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Camptothecin

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Identification
Molecular formula
C20H16N2O4
CAS number
7689-03-4
IUPAC name
10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
State
State

At room temperature, camptothecin is in a solid state, generally found as a crystalline powder.

Melting point (Celsius)
265.00
Melting point (Kelvin)
538.15
Boiling point (Celsius)
334.60
Boiling point (Kelvin)
607.75
General information
Molecular weight
348.35g/mol
Molar mass
348.3520g/mol
Density
1.2300g/cm3
Appearence

Camptothecin is typically a pale yellow crystalline solid. It is poorly soluble in water and shows fluorescence under ultraviolet light.

Comment on solubility

Solubility of 10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The solubility of 10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol (C20H16N2O4) can be quite complex due to its unique structure and functional groups. Understanding the solubility characteristics can be crucial for its applications in various fields.

Here are some key points regarding its solubility:

  • Polarity: The compound contains both hydrophilic (the hydroxyl group, -OH) and hydrophobic (the hydrocarbon chains) regions, which may influence its solubility in different solvents.
  • Solvent Compatibility: It is expected to have varying degrees of solubility in:
    • Polar solvents: such as water and alcohols, due to the presence of the hydroxyl group.
    • Nonpolar solvents: such as hydrocarbons, where the bulk of its structure is more compatible.
  • Temperature Influence: Like many organic compounds, solubility may increase with temperature, allowing better interaction with solvents.
  • Concentration Effects: At higher concentrations, solubility can be affected by aggregation or crystallization phenomena.

Overall, while precise solubility data may be limited, the structural characteristics of 10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol suggest that it possesses a degree of versatility in solubility, making it potentially useful across various chemical applications.

Interesting facts

Interesting Facts about 10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The compound known as 10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol is a fascinating and complex molecule in the realm of organic chemistry. Here are some intriguing aspects:

  • Nomenclature Complexity: The IUPAC name of this compound reflects its intricate structure. It includes multiple functional groups and describes the various aliphatic and cyclic components present in the molecule.
  • Structural Features: This compound is part of the azatricyclo family, which introduces a nitrogen atom into an otherwise carbon-only framework, altering its properties and reactivity.
  • Potential Applications: Compounds with similar frameworks are often studied for their potential in medicinal chemistry due to their unique interactions with biological systems.
  • Reactivity: The presence of allyl and hydroxyl groups renders this compound a candidate for various chemical reactions, including nucleophilic substitutions and electrophilic additions.
  • Research Interest: Scientists are intrigued by the structural diversity of such tricyclic compounds, as they can lead to novel synthetic pathways and materials.

The study of 10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol not only enhances our understanding of complex organic structures but also paves the way for innovative applications in pharmaceuticals and material science.

Synonyms
SKF-10,047
Alazocine
N-Allylnormetazocine
10-allyl-1,13-dimethyl-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-4-ol
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-allyl-6,11-dimethyl-
CHEMBL274099
7619-35-4
SKF 10047
825594-24-9
1,13-dimethyl-10-prop-2-enyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
WIN 19631
SKF10047
Lopac0_000107
SCHEMBL20348443
6,11-Dimethyl-3-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol
CHEBI:228203
DTXSID301018249
BDBM50009063
CCG-204202
SKF 10,047
SMP1_000010
NCGC00015003-03
NCGC00015003-04
NCGC00162063-01
NCGC00162063-02
(+)3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
3-Allyl-8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocinium