Skip to main content

Corticosterone

ADVERTISEMENT
Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
(10,13-dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl) acetate
State
State

At room temperature, corticosterone is in a solid state. As a crystalline powder, it remains stable under normal temperatures and pressures.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
346.46g/mol
Molar mass
346.4610g/mol
Density
1.2140g/cm3
Appearence

Corticosterone is a white to off-white crystalline powder. It is odorless and is generally stable under ordinary conditions of use and storage. The compound's crystalline form provides it with a distinct appearance as a powder.

Comment on solubility

Solubility of (10,13-Dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl) Acetate (C21H30O4)

The solubility of (10,13-dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl) acetate can be influenced by several factors:

  • Polarity: The presence of functional groups such as ester and ketone affects overall polarity, making the compound somewhat soluble in organic solvents.
  • Solvent Type: It is expected to exhibit moderate solubility in non-polar to moderately polar organic solvents like dichloromethane or ethanol, but limited solubility in water.
  • Temperature Effects: Solubility may increase with temperature, as is common with many organic compounds; higher temperatures often promote dissolution.

In general, the compound's complex structure and the presence of multiple functional moieties lead to variability in solubility. It is crucial to consider the specific solvent conditions when determining practical solubility for applications in synthesis and formulation.

As a rule of thumb, compounds with greater molecular weight and more extensive hydrophobic regions tend to have lower solubility in aqueous environments.

Interesting facts

Interesting Facts About 10,13-Dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl Acetate

This compound is a fascinating member of the steroid family, exhibiting several unique characteristics that make it a subject of interest in the field of chemistry and biochemistry. Here are some notable points:

  • Structural Complexity: The compound features a complex polycyclic structure, which is characteristic of many steroids. Its intricate arrangement not only contributes to its stability but also plays a crucial role in its biological activity.
  • Biological Relevance: Due to its steroidal nature, this compound may be related to various biological functions, including hormone regulation and metabolic processes. Such compounds often serve as precursors to hormones that modulate physiological responses.
  • Synthetic Applications: As a synthetic derivative, it offers exciting possibilities in medicinal chemistry. It can be a valuable lead compound for the development of therapeutics targeting specific biological pathways.
  • Research Potential: The compound's potential interactions with biological receptors make it a prime candidate for further research in pharmacology and drug design, especially in understanding the mechanisms of action of steroid-related drugs.

In summary, the study of 10,13-dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl acetate not only enhances our knowledge of complex organic compounds but also contributes to the larger field of medicinal chemistry, reflecting the dynamic nature of chemical research.

Synonyms
CHEMBL156731
DB-053954