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Methdilazine

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Identification
Molecular formula
C18H20N2S
CAS number
1982-37-2
IUPAC name
10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine
State
State

At room temperature, Methdilazine is in a solid state.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
326.48g/mol
Molar mass
326.4770g/mol
Density
1.2047g/cm3
Appearence

It is typically described as a white or off-white crystalline powder.

Comment on solubility

Solubility of 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine

The solubility of 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine is an interesting topic due to its implications in various fields, particularly in pharmaceuticals. Understanding its solubility can provide insights into its behavior in biological systems.

Factors Affecting Solubility

Several factors can influence the solubility of this compound:

  • Polarity: The presence of polar functional groups within the compound can enhance its solubility in polar solvents, whereas a non-polar structure may favor solubility in non-polar solvents.
  • Temperature: Generally, increasing the temperature can increase solubility for most solids; therefore, understanding the temperature dependency is crucial.
  • pH Level: The pH of the solution can greatly affect the ionization of functional groups, potentially altering solubility.

Solubility Profile

While definitive solubility data for 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine is not widely reported, it is anticipated to exhibit:

  • Limited solubility in water due to its large, complex structure.
  • Better solubility in organic solvents like ethanol or dimethyl sulfoxide (DMSO) where it can interact more favorably.

In conclusion, the solubility of 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine can vary significantly based on the conditions of the environment. Thus, identifying suitable solvents and optimizing conditions for its dissolution is essential for applications in research and drug formulation.

Interesting facts

Exploring 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine

10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine is a fascinating compound that attracts interest in both medicinal chemistry and pharmacology. It belongs to the phenothiazine class, which has proven to be pivotal in the development of antipsychotic medications. Here are some key points that underline the significance of this compound:

  • Pharmacological Relevance: Phenothiazines have historically been used to treat various mental illnesses, primarily schizophrenia. This compound may exhibit similar properties that can be explored for therapeutic uses.
  • Structural Complexity: The integration of a 1-methylpyrrolidin moiety enhances its bioactivity. This structural modification can influence how the compound interacts with its biological targets, potentially improving potency and specificity.
  • Rise of Dual-Action Compounds: Research is increasingly focusing on compounds that combine multiple pharmacological actions. This compound’s unique structure might enable it to act on multiple pathways, which could lead to innovative treatment options.
  • Future Research Dimensions: Given its structure and potential activity, ongoing studies could focus on understanding the compound's mechanism of action, side effects, and efficacy in clinical settings.

As we delve deeper into the exploration of compounds like 10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine, it is crucial to consider the intricate dance of chemistry and biology that unfolds. As a chemistry student, it’s exciting to think, as Thomas Edison once said, “The most certain way to succeed is always to try just one more time.” The implications of such compounds in the therapeutic landscape could be transformative!

Synonyms
METHDILAZINE
1982-37-2
Methdilazinum
Tacazyl
Metodilazina
Tacryl
Methdilazinum [INN-Latin]
Metodilazina [INN-Spanish]
Dilosyn
metdilazina
NCI-C60720
EINECS 217-841-6
UNII-4Q13LY9Z8X
10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine
4Q13LY9Z8X
CHEBI:6823
10-((1-Methyl-3-pyrrolidinyl)methyl)phenothiazine
Methdilazine [USP:INN:BAN]
10H-Phenothiazine, 10-((1-methyl-3-pyrrolidinyl)methyl)-
DTXSID6023282
10-[(1-Methyl-3-Pyrrolidinyl)methyl]phenothiazine
Phenothiazine, 10-((1-methyl-3-pyrrolidinyl)methyl)-
10H-Phenothiazine, 10-[(1-methyl-3-pyrrolidinyl)methyl]-
Methdilazinum (INN-Latin)
Metodilazina (INN-Spanish)
METHDILAZINE (MART.)
METHDILAZINE [MART.]
Methdilazine (USP:INN:BAN)
Phenothiazine, 10-[(1-methyl-3-pyrrolidinyl)methyl]-
10-((1-methylpyrrolidin-3-yl)methyl)-10H-phenothiazine
10-((1-Methyl-3-pyrrolidinyl)methyl)phenothiazine monohydrochloride
DTXCID903282
R06AD04
217-841-6
Tacaryl
10-[(1-Methylpyrrolidin-3-yl)methyl]phenothiazine
Methdilazine (INN)
Methodilazine
METHDILAZINE [INN]
NSC169091
10-[(1-Methyl-3-pyrrolidinyl)methyl]phenothiazine; MJ 5022
Tacaryl (TN)
METHDILAZINE (200 MG)
Dilosyn (Salt/Mix)
Disyncram (Salt/Mix)
Disyncran (Salt/Mix)
METHDILAZINE [MI]
METHDILAZINE [VANDF]
METHDILAZINE [WHO-DD]
SCHEMBL121507
GTPL7231
10-((1-methyl-3-pyrrolidinyl)methyl)-10H-phenothiazine
CHEMBL1200959
BDBM81470
METHDILAZINE [ORANGE BOOK]
HY-B1690
10H-Phenothiazine, tannate (5:1)
CAS_14677
NSC_14677
NSC244191
PDSP1_000149
PDSP2_000148
DB00902
NSC-244191
DA-69430
NCI60_001351
CS-0013673
NS00026450
C07175
D04979
EN300-18552794
L001130
SR-01000944494
Q6665709
SR-01000944494-1
10-[(1-Methyl-3-pyrrolidinyl)methyl]-10H-phenothiazine #