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Zolpidem

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Identification
Molecular formula
C17H17N3O1S1
CAS number
82626-48-0
IUPAC name
10-(1-methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine
State
State

At room temperature, Zolpidem is typically in solid form as it is normally utilized as a medication in tablet form. It is not commonly available or used as a simple chemical reagent in a basic state.

Melting point (Celsius)
192.60
Melting point (Kelvin)
465.75
Boiling point (Celsius)
385.00
Boiling point (Kelvin)
658.15
General information
Molecular weight
307.40g/mol
Molar mass
307.4010g/mol
Density
1.2651g/cm3
Appearence

Zolpidem typically presents as white to off-white crystalline powders. It is not available in a pure form for general use but is found in dosage forms as a medication.

Comment on solubility

Solubility of 10-(1-methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine

The solubility of 10-(1-methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine can be a complex consideration due to its unique structure. Here are some important points regarding its solubility:

  • Polarity: The presence of functional groups such as piperidine can contribute to the overall polarity of the compound, potentially increasing solubility in polar solvents.
  • Solvent Compatibility: It is likely to have varying solubility in different solvents. For example:
    • Water: Likely low solubility
    • Organic solvents: More soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO)
  • Temperature Effects: As with many compounds, solubility can increase with temperature, which enhances the kinetic energy of molecules.
  • Crystallinity: The crystalline form may affect solubility; amorphous forms tend to dissolve easier than crystalline forms.

In summary, while 10-(1-methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine may not be soluble in water, it shows promise for solubility in organic solvents, influenced by factors such as temperature and the presence of polar groups. Understanding these factors is crucial for applications in pharmacology and material science.

Interesting facts

Interesting Facts about 10-(1-Methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine

10-(1-Methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine is a compound of considerable interest in the field of medicinal chemistry. Its unique structure boasts both a thiochromene and a pyridine ring, which contribute to its biological activity and potential applications. Here are some captivating facts about this intriguing compound:

  • Complex Structure: The compound contains a piperidine moiety, which is known for enhancing the solubility and membrane permeability of compounds, making it attractive for drug design.
  • Targeted Actions: Compounds in this class have shown promising results in targeting various biological pathways, which may lead to treatments for neurological disorders.
  • Research Interest: Its unique structure allows it to be studied for potential activity against diseases such as cancer and neurodegenerative conditions, reflecting the ongoing search for effective therapies.
  • Synthetic Versatility: The synthesis of this compound involves multi-step reactions, showcasing the creativity required in synthetic organic chemistry to create complex molecules with specific functionalities.
  • Potential for Pharmacological Application: Preliminary studies suggest that derivatives of thiochromeno[3,2-b]pyridine may exhibit antimicrobial, anti-inflammatory, and antioxidant properties.

As researchers continue to explore the vast landscape of chemical compounds, 10-(1-methyl-4-piperidylidene)thiochromeno[3,2-b]pyridine presents a fascinating intersection of structure and potential applicability in therapeutic settings. In the words of a renowned chemist, "Every molecule has a story to tell; it's our job to uncover its secrets." This compound is undoubtedly another chapter in that story.

Synonyms
HCC6FW5Z4U
UNII-HCC6FW5Z4U
10-(N-Methylpiperidyliden-4)-1-azathioxanthene
47124-87-8
10-(1-Methyl-4-piperidinylidene)-10H-(1)benzothiopyrano(3,2-b)pyridine
10H-(1)Benzothiopyrano(3,2-b)pyridine, 10-(1-methyl-4-piperidinylidene)-
SCHEMBL9212993
DTXSID40274925
10-(1-methylpiperidin-4-ylidene)thiochromeno[3,2-b]pyridine