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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S2
CAS number
64485-93-4
IUPAC name
1-tert-butoxycarbonyloxyethyl 7-[[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
State
State

At room temperature, cefotaxime is found in a solid state. It is typically available in powder form for use in pharmaceutical preparations, particularly for intravenous or intramuscular injections.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
274.40
Boiling point (Kelvin)
547.55
General information
Molecular weight
477.51g/mol
Molar mass
477.5050g/mol
Density
1.2300g/cm3
Appearence

Cefotaxime is a white to slightly yellowish crystalline powder. It is generally odorless and is relatively stable when stored under appropriate conditions. Its appearance can vary slightly depending on the degree of purification and processing.

Comment on solubility

Solubility of 1-tert-butoxycarbonyloxyethyl 7-[[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

The solubility characteristics of the compound C16H17N5O7S2 are of significant interest, particularly given its complex structure and potential applications. Understanding its solubility can be crucial for formulating effective delivery systems and assessing bioavailability.
Below are some key points regarding its solubility:

  • Solvent Dependence: The compound may exhibit varying solubility in different solvents. Polar protic solvents like water or methanol may dissolve polar regions of the molecule more effectively, while non-polar solvents may not.
  • pH Influence: The solubility may also be influenced by the pH of the solution, particularly due to the presence of functional groups that can ionize in acidic or basic conditions.
  • Temperature Impact: As with many organic compounds, increasing temperature typically enhances solubility, allowing for more efficient dissolution and potential applications in thermally influenced pathways.
  • Interaction with Biological Systems: For pharmaceutical applications, solubility in biological fluids is paramount. The amphipathic nature suggested by its structure may impart pleasing solubility characteristics in lipid-rich environments.

In conclusion, understanding the solubility of C16H17N5O7S2 is essential for its functional applications in both laboratory and industrial settings. Proper characterization of its solubility will provide essential insights into its behavior in different environments.

Interesting facts

Interesting Facts about 1-tert-butoxycarbonyloxyethyl 7-[[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

This fascinating compound, often abbreviated for ease of reference, belongs to a class of chemicals known for their biological activities. Here are some intriguing highlights:

  • Complex Structure: The molecule features a bicyclic architecture, incorporating a thiazole and various functional groups that contribute to its potential reactivity and biological interaction.
  • Pharmaceutical Relevance: Compounds like this one are of particular interest in drug development. Its intricate design hints at possible applications in treating bacterial infections.
  • Mechanism of Action: The presence of the 5-thia-1-azabicyclo system suggests mechanisms akin to existing antibiotics, impacting the bacterial cell wall synthesis.
  • Synthetic Pathways: This molecule can be synthesized through several methods, involving strategic manipulation of functional groups and careful consideration of stereochemistry.
  • Research & Development: Scientists are constantly exploring modifications to compounds like this to enhance their efficacy and reduce side effects in pharmaceutical applications.

As one delves deeper into the world of organic chemistry and pharmaceutical sciences, compounds like 1-tert-butoxycarbonyloxyethyl 7-[[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate epitomize the complexity and ingenuity that drives drug discovery and development.

In the words of a renowned chemist, *"The true beauty of chemistry lies not just in the compounds we create, but in the potential they hold to alter lives."*