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Dexamethasone sodium phosphate

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Identification
Molecular formula
C22H29FO5
CAS number
55203-24-2
IUPAC name
[10,13-dimethyl-2,3-disulfonatooxy-17-(1,4,5-trimethylhexyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-6-yl] sulfate
State
State

At room temperature, Dexamethasone sodium phosphate is a crystalline solid.

Melting point (Celsius)
262.00
Melting point (Kelvin)
535.00
Boiling point (Celsius)
680.00
Boiling point (Kelvin)
953.00
General information
Molecular weight
516.41g/mol
Molar mass
516.4050g/mol
Density
1.5940g/cm3
Appearence

Dexamethasone sodium phosphate is typically encountered as a white to almost white, crystalline powder. It can appear slightly hygroscopic.

Comment on solubility

Solubility of [10,13-dimethyl-2,3-disulfonatooxy-17-(1,4,5-trimethylhexyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-6-yl] sulfate

The solubility of the compound C22H29FO5 can be characterized by several important factors:

  • Polarity: Due to the presence of sulfate and sulfonate groups, this compound is likely to be polar, which often facilitates solubility in polar solvents such as water.
  • Hydrophilic vs. Hydrophobic Components: The compound contains both hydrophilic (sulfonate and sulfate) and hydrophobic (alkyl groups) parts. This dual nature can lead to interesting solubility behavior.
  • Solvent Compatibility: The solubility will be affected by the nature of the solvent. Generally, polar solvents will dissolve polar compounds better than non-polar solvents.

In practical terms, you might observe that:

  • The compound is likely more soluble in aqueous solutions due to its ionic functional groups.
  • In organic solvents, solubility may diminish because the hydrophobic regions of the molecule could resist interactions with polar oils or solvents.

Based on the attributes of its functional groups and overall structure, it can be summarized that:

  • Aqueous solubility is favored, especially at moderate temperatures.
  • Solubility may vary widely with changes in pH and temperature.
  • Expected to show limited solubility in non-polar organic solvents.

Understanding these aspects can greatly aid in predicting the behavior of this compound in various environments and applications.

Interesting facts

Interesting Facts about 10,13-Dimethyl-2,3-disulfonatooxy-17-(1,4,5-trimethylhexyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-6-yl Sulfate

This compound, with its complex name, features a unique structure that piques the interest of chemists and biochemists alike. The presence of various functional groups contributes to its reactivity and potential applications. Here are some notable aspects:

  • Structural Complexity: The compound contains multiple methyl groups, which may influence its physical and chemical properties. Methylation often enhances lipid solubility, thereby affecting biological activity.
  • Potential Applications: Given its intricate molecular architecture, this compound may be investigated for uses in pharmaceutical development or materials science, particularly in the creation of targeted delivery systems.
  • Biological Significance: The association with cyclopenta[a]phenanthrenes suggests that this compound could be of interest in studies related to steroid receptors and hormone activity modulation.
  • Environmental Impact: Such sulfonate groups are suspected of having implications in various environmental processes. Their behavior in biological systems is crucial for understanding their environmental fate.

As one delves deeper into chemical research, compounds like this highlight the intricate dance between structure and function. As noted by renowned chemist René Dubos, “The art of medicine consists in amusing the patient while nature cures the disease.” Similarly, the study of such complex compounds often intertwines the roles of chemistry and biology, leading to fascinating discoveries!


This compound serves as a reminder of the beauty and complexity inherent in chemical sciences. Each functional group can provide a different facet of reactivity and interaction, making the world of organic chemistry endless and intriguing.