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Ibogaine hydrochloride

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Identification
Molecular formula
C20H27ClN2O
CAS number
103740-73-6
IUPAC name
10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride
State
State

At room temperature, ibogaine hydrochloride is a solid. It is commonly encountered in its salt form for chemical and pharmacological studies.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
273.15
Boiling point (Kelvin)
546.30
General information
Molecular weight
375.91g/mol
Molar mass
375.9100g/mol
Density
1.2000g/cm3
Appearence

Ibogaine hydrochloride typically appears as a crystalline powder. The color can vary from white to off-white or pale yellow. The compound is usually odorless, but can have a faint, characteristic smell.

Comment on solubility

Solubility of 10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride

The compound 10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride exhibits intriguing solubility characteristics that warrant attention. Understanding the solubility of this compound is crucial for its potential applications in chemical and pharmaceutical fields.

General Solubility Characteristics

  • Polarity: The presence of ionic chloride suggests that the compound may be more soluble in polar solvents.
  • Implications of Structure: The complex structure, including the azepine functional group, can influence how readily it dissolves in various solvents.
  • Solvent Interaction: Solubility may be significantly increased in solvents capable of hydrogen bonding, like water and alcohols.

Given its ionic nature, one might observe that 10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium tends to dissociate in aqueous solutions, making it potentially soluble. However, due to the influence of the methoxy group, the overall solubility can vary depending on the specific environmental conditions and the polarity of the solvent used.

Practical Considerations

  • The solubility profile in water: Likely moderate due to the balance of polar and non-polar characteristics.
  • Effect of temperature: Solubility might increase with higher temperatures, as is typical for many compounds.
  • Interaction with other solutes: The presence of salts or organic compounds can also alter solubility, demonstrating the compound's complex behavior in different mixtures.

In conclusion, the solubility of 10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride is an essential aspect to consider for its application and functionality. Understanding this property can reveal much about the compound’s potential uses and limitations.

Interesting facts

Exploring the Unique World of 10-Methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium; Chloride

This intriguing compound, known as 10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium; chloride, holds a fascinating space in the realm of chemical science due to its complex structure and potential applications.

1. Structural Marvel

The compound features a unique bicyclic indole framework combined with a hexahydroazepine ring. This intricate molecular configuration contributes to its distinct properties. Key features include:

  • Indole moiety: A core feature in many biologically active compounds.
  • Hexahydroazepine: Imparts stability and offers a site for further chemical reaction.
  • Methoxy group: Enhances solubility and may affect pharmacological activity.

2. Potential Biological Significance

Compounds that feature the indole structure are often linked to a variety of biological activities. Here are a few noteworthy points:

  • Indoles are frequently found in nature, forming the backbone of many natural products, including neurotransmitters like serotonin.
  • This particular compound’s structure suggests it could participate in interesting interactions with biological targets.
  • Research into related compounds has indicated potential use in fields such as medicinal chemistry and drug discovery.

3. The Role of Chloride

The presence of the chloride ion not only helps in stabilizing the molecule but can also influence its reactivity profile. Chloride ions are known to:

  • Act as a counterion that can facilitate solubility in various solvents.
  • Participate in nucleophilic substitution reactions, potentially leading to novel derivatives.

4. Applications in Research

This compound is of interest mainly in synthetic organic chemistry and pharmacology. Ongoing studies may explore:

  • Its potential as a scaffold for drug design.
  • Interactions with various biological systems, paving the way for future therapeutic developments.
  • Applications in material science due to its unique electronic and structural properties.

In conclusion, 10-methoxy-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium; chloride offers a wealth of opportunities for further investigation. As scientists continue to explore its properties and potential applications, this compound exemplifies the endless possibilities offered by the chemical universe.

Synonyms
1,2,3,4,5,6-Hexahydro-10-methoxy-azepino(4,5-b)indole hydrochloride
15923-44-1
AZEPINO(4,5-b)INDOLE, 1,2,3,4,5,6-HEXAHYDRO-10-METHOXY-, MONOHYDROCHLORIDE