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Lidoflazine

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Identification
Molecular formula
C22H28ClNO
CAS number
3112-50-9
IUPAC name
1-phenyl-4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-ium-1-yl)butan-1-one;chloride
State
State
At room temperature, Lidoflazine is typically found in a solid state, specifically as a crystalline powder.
Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
488.04g/mol
Molar mass
488.0370g/mol
Density
1.0610g/cm3
Appearence

Lidoflazine appears as a white to off-white crystalline powder. It is often observed to be odorless and has a fine, uniform consistency.

Comment on solubility

Solubility of 1-phenyl-4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-ium-1-yl)butan-1-one;chloride

The solubility of the compound 1-phenyl-4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-ium-1-yl)butan-1-one;chloride can be complex due to its structural characteristics. Generally, we can expect the following:

  • Organic Solvents: This compound is likely to display good solubility in polar organic solvents due to the presence of both aromatic groups and a quaternized nitrogen, which can interact favorably with solvent molecules.
  • Aqueous Solutions: The solubility in water might be limited, akin to many organics with high molecular weight and hydrophobic components. However, the ionic nature from the chloride can enhance its ability to dissolve to some extent.
  • Temperature Effects: Increased temperature generally promotes solubility, so heating may improve the dissolution process significantly.

It's essential to consider that the actual solubility can be influenced by several factors including:

  1. pH of the Solution: Variations in pH may affect the ionization state of the compound, potentially enhancing solubility.
  2. Presence of Co-solvents: Mixing with other solvents can lead to synergetic effects, improving solubility.
  3. Particle Size: Finer powders usually show higher solubility rates compared to their bulk counterparts.

In summary, while the solubility of 1-phenyl-4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-ium-1-yl)butan-1-one;chloride is multifaceted, it is primarily driven by its molecular structure and interactions with specific solvents. As with many chemical compounds, empirical testing often provides the most reliable data regarding solubility.

Interesting facts

Interesting Facts about 1-phenyl-4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-ium-1-yl)butan-1-one; chloride

This intriguing compound is an example of quaternary ammonium compounds that exhibit unique chemical properties and biological activities. Some key points of interest include:

  • Structural Complexity: The compound possesses a multi-ring structure, featuring both a butanone segment and a tetrahydropyridine moiety, which contributes to its diverse reactivity and potential applications.
  • Biological Relevance: Due to its nitrogen-containing structure, this compound has garnered attention for its potential role in medicinal chemistry. Many derivatives of similar structures are explored for their pharmacological effects.
  • Quaternary Ammonium Ion: The presence of the quaternary ammonium group signifies strong ionic interactions, which can influence the compound's solubility and reactivity.
  • Potential Applications: Compounds of this nature are being investigated for various applications, including their use as antimicrobial agents, antidepressants, and other therapeutic agents.
  • Research Opportunities: The structural features present significant opportunities for further research, particularly in modifying the compound's structure to explore its pharmacological potential.

In summary, 1-phenyl-4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-ium-1-yl)butan-1-one; chloride is a fascinating compound that bridges the fields of organic chemistry and medicine. Its complex architecture and biological significance make it a worthy subject for both scientific exploration and application.

Synonyms
4-(4-Phenyl-3,4-dehydro-1-piperidyl)butyrophenone hydrochloride
Trabuton hydrochloride
14777-22-1
Phenoperidone hydrochloride
BUTYROPHENONE, 4-(4-PHENYL-3,4-DEHYDRO-1-PIPERIDYL)-, HYDROCHLORIDE