Skip to main content

HPY-1

ADVERTISEMENT
Identification
Molecular formula
C32H27N3O
CAS number
164530-97-4
IUPAC name
1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one
State
State

At room temperature, HPY-1 is usually found in a solid state.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.00
Boiling point (Celsius)
289.00
Boiling point (Kelvin)
562.00
General information
Molecular weight
433.51g/mol
Molar mass
433.5060g/mol
Density
1.3440g/cm3
Appearence

HPY-1 is typically a crystalline solid that may appear as a powder.

Comment on solubility

Solubility of 1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one

The solubility of the compound 1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one (C32H27N3O) is influenced by several factors:

  • Polarity: The presence of nitrogen (N) atoms in the structure suggests that the compound may exhibit some degree of polarity, which could affect its solubility in various solvents.
  • Solvent Compatibility: Typically, such compounds may be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) or methanol, while showing limited solubility in polar solvents like water due to hydrophobic character.
  • Functional Groups: The pyridyl groups may enhance solubility in certain environments, providing coordination sites, and potentially interacting with solvent molecules.

In summary, the solubility of 1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one can be described as

  • Moderate in organic solvents
  • Limited in polar solvents, particularly water

Understanding the solubility of this compound is crucial for its application in fields such as pharmaceuticals, where solvent interactions can play a significant role in bioavailability and efficacy.

Interesting facts

Interesting Facts about 1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one

1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one is an intriguing compound in the field of organic chemistry due to its complex structure and potential applications. Here are some key points that highlight its significance:

  • Multi-functionalism: This compound exhibits a unique combination of features that can make it a candidate for various applications, particularly in medicinal chemistry and materials science. Its indolin-2-one moiety is known for its biological activity.
  • Bioactivity: Compounds that contain an indolinone scaffold have been extensively studied for their pharmacological properties, displaying anti-inflammatory, antimicrobial, and even anticancer activities.
  • Pyridylmethyl Groups: The presence of two 4-pyridylmethyl substituents contributes to its ability to interact with biological targets, potentially enhancing its solubility and bioavailability.
  • Versatile Synthesis: The molecule can be synthesized through various methods, allowing chemists to experiment with different conditions and reagents to achieve desired substitutions or functional groups.
  • Research Activity: Ongoing research into this compound may uncover new pathways for drug development or the creation of innovative materials with specific properties.

Given its structural complexity and the diverse potential applications, 1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one stands as an excellent example of how synthetic organic compounds can bridge the gap between chemistry and real-world applications, illustrating the profound impact of chemistry on science and technology.

Synonyms
Linopirdine
105431-72-9
Dup 996
1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one
DuP-996
1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one
1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indolin-2-one
1-Phenyl-3,3-bis(4-pyridinylmethyl)-2-indolinone
2H-Indol-2-one, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-
I5TB3NZ94T
NCGC00015590-03
DTXSID6045163
CHEBI:34823
DTXCID4025163
Linopirine
Linopirdine [USAN:INN]
AVIVA
CAS-105431-72-9
UNII-I5TB3NZ94T
Linopirdina
SR-01000075324
MFCD00867216
Tocris-1999
Lopac-L-134
Linopirdine(DuP-996)
LINOPIRDINE [INN]
Linopirdine (USAN/INN)
LINOPIRDINE [USAN]
LINOPIRDINE [MART.]
1-phenyl-3,3-bis(4-pyridylmethyl)indolin-2-one
3,3-bis(4-pyridylmethyl)-1-phenylindolin-2-one
Lopac0_000732
LINOPIRDINE [WHO-DD]
MLS000862189
SCHEMBL122699
CHEMBL319111
GTPL2599
Linopirdine, >=98% (HPLC)
YEJCDKJIEMIWRQ-UHFFFAOYSA-N
HMS2233C05
HMS3262C06
HMS3370B17
Tox21_110177
Tox21_500732
AKOS032946532
Tox21_110177_1
CCG-204817
DB13806
HY-W020468
LP00732
SDCCGSBI-0050710.P002
NCGC00015590-01
NCGC00015590-02
NCGC00015590-04
NCGC00015590-05
NCGC00015590-06
NCGC00015590-07
NCGC00015590-10
NCGC00025338-01
NCGC00025338-02
NCGC00025338-03
NCGC00261417-01
AS-16868
DA-64984
SMR000326952
CS-0039654
EU-0100732
NS00126871
D04741
W12323
3,3-Bis (4-pyridylmethyl)-1-phenylindolin-2-one
3,3-bis(4-pyridinylmethyl)-1-phenylindolin-2-one
Q6554730
SR-01000075324-1
BRD-K59332007-300-01-9
BRD-K59332007-300-02-7
2H-Indol-2-one,1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-
FCC