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Cholecalciferol

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Identification
Molecular formula
C27H44O
CAS number
67-97-0
IUPAC name
10,13-dimethyl-17-[(4R)-1,4,5-trimethylhexyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
State
State

Cholecalciferol is typically found in solid form at room temperature, appearing as a crystalline powder. It is stable when stored away from light and air, as it is sensitive to oxidation and photodegradation.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
148.00
Boiling point (Kelvin)
421.15
General information
Molecular weight
384.64g/mol
Molar mass
384.6400g/mol
Density
1.1600g/cm3
Appearence

Cholecalciferol is a colorless, crystalline substance. It may appear as an amorphous or crystalline powder that is often used in its pure form for pharmaceutical and dietary purposes. Being sensitive to light and air, it may degrade if not stored properly. The compound's crystalline nature gives it a somewhat shiny appearance under light.

Comment on solubility

Solubility Assessment

The solubility of 10,13-dimethyl-17-[(4R)-1,4,5-trimethylhexyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol can be influenced by various factors due to its complex structure.

  • Polarity: This compound features multiple methyl groups that may lower its polarity, suggesting a higher tendency for solubility in non-polar solvents.
  • Functional Groups: The presence of an alcohol (-OH) group typically enhances solubility in polar solvents like water, whereas the bulkiness introduced by the hydrocarbon chains may reduce this effect.
  • Temperature Dependency: Solubility can also vary with changes in temperature, with increased temperatures generally promoting solubility for solid compounds.
  • Interaction with Solvents: Compatibility with solvents can be predicted through the "like dissolves like" principle, meaning that non-polar organic solvents are likely to dissolve this compound more effectively than polar solvents.

In conclusion, due to its complex molecular structure and varying functional groups, the solubility of this compound is likely to be significant in non-polar environments while possibly facing limitations in polar environments. It's important to consider the specific conditions under which solubility is being evaluated to draw accurate conclusions.

Interesting facts

Interesting Facts about 10,13-Dimethyl-17-[(4R)-1,4,5-trimethylhexyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

This compound, often referred to in scientific literature as a steroid derivative, exhibits a fascinating structure and properties that have captured the interest of researchers and chemists alike. Here are some intriguing aspects:

  • Synthetic Origins: The compound is often synthesized for its resemblance to certain natural steroid hormones, making it a point of interest in studies relating to synthetic biology and pharmaceutical applications.
  • Structural Complexity: With its multi-ring system and substituents, this compound exemplifies the intricate designs that can arise within organic chemistry, showing the beauty of molecular architecture.
  • Potential Applications: The biosynthetic pathways and functional analogs of this compound could have implications in developing new therapies or steroids with modified biological activities.
  • Chirality: The "R" configuration at one of its chiral centers highlights how stereochemistry plays a crucial role in the activity and behavior of steroid molecules in biological systems.
  • Research Interest: Given its complex structure, it is often studied in relation to anabolic steroids and their physiological effects, leading to potential implications in medical and sports science.

As a compound that bridges the gap between organic synthesis and biological functionality, 10,13-dimethyl-17-[(4R)-1,4,5-trimethylhexyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol serves as an excellent example of how detailed inquiry into chemical structures can unravel new avenues for medical advancements.

In summation, the exploration of such compounds not only enhances our understanding of chemistry but also propels forward the frontiers of medical science and pharmacology. It is a testament to the profound connection between structure and function in organic compounds.