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Betahistine

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Identification
Molecular formula
C11H13ClN2O
CAS number
5638-76-6
IUPAC name
1-phenyl-3-(pyridin-1-ium-2-ylamino)propan-1-ol;chloride
State
State
Betahistine hydrochloride is typically found in solid form at room temperature, commonly used as a medication for inner ear disorders.
Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
222.30
Boiling point (Kelvin)
495.45
General information
Molecular weight
209.69g/mol
Molar mass
209.6980g/mol
Density
1.7402g/cm3
Appearence
Betahistine hydrochloride is a white crystalline powder. It is freely soluble in water and methanol, soluble in ethanol, and practically insoluble in acetone and in ethyl acetate.
Comment on solubility

Solubility of 1-phenyl-3-(pyridin-1-ium-2-ylamino)propan-1-ol;chloride

The solubility of the compound 1-phenyl-3-(pyridin-1-ium-2-ylamino)propan-1-ol;chloride is influenced by its ionic nature and the presence of polar functional groups. In general, salts like chloride salts tend to exhibit good solubility in polar solvents, particularly water. Here are some key aspects of its solubility:

  • Polar Solvents: The compound is likely to be soluble in polar solvents such as water due to hydrogen bonding and ionic interactions.
  • Non-Polar Solvents: Conversely, it may exhibit limited solubility in non-polar solvents due to the lack of compatibility in terms of intermolecular interactions.
  • Temperature Dependence: The solubility may increase with temperature, which is a common characteristic for many ionic compounds.
  • pH Influence: The presence of the pyridinium group may affect solubility under various pH conditions, potentially enhancing solubility in acidic environments.

In conclusion, factors such as solvent polarity, temperature, and pH play significant roles in determining the solubility of 1-phenyl-3-(pyridin-1-ium-2-ylamino)propan-1-ol;chloride. Understanding these properties is crucial for applications in chemical formulations and biological systems.

Interesting facts

Interesting Facts about 1-phenyl-3-(pyridin-1-ium-2-ylamino)propan-1-ol; chloride

This compound is an intriguing example of a quaternary ammonium salt that showcases the fascinating interplay of organic chemistry and medicinal applications. Here are some noteworthy facts:

  • Dual Functionality: The presence of both a phenyl group and a pyridinium moiety allows this compound to possess unique properties, making it a potential candidate for various biological activities.
  • Biological Relevance: Compounds that contain pyridinium structures are frequently studied for their antimicrobial and antiviral qualities. This adds to the compound's importance in pharmaceutical research.
  • Structural Diversity: The structural framework of this compound allows for modifications, which can lead to derivatives with enhanced activity, better solubility, or improved pharmacokinetic properties.
  • Stability: Quaternary ammonium salts are generally stable under various conditions, making them suitable for applications in drug formulation and design.
  • Potential for New Discoveries: Researchers are continuously exploring new derivatives of compounds like this for their medicinal properties, aiming to combat emerging strains of pathogens.

The exploration of such compounds is crucial as it often leads to innovations in drug discovery and improved therapeutic strategies. As scientists work to unravel the complexities of medicinal chemistry, compounds like 1-phenyl-3-(pyridin-1-ium-2-ylamino)propan-1-ol; chloride will undoubtedly play a significant role.

Synonyms
alpha-(2-(2-Pyridylamino)ethyl)benzyl alcohol hydrochloride
Benzenemethanol, alpha-(2-(2-pyridinylamino)ethyl)-, monohydrochloride
BENZYL ALCOHOL, alpha-(2-(2-PYRIDYLAMINO)ETHYL)-, HYDROCHLORIDE
1922-19-6