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Clotrimazole

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Identification
Molecular formula
C22H17Cl3O
CAS number
23593-75-1
IUPAC name
1-propoxy-4-[2,2,2-trichloro-1-(4-propoxyphenyl)ethyl]benzene
State
State

The compound is in a solid state at room temperature.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.20
Boiling point (Celsius)
458.60
Boiling point (Kelvin)
731.80
General information
Molecular weight
344.85g/mol
Molar mass
344.8450g/mol
Density
1.2279g/cm3
Appearence

Clotrimazole appears as a white crystalline powder. It is virtually odorless and has a slightly bitter taste. The compound is known for its antifungal properties and is used in pharmaceutical formulations.

Comment on solubility

Solubility of 1-propoxy-4-[2,2,2-trichloro-1-(4-propoxyphenyl)ethyl]benzene

The solubility of 1-propoxy-4-[2,2,2-trichloro-1-(4-propoxyphenyl)ethyl]benzene in various solvents is notably influenced by its complex molecular structure. Understanding its solubility properties can provide valuable insights into its potential applications and behavior in different conditions.

Key Factors Affecting Solubility:

  • Polarity: The compound contains multiple functional groups, affecting its polarity and, consequently, its solubility in polar vs. nonpolar solvents.
  • Hydrophobic Interactions: The presence of chlorine atoms and the organic moieties suggests that it may be more soluble in nonpolar solvents, where hydrophobic effects come into play.
  • Temperature: Increased temperature may enhance solubility in certain cases, as thermal energy disrupts solute-solvent interactions.
  • pH Level: Given the potential for ionization in specific conditions, the pH can influence solubility, especially in aqueous environments.

Due to its unique properties, this compound may exhibit limited solubility in water but better solubility in organic solvents such as ethanol or dichloromethane. It is critical to conduct solubility tests under controlled conditions to ascertain its behavior in real-world applications.


"To understand a compound fully, one must comprehend its solubility." – Unknown

Interesting facts

Interesting Facts About 1-Propoxy-4-[2,2,2-Trichloro-1-(4-propoxyphenyl)ethyl]benzene

1-Propoxy-4-[2,2,2-trichloro-1-(4-propoxyphenyl)ethyl]benzene, often simply referred to by its structural components, is a fascinating compound with several significant attributes and applications in the field of chemistry. Here are some intriguing points to consider:

  • Complex Structure: This compound features a multi-layered structure combining a propoxy group, a trichloroethyl moiety, and a phenyl ring, showcasing the intricate nature of organic synthesis.
  • Pesticide Precursor: Due to its chlorinated nature, it is investigated as a potential metabolite in the study of pesticides, particularly those used in agriculture.
  • Article of Research: Research into compounds like this helps chemists understand the interactions of chlorinated organic compounds in biological systems, making it pivotal in environmental chemistry.
  • Applications in Material Science: Compounds with similar structures have been explored for their abilities to modify thermal and electrical properties in advanced materials.
  • Relevance to Pharmaceuticals: The functional groups present could lead to further investigations in drug design, especially in the context of targeting specific biological pathways.

As a scientist or student delving into organic chemistry, it’s essential to appreciate the depth of study involved in compounds like 1-propoxy-4-[2,2,2-trichloro-1-(4-propoxyphenyl)ethyl]benzene. Each synthesized chemical tells a story of innovation and research potential, providing valuable insights into both environmental and pharmaceutical applications.

In the words of famous chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." The exploration of compounds like this encourages a plethora of ideas and research opportunities in the field of chemistry. Keep pushing forward in your journey of discovery!

Synonyms
1,1,1-Trichloro-2,2-bis(p-propoxyphenyl)ethane
2,2-Bis(p-propoxyphenyl)-1,1,1-trichloroethane
BRN 2626154
4329-04-8
79EI469B7D
UNII-79EI469B7D
ETHANE, 2,2-BIS(p-PROPOXYPHENYL)-1,1,1-TRICHLORO-
DTXSID40195808
3-06-00-05437 (Beilstein Handbook Reference)
ETHANE, 1,1,1-TRICHLORO-2,2-BIS(P-PROPOXYPHENYL)-
BENZENE, 1,1'-(2,2,2-TRICHLOROETHYLIDENE)BIS(4-PROPOXY-
DTXCID40118299
Q27266755