Skip to main content

1-phenyl-2,4-dihydro-1H-isoquinolin-3-one

ADVERTISEMENT
Identification
Molecular formula
C15H13NO
CAS number
30431-80-8
IUPAC name
1-phenyl-2,4-dihydro-1H-isoquinolin-3-one
State
State
Solid at room temperature, typically in the form of crystalline powder or crystals.
Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
451.80
Boiling point (Kelvin)
724.95
General information
Molecular weight
221.27g/mol
Molar mass
221.2600g/mol
Density
1.1280g/cm3
Appearence

1-Phenyl-2,4-dihydro-1H-isoquinolin-3-one appears as a solid at room temperature. It typically forms crystalline substances and is generally found in white to off-white colors.

Comment on solubility

Solubility of 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one

The solubility of 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one in various solvents can be quite interesting to explore. This compound, characterized by its unique isoquinoline structure, presents notable features in terms of solubility:

  • Solvent Polarity: The solubility largely depends on the polarity of the solvent used. Generally, non-polar solvents may show better solubility for non-polar compounds.
  • Solvent Type: Common solvents to consider include:
    • Dimethyl sulfoxide (DMSO) - often used for organic compounds
    • Acetone - a moderately polar solvent
    • Water - though usually less soluble due to the organic nature of the compound
  • Temperature Effects: As with most organic compounds, an increase in temperature may enhance solubility, facilitating dissolution.

In summary, the solubility of 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one is influenced by a variety of factors, including the choice of solvent and temperature. It is crucial to conduct solubility tests in order to achieve optimal results based on the intended application.

Interesting facts

Interesting Facts about 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one

1-phenyl-2,4-dihydro-1H-isoquinolin-3-one is a fascinating compound that has garnered attention in the fields of medicinal and organic chemistry. Here are some intriguing insights about this particular compound:

  • Structural Significance: This compound features a unique isoquinoline ring system, which is known for its presence in various natural products and bioactive compounds.
  • Pharmacological Potential: Research has indicated that derivatives of isoquinoline can exhibit a range of biological activities, such as:
    • Antibacterial properties
    • Anticancer effects
    • Anti-inflammatory action
  • Versatile Synthesis: The method of synthesizing 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one can be achieved through various pathways, often involving multi-step reactions that highlight the ingenuity of synthetic organic chemistry.
  • Role in Research: Compounds like this one serve as important intermediates in the development of pharmaceuticals, providing a template for modifying their structure to enhance specific properties.

In the words of one prominent chemist, “The beauty of organic chemistry lies not just in the compounds themselves, but in the interactions and transformations they undergo.” This aptly describes the journey of 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one as it continues to inspire scientific exploration and innovation.

In summary, 1-phenyl-2,4-dihydro-1H-isoquinolin-3-one is an exemplary compound that showcases the endless possibilities of chemical science, bridging the gap between structure and function in the quest for novel therapeutic agents.

Synonyms
1,4-Dihydro-1-phenyl-3(2H)-isoquinolinone
1-phenyl-1,4-dihydroisoquinolin-3(2H)-one
634-000-2
1-Phenyl-1,2-dihydroisoquinolin-3(4H)-one
17507-05-0
1-phenyl-2,4-dihydro-1H-isoquinolin-3-one
MFCD00089450
3(2H)-Isoquinolinone, 1,4-dihydro-1-phenyl-
1-Phenyl-1,2,3,4-tetrahydroisoquinolin-3-one
MLS000107013
SMR000111387
BRN 1532304
3(2H)-Isoquinolinone, 1,4-dihydro-4-phenyl-
5-21-09-00065 (Beilstein Handbook Reference)
ISOQUINOLIN-3-ONE, 1,2,3,4-TETRAHYDRO-1-PHENYL-
Maybridge1_001962
Opera_ID_1067
Cambridge id 5489162
Oprea1_585099
CHEMBL1902410
SCHEMBL11439131
SCHEMBL31350550
HMS547B04
DTXSID20938619
HMS2495N20
CCG-55784
AKOS015999501
1-Phenyl-1,4-dihydroisoquinolin-3-ol
DS-17848
SY115818
DB-337375
1-phenyl-1,4-dihydro-3(2H)-isoquinolinone
CS-0149722
I10861
AB00086899-01
SR-01000609314-2