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Chlorpheniramine Maleate

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Identification
Molecular formula
C20H23ClN2O
CAS number
113-92-8
IUPAC name
1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride
State
State

Chlorpheniramine maleate is typically a solid at room temperature.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
388.87g/mol
Molar mass
388.8710g/mol
Density
1.1450g/cm3
Appearence

Chlorpheniramine maleate is a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. It may also appear granular and tends to attract moisture from the environment, known as hygroscopicity.

Comment on solubility

Solubility of 1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride

The compound 1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride showcases notable solubility characteristics owing to its ionic nature and structural composition. Understanding its solubility behavior can provide valuable insights into its applicability and functionality.

Solubility Characteristics

  • Ionic Nature: The presence of the chloride ion enhances the solubility of this compound in polar solvents, particularly water. Ionic compounds generally dissolve well in polar solvents due to ion-dipole interactions.
  • Hydrogen Bonding: The -OH group in the molecule can establish hydrogen bonds, further facilitating solubility in aqueous environments. This is important for biological interactions and pharmacological activity.
  • Solvent Dependence: In non-polar solvents, the solubility is expected to be significantly lower due to the lack of suitable interactions to overcome the lattice energies of the ionic components.
  • pH Sensitivity: The solubility may also vary with pH; in acidic conditions, protonation of the pyridine nitrogen can improve solubility, whereas in basic conditions, deprotonation could lead to decreased solubility.

In conclusion, the solubility of 1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride is influenced by several factors, primarily its ionic character and ability to form hydrogen bonds. Thus, it becomes essential to consider these aspects when evaluating the behavior of this compound in different solvent systems.

Interesting facts

Introduction to 1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride

1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride is an intriguing chemical compound that showcases the fascinating intersection of organic chemistry and medicinal applications. This compound belongs to a class of chemicals known for their biological activity, particularly in pharmaceutical research.

Key Features of the Compound

  • Quaternary Ammonium Character: The presence of the pyridin-1-ium structure suggests that this compound has quaternary ammonium characteristics, which can be vitally important in medicinal chemistry and can influence its pharmacological properties.
  • Diverse Applications: Compounds featuring both aromatic and aliphatic systems often exhibit a diverse range of biological interactions. This versatility can lead to potential applications in drug development, particularly as anti-cancer or anti-inflammatory agents.
  • Amine Functionality: The amine group within the molecule can act as a proton acceptor, making it essential for interactions at biological targets.

Biological Importance

Exploring the biological interactions of this compound could reveal:

  • Potential Target Interactions: Studying how this compound binds to various biological molecules could pave the way for further drug development.
  • Therapeutic Uses: The structural components may allow this compound to participate in complex biochemical pathways, suggesting potential therapeutic roles.

Innovation in Molecular Design

As a compound with multiple functional groups, its study invites chemists to explore various synthesis methods, structural modifications, and the resultant effects on biological activity. This underscores the importance of molecular design in the field of medicinal chemistry.

In the ever-evolving landscape of chemical research, 1-phenyl-2-(pyridin-1-ium-3-ylmethylamino)propan-1-ol;chloride serves as a prime example of how organic structures can lead to exciting discoveries and innovations in drug design and development.

Synonyms
BS-29
alpha-(1-((3-Pyridylmethyl)amino)ethyl)benzyl alcohol hydrochloride
BENZYL ALCOHOL, alpha-(1-((3-PYRIDYLMETHYL)AMINO)ETHYL)-, HYDROCHLORIDE
13695-12-0