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Estrone

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Identification
Molecular formula
C18H22O2
CAS number
53-16-7
IUPAC name
10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione
State
State

At room temperature, estrone is in a solid state.

Melting point (Celsius)
258.00
Melting point (Kelvin)
531.15
Boiling point (Celsius)
417.00
Boiling point (Kelvin)
690.15
General information
Molecular weight
270.37g/mol
Molar mass
270.3660g/mol
Density
1.2300g/cm3
Appearence

Estrone appears as a white to off-white crystalline powder. It is usually odorless.

Comment on solubility

Solubility of 10,13-Dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione (C18H22O2)

The solubility of 10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione can be characterized as relatively low in water. As a compound with a complex structure, it tends to exhibit hydrophobic properties which limit its interaction with polar solvents such as water. Instead, this compound is likely to show greater solubility in organic solvents due to its non-polar characteristics. Here are some key points to consider regarding its solubility:

  • Water Solubility: Generally low due to the hydrophobic nature of the carbon skeleton and functional groups.
  • Organic Solvents: More soluble in non-polar to moderately polar solvents such as dichloromethane, chloroform, and hexane.
  • Influence of Temperature: Solubility may increase with higher temperatures in organic solvents, potentially benefiting from enhanced molecular motion.
  • pH Influence: The ionization state can affect solubility; careful consideration of pH may be necessary in specific applications.

In summary, the solubility profile of C18H22O2 emphasizes its preference for organic solvents, making it essential to choose the appropriate solvent for successful application and experimentation. As always, for practical applications, conducting empirical tests is advisable to determine the exact solubility behavior under specific conditions.

Interesting facts

Interesting Facts about 10,13-Dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione

This fascinating compound is a member of the steroid family and is particularly notable due to its structural complexity and potential bioactivity. Here are some intriguing aspects of this compound:

  • Biochemical Relevance: This compound showcases a unique arrangement of rings and substituents, which suggests important interactions with biological systems. Compounds like these often play roles in hormonal and metabolic activities within living organisms.
  • Cyclopenta[a]phenanthrene Core: The structure includes a cyclopenta[a]phenanthrene framework, renowned for its ability to mimic steroid hormones, making it a subject of interest in the fields of pharmacology and biochemistry.
  • Dimethyl Substitutions: The presence of dimethyl groups at the 10 and 13 positions could influence the compound's lipophilicity and receptor binding affinity, which is crucial for its biological activity.
  • Potential Applications: Research indicates that molecules with similar structures may exhibit anti-inflammatory, antitumor, or antiviral properties. This positions the compound as a promising candidate for further pharmacological studies.

In addition to its scientific implications, this compound exemplifies the beauty of organic chemistry, displaying how subtle changes in molecular structure can dramatically alter biological interactions. As quoted by chemists, "The devil is in the details," and in the world of chemical compounds, the intricacies of structure often determine function.

This compound is a reminder of the vast potential that lies within organic chemistry, inspiring continued research and discovery!

Synonyms
10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione
Androsta-1,17-dione
Androstra-1,17-dione
Androstane-1,17-dione
.DELTA.1,17-dione
CHEMBL8512
1,4-Androsten-3,17-dione
BDBM9954
SCHEMBL3758714
CHEBI:182567
NSC49080
CCG-52094
AKOS015962216
AC-16146
DB-057155
NS00008175
SR-01000641347
SR-01000641347-1
SR-01000641347-2
2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadeca-3,6-diene-5,14-dione