Skip to main content

Erythromycin

ADVERTISEMENT
Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[10-acetoxy-6-[5-(4-acetoxy-6-methyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
State
State

At room temperature, erythromycin is typically found as a solid crystalline powder.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
306.00
Boiling point (Kelvin)
579.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2400g/cm3
Appearence

Erythromycin is a white or slightly yellow, crystalline powder. It is a substance that tends to absorb moisture (hygroscopic) and is known to have a slightly bitter taste.

Comment on solubility

Solubility of 10-acetoxy-6-[5-(4-acetoxy-6-methyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl propanoate (C37H67NO13)

The solubility of this complex compound is an interesting subject due to its intricate molecular structure and functional groups. Analyzing the solubility behavior can reveal valuable insights:

  • Nonpolar Components: The presence of long hydrocarbon chains contributes to hydrophobic interactions, suggesting limited solubility in polar solvents like water.
  • Polar Functional Groups: Conversely, functional groups such as hydroxyl (–OH) and acetoxy (–OCOCH3) may enhance solubility in polar solvents, promoting partial dissolution.
  • Solvent Interaction: This compound may show varying solubility based on the polar nature of the solvent used, with higher solubility in organic solvents like ethanol or methanol.

In summary, the solubility of C37H67NO13 can be best described as:

  1. Limited Solubility in Water: due to hydrophobic hydrocarbon portions.
  2. Moderate Solubility in Polar Organic Solvents: thanks to polar functional groups.

Understanding the solubility characteristics is crucial for applications in fields such as pharmaceuticals, where the bioavailability of compounds can heavily depend on their solubility profiles.

Interesting facts

Interesting Facts about 10-Acetoxy-6-[5-(4-acetoxy-6-methyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate

This complex organic compound, known for its intricate structure and unique functional groups, is a fascinating subject in the realm of synthetic chemistry. Here are some key points that highlight its significance:

  • Synthetic Potential: The compound exemplifies the potential of synthetic organic chemistry to create complex molecules that could have various applications in pharmaceuticals and materials science.
  • Functional Groups: The presence of multiple functional groups, including acetoxy, methoxy, and dimethylamino groups, opens doors for diverse chemical reactivity and potential applications.
  • Natural Product Mimicry: Its structure may bear resemblance to natural products, offering insights into bioactivity and pharmacological properties which make it a candidate for drug discovery.
  • Chirality and Stereochemistry: The tetrahydropyran rings in its backbone introduce important stereochemical aspects that are essential in determining the biological activity of similar compounds.
  • Research Opportunities: This molecule presents numerous opportunities for further research, including studying its interaction with biological systems and its potential therapeutic effects.

In summary, 10-acetoxy-6-[5-(4-acetoxy-6-methyl-5-propanoyloxy-tetrahydropyran-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate stands out not just for its chemical complexity but also for the potential applications it could hold. Its study could pave the way for advancements in various fields, from medicinal chemistry to agrochemicals.