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Clotrimazole

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Identification
Molecular formula
C22H17ClN2O
CAS number
23593-75-1
IUPAC name
10-(3-chloroallyl)-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
State
State

Clotrimazole is in a solid state at room temperature. As a pharmaceutical compound, it is often formulated in creams and solutions, but its raw form is a solid powder.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
441.50
Boiling point (Kelvin)
714.65
General information
Molecular weight
344.84g/mol
Molar mass
344.8450g/mol
Density
1.2530g/cm3
Appearence

Clotrimazole appears as a white crystalline powder. It is typically odorless and has a mild, bitter taste.

Comment on solubility

Solubility of 10-(3-chloroallyl)-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The solubility of 10-(3-chloroallyl)-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol is a notable aspect to consider due to its unique structural features. Here are some insights on its solubility profile:

  • Organic Solvents: Given its complex molecule, this compound is likely to exhibit solubility in a range of organic solvents. Common solvents may include ethanol, acetone, and chloroform due to polar interactions.
  • Water Solubility: The presence of the hydroxyl (-OH) group suggests some potential for solubility in water; however, the overall hydrophobic nature of its structure may limit this significantly.
  • Influence of Substituents: The 3-chloroallyl and methyl groups influence the solubility characteristics, possibly enhancing solubility in non-polar solvents while decreasing solubility in polar solvents.

Overall, it is essential to test solubility in specific solvents to determine the practical applications and behavior of this compound in various environments. As always, empirical assessment is key, and experiments can yield valuable insights into its solubility dynamics.

Interesting facts

Interesting Facts about 10-(3-chloroallyl)-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

This unique compound is situated within the fascinating realm of organic chemistry, showcasing an intricate structure that captivates both scientists and students alike. Here are some compelling points about this compound:

  • Niche Applications: The versatile nature of this compound makes it a candidate for research in medicinal chemistry and agrochemicals, potentially opening new pathways for drug development.
  • Complex Structure: Its intricate tricyclic framework, combined with the azatricycle arrangement, represents a unique structural challenge that invites further exploration in synthetic organic chemistry.
  • Reactive Functional Groups: The presence of both chloro and allyl groups indicates that this compound may be subject to various chemical reactions, making it interesting for synthetic applications.
  • Biological Activity: Preliminary studies suggest that similar compounds might exhibit significant biological activity, including antimicrobial and anticancer properties, positioning this compound as a noteworthy candidate for further biological evaluation.
  • Synthetic Routes: The complexity of its synthesis can lead to discussions about various synthetic strategies, potentially introducing students to innovative organic synthesis techniques.

In summary, 10-(3-chloroallyl)-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol is not just a compound with an elaborate name; it embodies a realm of possibilities within chemistry, beckoning for further exploration and research.