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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
1-phenylpyrazolidin-3-one
State
State
Solid at room temperature.
Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
308.37g/mol
Molar mass
308.3660g/mol
Density
1.2000g/cm3
Appearence

Phenylbutazone appears as a white or off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 1-Phenylpyrazolidin-3-one

1-Phenylpyrazolidin-3-one exhibits interesting solubility characteristics which can vary significantly depending on numerous factors. Here are some key points to consider:

  • Polar and Non-Polar Solvents: This compound tends to be more soluble in polar solvents such as water and ethanol due to the presence of functional groups that can engage in hydrogen bonding.
  • Temperature Dependence: Solubility may be enhanced at elevated temperatures, as the increased molecular motion can help to dissolve more of the compound.
  • pH Influence: The solubility of 1-phenylpyrazolidin-3-one can also be affected by the pH of the solution, as ionization may occur, thus affecting the overall solubility in aqueous environments.

Overall, while 1-phenylpyrazolidin-3-one has certain affinities for polar solvents, it is essential to consider various factors such as temperature, solvent type, and pH when assessing its solubility. As a rule of thumb, “like dissolves like”, which means that understanding the molecular interactions will provide deeper insights into its solubility behavior.

Interesting facts

Exploring 1-Phenylpyrazolidin-3-one

1-Phenylpyrazolidin-3-one is an intriguing compound that belongs to the class of pyrazolidinones. This chemical has garnered attention in various fields of research due to its interesting properties and potential applications.

Key Features

  • Pharmacological Significance: 1-Phenylpyrazolidin-3-one has been studied for its anti-inflammatory and analgesic properties, making it a compound of interest in medicinal chemistry.
  • Synthetic Intermediates: It serves as a valuable intermediate in organic synthesis, aiding in the development of more complex compounds.
  • Structural Versatility: The unique pyrazolidinone framework allows for various modifications, leading to a diverse range of derivatives with altered biological activities.
  • Research Insights: Studies have shown that substituents on the phenyl ring can significantly influence the compound's efficacy and selective action on biological targets.

One interesting aspect is the role of the pyrazolidinone moiety in molecular recognition processes, which can enhance the compound’s capability to interact with specific receptors or enzymes. Researchers have stated that, “Understanding the interactions between these compounds and biological targets can pave the way for novel therapeutic agents.”

As interest in pyrazolidinone derivatives continues to evolve, 1-phenylpyrazolidin-3-one stands as a representative example of how simple structural variations can lead to profound implications in drug discovery and development. The ongoing studies and findings may very well uncover new applications and deepen our understanding of its pharmacological potential.

Synonyms
Phenidone
92-43-3
1-PHENYL-3-PYRAZOLIDINONE
1-phenylpyrazolidin-3-one
1-Phenyl-3-pyrazolidone
Fenidon
3-Pyrazolidinone, 1-phenyl-
Pyrazolidinone, 1-phenyl-
1-Phenyl-3-oxopyrazolidine
2-Pyrazolin-3-ol, 1-phenyl-
1-P-3-P
CCRIS 3624
1-Phenylpyrazolid-3-one
EINECS 202-155-1
1-Phenyl-pyrazolidin-3-one
MFCD00003094
NSC 30306
UNII-H0U5612P6K
DTXSID1049433
NSC-30306
CHEMBL7660
1-phenyl-4,5-dihydro-1H-pyrazol-3-ol
MLS002639322
DTXCID0029393
H0U5612P6K
1-PHENYL-3-PYRAZOLIDINONE [MI]
Phenidone A (1-Phenyl-3-pyrazolidinone)
WLN: T5NMVTJ AR
N-phenylpyrazolidin-3-one
ChemDiv3_006595
TimTec1_001225
Oprea1_428400
SCHEMBL235192
SCHEMBL9670254
SCHEMBL10371905
2-Pyrazolin-3-one, 1-phenyl-
1-Phenyl-3-pyrazolidinone, 97%
HMS1491L17
HMS1537H15
HMS3091P11
HMS3886E10
ALBB-010492
NSC30306
Tox21_202877
BDBM50009004
s5520
STK084358
STK741678
AKOS000119161
AKOS003264132
pyrazole, tetrahydro-3-oxo-1-phenyl-
(phenidone)1-Phenyl-pyrazolidin-3-one
1-Phenyl-pyrazolidin-3-one(Phenidone)
2-Pyrazolin-3-ol, 1-phenyl-(7CI)
CCG-207926
CS-W010860
FS-4504
HY-W010144
SDCCGMLS-0064787.P001
CAS-92-43-3
IDI1_024505
1-Phenyl-pyrazolidin-3-one (Phenidone)
NCGC00174656-01
NCGC00260423-01
SMR001548767
SY048400
DB-057302
NS00019857
P0153
EN300-19052
D78316
SR-01000516084
Q3297749
SR-01000516084-1
F0905-7615
Z104472448
14776-33-1