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Carteolol

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Identification
Molecular formula
C16H24NO4
CAS number
51781-21-6
IUPAC name
1-(tert-butylamino)-3-[2-(tetrahydrofuran-2-ylmethoxy)phenoxy]propan-2-ol
State
State

Cateolol is a crystalline solid at room temperature.

Melting point (Celsius)
184.00
Melting point (Kelvin)
457.00
Boiling point (Celsius)
550.60
Boiling point (Kelvin)
823.80
General information
Molecular weight
292.37g/mol
Molar mass
292.3840g/mol
Density
1.1885g/cm3
Appearence

Cateolol typically appears as a white or off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 1-(tert-butylamino)-3-[2-(tetrahydrofuran-2-ylmethoxy)phenoxy]propan-2-ol (C16H24NO4)

The solubility of 1-(tert-butylamino)-3-[2-(tetrahydrofuran-2-ylmethoxy)phenoxy]propan-2-ol in various solvents can be influenced by its structural attributes and the functional groups present. To understand its solubility characteristics, consider the following points:

  • Hydrophobic and Hydrophilic Balance: The compound possesses both hydrophobic (tert-butyl and phenyl groups) and hydrophilic (alcohol and ether functionalities) characteristics, suggesting that it may have moderate solubility in polar solvents such as water and lower solubility in nonpolar solvents.
  • Influence of Tetrahydrofuran Unit: The presence of the tetrahydrofuran moiety can enhance solubility in organic solvents due to its ring structure, allowing for better interactions with both polar and nonpolar environments.
  • Alcohol Group: The hydroxyl functional group typically promotes solubility in water, making the compound likely to be more soluble in aqueous solutions when compared to purely hydrophobic compounds.

Overall, the solubility can be expected to be influenced significantly by the specific solvent environment and temperature. It's essential to conduct experimental assays to determine precise solubility values in various solvents to understand its applicability in formulations.

Interesting facts

Interesting Facts About 1-(tert-butylamino)-3-[2-(tetrahydrofuran-2-ylmethoxy)phenoxy]propan-2-ol

This unique compound is not only fascinating due to its complex structure but also stands out for its potential applications in various scientific fields. Here are some key points worth noting:

  • Structural Complexity: The compound features a tert-butylamino group, which is known for imparting stability and hydrophobic character to the molecule. This property is particularly beneficial for drug design and development.
  • Tetrahydrofuran Component: The inclusion of a tetrahydrofuran moiety introduces a cyclic ether into the compound. This can enhance its ability to interact with biological membranes, making it a compelling candidate for pharmacological exploration.
  • Phenoxy Group Influence: The presence of a phenoxy group is significant. It can contribute to the compound's reactivity and can also serve as a pharmacophore—an essential part of the molecule that enables it to interact with a biological target.
  • Potential Biological Applications: Compounds with similar structures have been studied for their roles in various therapeutic areas, including anti-cancer and anti-inflammatory research. Its unique arrangement could lead to discovering new medicinal properties.
  • Drug Delivery Systems: The amphiphilic nature of this compound may allow it to act as a surfactant in drug delivery systems, enhancing the solubility and bioavailability of other pharmacologically active agents it delivers.

As noted by several researchers in the field:

“The design of complex molecules like this compound offers insights into the intricate balance between structure and biological activity, paving the way for innovative therapeutic strategies.”

In essence, 1-(tert-butylamino)-3-[2-(tetrahydrofuran-2-ylmethoxy)phenoxy]propan-2-ol exemplifies the exciting interplay between organic chemistry and medicinal science, making it a valuable target for future investigations and applications.

Synonyms
Bufetolol
53684-49-4
Bufetolol [INN]
Bufetololum
Bufetololum [INN-Latin]
UNII-WS1467RT9Z
WS1467RT9Z
DTXSID9057763
1-(tert-butylamino)-3-[2-(oxolan-2-ylmethoxy)phenoxy]propan-2-ol
BUFETOLOL [MI]
Y 6124 [AS HYDROCHLORIDE]
BUFETOLOL [WHO-DD]
Y 6124 FREE BASE
Y-6124 FREE BASE
DTXCID0031552
Bufetololum (INN-Latin)
1-(tert-Butylamino)-3-(o-((tetrahydrofurfuryl)oxy)phenoxy)-2-propanol
Y 6124 (AS HYDROCHLORIDE)
2-Propanol, 1-(1,1-(dimethylethyl)amino)-3-(2-((tetrahydro-2-furanyl)methoxy)phenoxy)-
1-tert-butylamino-3-(o-(tetrahydrofurfuryloxy)phenoxy)-2-propanol
bufetololo
SCHEMBL78862
CHEMBL347830
CHEBI:135376
Tox21_113888
1-tert-butylamino-3-(2-tetrahydrofurfuryloxy-phenoxy)-propan-2-ol
AKOS040745637
1-[(2-Methyl-2-propanyl)amino]-3-[2-(tetrahydro-2-furanylmethoxy) phenoxy]-2-propanol
NCGC00261968-01
CAS-53684-49-4
HY-121005
CS-0078924
Q15634021