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1-Phenyl-2,4-hexadiyn-1-one

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Identification
Molecular formula
C12H8O
CAS number
60256-22-0
IUPAC name
1-phenylhexa-2,4-diyn-1-one
State
State

1-Phenyl-2,4-hexadiyn-1-one is typically found as a solid at room temperature.

Melting point (Celsius)
32.00
Melting point (Kelvin)
305.15
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.15
General information
Molecular weight
168.19g/mol
Molar mass
168.2010g/mol
Density
1.0460g/cm3
Appearence

1-Phenyl-2,4-hexadiyn-1-one appears as a yellow to pale orange solid. It is typically crystalline in nature, and due to its aromatic phenyl group, it may exhibit a distinct aromatic odor.

Comment on solubility

Solubility of 1-phenylhexa-2,4-diyn-1-one

1-phenylhexa-2,4-diyn-1-one is a compound characterized by its unique structure featuring a phenyl group and multiple alkynyl functional groups. When it comes to solubility, several factors come into play:

  • Solvent Dependence: The solubility of organic compounds like 1-phenylhexa-2,4-diyn-1-one is highly dependent on the nature of the solvent. Generally, it tends to be soluble in non-polar organic solvents such as toluene and chloroform, while it is insoluble in polar solvents like water.
  • Polarity and Hydrogen Bonding: The presence of the carbonyl functional group lends some polarity to the compound; however, the overall structure remains predominately hydrophobic due to the extended hydrocarbon chains. This indicates limited interaction with water molecules.
  • Temperature Effects: Increased temperature can sometimes enhance the solubility of this compound in organic solvents, making it easier to dissolve by providing sufficient kinetic energy to overcome intermolecular forces.

In summary:

  • The main takeaway is that 1-phenylhexa-2,4-diyn-1-one is essentially soluble in non-polar solvents and insoluble in polar solvents.
  • This behavior is a reflection of both its structural characteristics and the fundamental principles of solubility, where "like dissolves like."
Interesting facts

Interesting Facts about 1-Phenylhexa-2,4-diyn-1-one

1-Phenylhexa-2,4-diyn-1-one is a fascinating compound in the world of organic chemistry, primarily due to its unique structure and potential applications. Below are some intriguing aspects of this compound:

  • Conjugated System: The compound features a conjugated system of double bonds which contributes to its interesting chemical reactivity and potential use in various synthetic processes.
  • Biological Activity: There is ongoing research into the biological activities of diynones like 1-phenylhexa-2,4-diyn-1-one, particularly their roles as potential anti-cancer agents.
  • Synthesis: This compound can be synthesized through various methods, including the utilization of alkynyl metal reagents, making it an attractive target for synthetic organic chemists.
  • Applications: Beyond its potential biological uses, 1-phenylhexa-2,4-diyn-1-one may also find applications in materials science, particularly in the development of advanced polymers and organic materials.
  • Study of Reactivity: The presence of the phenyl group provides an opportunity to study the effects of substituents on the reactivity of diynones, which can lead to a deeper understanding of organic reaction mechanisms.

As a chemistry student or a researcher, the study of 1-phenylhexa-2,4-diyn-1-one showcases the importance of novel compounds in innovative applications across chemical and pharmaceutical industries. The exploration of such compounds can lead to groundbreaking discoveries that shape the future of material science and medicinal chemistry.

Synonyms
Capillin
1-phenylhexa-2,4-diyn-1-one
495-74-9
2,4-HEXADIYNOPHENONE
2,4-Hexadiyn-1-one, 1-phenyl-
1-Phenyl-2,4-hexadiyn-1-one
9JXZ3SJG0I
NSC 113499
BRN 1865168
UNII-9JXZ3SJG0I
NSC-113499
CHEBI:3369
DTXSID90197812
DTXCID50120303
2,4-Hexadiyn-1-one, 1-phenyl-(9CI)
1-phenylethanone (acetophenone)
1-phenylethanone, 9ci
4-07-00-01354 (beilstein handbook reference)
acetyl-benzene
fema 2009
methyl phenyl-ketone
nchem.180-comp5
razokruzeqerlh-uhfffaoysa-n
2, 4-Hexadiynophenone
1-Benzoyl-1,3-pentadiyne
2,4-Hexadiynophenone, 8CI
CHEMBL4540891
1-Phenyl-2,4-hexadiyn-1-one #
NSC113499
AKOS006277108
2,4-Hexadiyn-1-one, 1-phenyl- (9CI)
C08398
Q18012475