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Indophenin

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Identification
Molecular formula
C13H9NO2
CAS number
132-31-0
IUPAC name
1-phenylindoline-2,3-dione
State
State

At room temperature, Indophenin is a solid.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
248.00
Boiling point (Kelvin)
521.15
General information
Molecular weight
223.21g/mol
Molar mass
223.2130g/mol
Density
1.3869g/cm3
Appearence

Indophenin typically appears as a bright yellow crystalline solid.

Comment on solubility

Solubility of 1-phenylindoline-2,3-dione

1-phenylindoline-2,3-dione (C13H9N1O2) exhibits some intriguing characteristics regarding its solubility:

  • Solvent Dependence: This compound is generally insoluble in water due to its hydrophobic nature.
  • Organic Solubility: It shows a better solubility profile in various organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO).
  • Temperature Influence: As with many organic compounds, solubility can improve with increased temperature, allowing for more effective dissolution.
  • pH Sensitivity: The solubility of 1-phenylindoline-2,3-dione may vary with changes in pH, which can affect its ionization state and thus its overall solubility.

In summary, while 1-phenylindoline-2,3-dione has limited solubility in aqueous media, it finds greater compatibility in organic solvents and can demonstrate variable solubility influenced by various factors. Understanding these nuances is essential for practical applications and chemical interactions.

Interesting facts

Interesting Facts about 1-phenylindoline-2,3-dione

1-phenylindoline-2,3-dione is a fascinating compound that belongs to the class of indoline derivatives, notable for its distinctive indole-like structure. Its unique characteristics contribute to various applications in the fields of organic chemistry and materials science.

Chemistry and Synthesis

  • Building Block: The compound serves as a pivotal building block for synthesizing more complex organic molecules due to its reactive indoline core.
  • Synthetic Routes: It can be synthesized using several methods, including oxidation of the corresponding indoline or other innovative approaches such as cyclization reactions.

Applications

  • Dyes and Pigments: 1-phenylindoline-2,3-dione is often utilized as a dye precursor due to its vibrant color and stability.
  • Biological Activity: Research has indicated that derivatives of this compound may exhibit significant biological properties, potentially leading to new pharmaceuticals.

Research Perspectives

According to recent studies, compounds related to 1-phenylindoline-2,3-dione have shown promise in:

  • Antioxidant activity
  • Anti-inflammatory effects
  • Antimicrobial properties

The emergence of new synthetic methodologies continues to inspire fresh research avenues for this compound, thus expanding its application range. Scientists are excited about its potential to contribute to innovations in drug design and organic materials.

In summary, 1-phenylindoline-2,3-dione exemplifies the intricate link between structure and function, making it an intriguing subject for study in the ongoing quest for new compounds with valuable applications.

Synonyms
1-Phenylisatin
723-89-7
1-phenylindole-2,3-dione
624-596-2
1-Phenylindoline-2,3-dione
1-Phenyl-1H-indole-2,3-dione
1H-Indole-2,3-dione, 1-phenyl-
N-Phenylisatin
1-phenyl-2,3-dihydro-1H-indole-2,3-dione
1-Phenyl-indole-2,3-dione
Phenyl Isatin
N-phenyl isatin
INDOLE-2,3-DIONE, 1-PHENYL-
SMR000131753
NSC 100013
BRN 0164531
phenylisatin
1-phenyl isatin
MFCD00082681
NSC100013
1-Phenylisatin, 97%
1H-Indole-2,3-dione, 1-phenyl- (9CI)
Isatin-based compound, 13
1-Phenyl-2,3-indolinedione
5-21-10-00247 (Beilstein Handbook Reference)
MLS000521345
MLS002473342
SCHEMBL916808
CHEMBL117447
BDBM22793
DTXSID20222626
HMS2466D08
1-Phenyl-1H-indole-2,3-dione #
AKOS001582739
6L-325S
CCG-202928
NSC-100013
SB64106
NCGC00245965-01
1-Phenyl-2,3-indolinedione, NSC 100013
CS-0071223
EU-0033322
P2279
D92197
A837514
AE-641/30401023
SR-01000597222
SR-01000597222-1
F0850-6840
1‐phenylindole‐2,3‐dione (Compound 6)