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Acetylpyrazine

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Identification
Molecular formula
C6H6N2O
CAS number
22047-25-2
IUPAC name
1-pyrazin-2-ylethanone
State
State

At room temperature, Acetylpyrazine is in a solid state, often found in crystalline form.

Melting point (Celsius)
67.00
Melting point (Kelvin)
340.15
Boiling point (Celsius)
233.00
Boiling point (Kelvin)
506.15
General information
Molecular weight
122.13g/mol
Molar mass
122.1250g/mol
Density
1.1208g/cm3
Appearence

Acetylpyrazine appears as a light yellow to pale yellow crystalline solid. It is known for its distinct nutty, cracker-like odor, which makes it quite useful in flavoring applications.

Comment on solubility

Solubility of 1-pyrazin-2-ylethanone

1-pyrazin-2-ylethanone, also known as 2-acetylpyrazine, showcases unique solubility characteristics that can be quite intriguing.

Solubility Profile

This compound demonstrates:

  • Good solubility in organic solvents such as ethanol, methanol, and acetone.
  • Limited solubility in water, which is typical for many organic compounds containing nitrogen heterocycles.

Specifically, studies indicate that:

  • At room temperature, the solubility of 1-pyrazin-2-ylethanone in water is low, allowing just a fraction of the compound to dissolve.
  • With an increase in temperature, its solubility in water may slightly improve, but it remains relatively low compared to other polar compounds.

In conclusion, the solubility of 1-pyrazin-2-ylethanone is largely governed by its structural characteristics, exhibiting strong affinities for organic solvents while being considerably less soluble in aqueous solutions.

Interesting facts

Interesting Facts About 1-Pyrazin-2-ylethanone

1-Pyrazin-2-ylethanone, often abbreviated as PEA, is a fascinating chemical compound that belongs to the family of heterocyclic aromatic compounds. Here are some intriguing aspects:

  • Structure and Composition: This compound consists of a pyrazine ring, which is a six-membered aromatic ring containing two nitrogen atoms at non-adjacent positions. The addition of an ethanone group (ketone) enhances its reactivity and versatility in organic reactions.
  • Applications in Synthesis: 1-Pyrazin-2-ylethanone is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows for modifications that can lead to the development of new drug candidates.
  • Biological Activity: Compounds related to pyrazine rings have demonstrated significant biological activities. For instance, studies have shown that derivatives of pyrazine can exhibit anti-inflammatory, antimicrobial, and anticancer properties. This creates potential avenues for research and drug development.
  • Flavor and Fragrance Industry: Pyrazine derivatives, including 1-Pyrazin-2-ylethanone, are sometimes utilized in the food industry to create flavors and aromas. Their distinct scent profiles can enhance the sensory experience of various food products.
  • Chemical Reactivity: The ketone functional group present in this compound makes it susceptible to nucleophilic attacks, allowing for numerous chemical reactions that can be harnessed in synthetic organic chemistry.

In summary, 1-Pyrazin-2-ylethanone exemplifies the intricacies of organic chemistry through its unique structure, diverse applications, and potential biological significance. As research continues, we may uncover even more applications for this compound, leading to breakthroughs in pharmaceuticals and materials science.

Synonyms
Acetylpyrazine
2-ACETYLPYRAZINE
22047-25-2
Ethanone, 1-pyrazinyl-
1-pyrazin-2-ylethanone
1-(pyrazin-2-yl)ethan-1-one
1-Pyrazinylethanone
Pyrazin-1-ylethan-1-one
Ethanone, l-pyrazinyl-
FEMA No. 3126
GR391IBU5C
DTXSID5047085
NSC-72374
DTXCID3027085
CHEBI:145236
RefChem:85006
244-753-5
Methyl pyrazinyl ketone
1-(pyrazin-2-yl)ethanone
MFCD00006134
Ketone, methyl pyrazinyl
Ethanone, 1-(2-pyrazinyl)-
1-pyrazin-2-yl-ethanone
Pyrazine der.
1-(2-Pyrazinyl)ethanone
1-Pyrazin-2-ylethan-1-one
2-acetyl pyrazine
acetyl pyrazine
EINECS 244-753-5
1-pyrazinyl-ethanone
NSC 72374
L-Pyrazinyl-Ethanone
Acetylpyrazine, 97%
2-acetyl-1,4-diazine
AI3-34445
UNII-GR391IBU5C
1-(2-pyrazinyl)-ethanone
1-(pyrazin-2-yl)-ethanone
SCHEMBL78340
1-(2-Pyrazinyl)ethanone #
ACETYLPYRAZINE [FHFI]
1-(2-pyrazinyl)-1-ethanone
orb1301659
SCHEMBL1894555
SCHEMBL5269448
SCHEMBL7264943
2-ACETYLPYRAZINE [FCC]
CHEMBL3188662
SCHEMBL29993937
FEMA 3126
METHYL 2-PYRAZINYL KETONE
BCP29214
MSK15400
NSC72374
Tox21_302309
AC7524
BBL037027
s6261
SBB006738
STL560136
AKOS000265506
AB00602
AC-3203
CS-W007692
FA35640
HY-W007692
PS-5458
2-Acetylpyrazine, >=99%, FCC, FG
NCGC00256085-01
SY004986
CAS-22047-25-2
DB-001327
DB-313499
A0988
NS00012989
EN300-67311
47A252
F002741
Q15726062
F2158-1508
Z513735920
2-Acetylpyrazine pound>>1-Pyrazinylethanone pound>>1-pyrazin-2-yl-ethanone