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Harmaline hydrochloride

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Identification
Molecular formula
C13H15ClN2O
CAS number
386-97-0
IUPAC name
10-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride
State
State

At room temperature, harmaline hydrochloride is in a crystalline solid state. Its stability is compromised by exposure to moisture and light, and it should be stored in a cool, dry place in a well-sealed container.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
120.00
Boiling point (Kelvin)
393.15
General information
Molecular weight
248.75g/mol
Molar mass
248.7530g/mol
Density
1.2200g/cm3
Appearence

Harmaline hydrochloride appears as a pale yellow crystalline powder. It is sensitive to light and may darken over time if not stored properly. The crystals are typically small, prismatic, and can appear slightly hygroscopic in nature.

Comment on solubility

Solubility of 10-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride

The solubility of 10-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride is influenced by various factors, particularly its ionic nature and molecular structure. This compound, being a quaternary ammonium salt, exhibits certain characteristics regarding solubility:

  • Water Solubility: As a chloride salt, it is likely to be soluble in water due to the dissociation of the chloride ions which facilitates interaction with water molecules.
  • Solvent Compatibility: It may show variable solubility in organic solvents, depending on their polarity. Factors such as temperature and solvent choice can dramatically alter solubility.
  • Influence of pH: The solubility can also be impacted by the pH of the solution, as changes in ionization state can affect its interaction with solvents.

In conclusion, while 10-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride may demonstrate good solubility in aqueous environments, it’s essential to consider the specific solvent system when assessing its overall solubility profile. As always, conducting empirical solubility tests is invaluable for practical applications.

Interesting facts

Exploring 10-Methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium Chloride

The compound 10-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium;chloride belongs to a fascinating category of organic compounds known as alkaloids. Alkaloids are typically derived from plant sources and are famed for their complex structures and diverse biological activities.

Key Features

  • Diverse Applications: Alkaloids like this compound often exhibit various biological properties, including anti-inflammatory, analgesic, and even anti-cancer effects, making them significant in medicinal chemistry.
  • Structural Complexity: The intricate ring structure of this compound suggests potential challenges in synthesis, yet this complexity is often associated with enhanced biological activity and specificity.
  • Potential in Drug Development: The unique arrangement of nitrogen and carbon atoms in its structure could inspire new drug candidates, targeting specific biological pathways.

As a chemistry student or a scientist, understanding the structure of compounds like this can be a gateway to both synthetic and natural product chemistry. It's essential to appreciate how *molecular modifications* can lead to vastly different properties and functionalities. Researchers often explore these alterations to improve the efficacy and reduce side effects of potential pharmaceuticals.

In conclusion, the study of 10-methoxy-6-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indol-6-ium chloride opens up exciting avenues in medicinal chemistry and organic synthesis, reminding us of the *intricate dance* of atoms and their profound effects on health and disease.

Synonyms
15923-43-0
1,2,3,4,5,6-Hexahydro-10-methoxy-6-methyl-azepino(4,5-b)indole hydrochloride
Azepino(4,5-b)indole, 1,2,3,4,5,6-hexahydro-10-methoxy-6-methyl-, monohydrochloride