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1-phenyl-2-thiohydantoin

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Identification
Molecular formula
C9H8N2OS
CAS number
4041-05-2
IUPAC name
1-phenyl-2-sulfanyl-4H-imidazol-5-one
State
State

At room temperature, 1-phenyl-2-thiohydantoin is generally found in a solid state. It is not volatile, reflecting its relatively high boiling point. Its crystalline structure is typical of many organic compounds with aromatic rings.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.20
Boiling point (Celsius)
308.50
Boiling point (Kelvin)
581.60
General information
Molecular weight
192.24g/mol
Molar mass
192.2410g/mol
Density
1.3400g/cm3
Appearence

The compound, 1-phenyl-2-thiohydantoin, typically appears as a crystalline solid. It may range from off-white to yellow in color, often depending on the purity and specific conditions. Its solid state and coloration are characteristic of many organic compounds that contain both phenyl and thiocarbonyl groups.

Comment on solubility

Solubility of 1-phenyl-2-sulfanyl-4H-imidazol-5-one

The solubility of 1-phenyl-2-sulfanyl-4H-imidazol-5-one can greatly influence its applications and behaviors in various chemical environments. Generally, the solubility of compounds in solvents can be influenced by numerous factors, including:

  • Molecular Structure: The presence of functional groups, molecular weight, and overall polarity.
  • Solvent Properties: Different solvents can dissolve compounds differently based on their polarity and hydrogen bonding capabilities.
  • Temperature: Increased temperature often increases solubility, enabling better dissolution of solid compounds.
  • pH Levels: Changes in pH can affect ionic forms which may be more or less soluble.

In the case of 1-phenyl-2-sulfanyl-4H-imidazol-5-one, it is anticipated that the compound may demonstrate variable solubility in polar and non-polar solvents due to the presence of both non-polar (the phenyl group) and polar (the imidazole component) characteristics.

Furthermore, one might encounter challenges assessing its solubility purely via qualitative observations as solubility could often range from:

  • Highly soluble in organic solvents like DMSO or DMF.
  • Practically insoluble in water, limiting its use in aqueous solutions.

Conclusively, understanding the solubility of 1-phenyl-2-sulfanyl-4H-imidazol-5-one provides valuable insight for its utilization in pharmaceutical and chemical synthesis, ensuring optimal conditions for its performance in various applications.

Interesting facts

Exploring 1-phenyl-2-sulfanyl-4H-imidazol-5-one

1-phenyl-2-sulfanyl-4H-imidazol-5-one is a fascinating compound that has attracted attention in both medicinal chemistry and materials science. Here are some interesting insights about this unique molecule:

  • Biological Significance: The compound is studied for its potential biological activities, particularly its antimicrobial and antifungal properties. Researchers are investigating how modifications to its structure might enhance its efficacy against various pathogens.
  • Pharmaceutical Applications: Its imidazole core is a common scaffold in drug design. Compounds containing imidazole rings are often found in pharmaceutical agents, which makes this compound an interesting candidate for novel drug development.
  • Structural Diversity: The presence of a phenyl group and a sulfanyl (-SH) group introduces significant variability in chemical reactivity. This opens avenues for synthesizing derivatives that can be studied for different chemical properties and biological activities.
  • Research Potential: As a part of ongoing explorations in heterocyclic chemistry, the characteristics of 1-phenyl-2-sulfanyl-4H-imidazol-5-one are being examined to gain insights into how sulfur-containing compounds can impact enzymatic reactions.
  • Easy Synthesis: One of the advantages of working with imidazole derivatives like this compound is that they can often be synthesized through relatively straightforward chemical reactions, making them accessible for laboratory studies.

In summary, 1-phenyl-2-sulfanyl-4H-imidazol-5-one exemplifies the intriguing intersection of organic chemistry and pharmacology, promising potential benefits that could lead to advances in therapeutic solutions. As always, continual research is needed to unlock the full capabilities of such compounds and their derivatives.