.33g/mol
Molar mass
247.3460g/mol
Density
1.0900g/cm3
Appearence

The compound 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol is typically an oily liquid. It can appear as a colorless to pale yellow liquid, depending on its purity and storage conditions. As a liquid, it is often viscous.

Comment on solubility

Solubility of 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol

1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol, a compound featuring a complex structure, exhibits notable solubility characteristics primarily influenced by its functional groups and molecular structure. Its solubility can be summarized as follows:

  • Polar Nature: The presence of the hydroxyl (-OH) group contributes to the compound's polar character, enhancing its ability to dissolve in polar solvents.
  • Interaction with Water: Due to the ability to form hydrogen bonds, 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol is expected to be moderately soluble in water, although its solubility may be limited due to the aromatic component.
  • Solvent Suitability: The compound likely demonstrates greater solubility in organic solvents such as ethanol and methanol, where the nonpolar phenyl group can be effectively accommodated.
  • Temperature Influence: Like many organic compounds, increased temperature may enhance its solubility due to the increased kinetic energy that facilitates solvation processes.

In conclusion, while 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol showcases potential solubility in both polar and nonpolar solvents, the extent of solubility will ultimately depend on the specific conditions such as solvent choice and temperature. Understanding these factors is crucial for applications involving this compound.

Interesting facts

Interesting Facts About 1-Phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol

1-Phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol is a fascinating compound with unique chemical properties and potential applications. Below are some engaging insights:

  • Structural Complexity: The compound features a pyrrolidine ring, which adds a level of structural complexity not commonly found in simpler organic compounds. This cyclic structure can influence the compound's reactivity and interactions with other molecules.
  • Pharmacological Interest: Compounds with similar structures have garnered attention in medicinal chemistry for their potential as pharmaceuticals, particularly in the fields of psychiatry and neurology. The presence of the ethoxy group can alter the bioavailability and efficacy of drugs, making this compound a subject of study for developing new therapeutic agents.
  • Versatile Reactivity: The hydroxyl group in the compound acts as a functional handle for further chemical modifications. This versatility allows chemists to explore numerous synthetic pathways to create derivatives that could exhibit even more interesting biological properties.
  • Chirality in Chemistry: The compound has chiral centers, making it of interest in stereochemistry. Understanding and manipulating chirality is vital in drug design, as enantiomers can exhibit vastly different biological activities.
  • Impact on Neurotransmission: Compounds similar to 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol have been studied for their effects on neurotransmitter systems. Research suggests that altering specific substituents can modulate interactions at receptor sites, highlighting the connection between chemical structure and biological function.

In conclusion, 1-phenyl-2-(2-pyrrolidin-1-ylethoxy)ethanol embodies a rich tapestry of chemical properties and potential applications, making it a noteworthy compound in both academic research and practical applications in medicinal chemistry.

Synonyms
785-34-2
alpha-((2-(1-Pyrrolidinyl)ethoxy)methyl)benzyl alcohol
BRN 1644817
BENZYL ALCOHOL, alpha-((2-(1-PYRROLIDINYL)ETHOXY)METHYL)-
5-20-01-00208 (Beilstein Handbook Reference)
DTXSID20999801
1-Phenyl-2-(2-(pyrrolidin-1-yl)ethoxy)ethanol
1-Phenyl-2-[2-(pyrrolidin-1-yl)ethoxy]ethan-1-ol