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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate
State
State
Phenylbutazone is a solid at room temperature. It remains stable in its solid form within standard temperature conditions unless acted upon by external factors that could cause chemical changes.
Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
308.36g/mol
Molar mass
308.3610g/mol
Density
1.2134g/cm3
Appearence

Phenylbutazone is typically found as a white or off-white crystalline powder. It is odorless and tasteless. Its crystalline nature is often described as fine and consistent with many pharmaceutical powders.

Comment on solubility

Solubility of 1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate

The solubility of 1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate is an important consideration for its applications in various chemical contexts. Generally, the solubility of this compound can be influenced by several factors, such as polarity, molecular interactions, and the presence of functional groups. Here are some key points to consider:

  • Polarity: As a compound containing both organic and phosphorus moieties, its solubility may vary between polar and nonpolar solvents.
  • Functional Groups: The presence of dimethoxy groups could enhance solubility in polar solvents due to their ability to form hydrogen bonds.
  • Temperature Effects: Increased temperature typically improves solubility for many compounds, an aspect worth investigating for this specific compound.
  • pH Sensitivity: The behavior of the phosphate group can change under different pH conditions, potentially affecting its solubility.

In summary, the solubility of 1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate is a complex interplay of various factors. Understanding these can lead to more effective utilization of this compound in different chemical processes. As always, empirical testing under controlled conditions is recommended for precise solubility data.

Interesting facts

Interesting Facts About 1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate

1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate is a fascinating compound in the world of organic chemistry, primarily due to its complex structure and potential applications. Here are some notable points about this compound:

  • Structural Features: The compound is a derivative of butenoic acid, specifically designed to include a phosphonate group, which enhances its reactivity and biological interactions.
  • Potential Pharmacological Applications: Research indicates that compounds with phosphonate groups can exhibit a wide range of biological activities. This compound may have implications in medicinal chemistry, potentially serving as a lead compound for drug development.
  • Synthetic Versatility: The incorporation of a phenyl group allows for various substitution reactions, paving the way for the synthesis of more complex molecules through additional functionalization. This characteristic makes it a valuable intermediate in synthetic organic chemistry.
  • Chiral Center: The presence of the 1-phenylethyl group introduces chirality, allowing for the exploration of enantiomeric forms that may exhibit different biological activities. As the quote by J. Willard Gibbs suggests, "There is no such thing as an accident; it is fate misnamed." This emphasizes the serendipitous nature of discovering biologically active compounds.

This compound demonstrates the beauty and complexity of chemical architecture, showcasing how small changes in molecular structure can lead to significant implications in reactivity and function. As research continues, 1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate may reveal even more exciting characteristics and potential applications in various fields.

Synonyms
1-phenylethyl 3-dimethoxyphosphoryloxybut-2-enoate
2-Butenoic acid, 3-((dimethoxyphosphinyl)oxy)-, 1-phenylethyl ester (9CI)
DTXSID20860022
DB-056168
O,O-Dimethyl O-[1-methyl-2-(1-phenylcarbethoxy)vinyl]phosphate