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Identification
Molecular formula
C25H25BrN3O3
CAS number
124080-16-6
IUPAC name
(10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinolin-9-yl)methyl 5-bromopyridine-3-carboxylate
State
State
The compound is typically found in a solid state at room temperature, reflecting its crystalline structure.
Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
438.39g/mol
Molar mass
438.3400g/mol
Density
1.3000g/cm3
Appearence
The compound is a crystalline solid. Its exact color and form may vary depending on purity and morphology.
Comment on solubility

Solubility of (10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinolin-9-yl)methyl 5-bromopyridine-3-carboxylate

The compound with the formula C25H25BrN3O3 presents some intriguing characteristics in terms of solubility. Understanding the solubility behavior of such complex organic molecules is essential for their application in various fields, including pharmacology and material science.

Key Points on Solubility:

  • Solvent Affinity: The solubility of this compound may be influenced by its functional groups, particularly the presence of a methoxy group and a bromine atom, which can enhance intermolecular interactions with polar solvents.
  • Polarity: Given its large and comparatively hydrophobic structure, it is likely to demonstrate limited solubility in water, favoring organic solvents such as ethanol or DMSO.
  • Temperature Effect: Like many organic compounds, increased temperature may improve its solubility by disrupting crystal lattice energy and enhancing molecular movement.
  • pH Dependency: The solubility might vary with pH, particularly in biological environments, where ionization of functional groups could alter solubility characteristics.

In summary, while precise solubility data for this specific compound may not be readily available, understanding the interplay of these factors can provide valuable insight into its solubility behavior. As always, experimental validation is critical for accurate characterization.

Interesting facts

Interesting Facts about (10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinolin-9-yl)methyl 5-bromopyridine-3-carboxylate

This intricate compound belongs to the class of indoloquinolines, which are known for their diverse biological activities. Compounds like this are particularly fascinating due to their potential in medicinal chemistry. Here are some interesting aspects to consider:

  • Structure Complexity: The compound features a multi-ring structure combining both indole and quinoline frameworks, which contributes to its unique chemical properties.
  • Biological Activity: The indoloquinoline core is associated with various pharmacological effects, including anti-cancer and anti-microbial activities, making compounds of this nature attractive in drug discovery.
  • Synthesis Challenges: The synthesis of such complex molecules can be quite challenging, often requiring multiple reaction steps and careful optimization of conditions.
  • Potential Applications: There's ongoing research on how derivatives of this compound might serve as therapeutic agents in treating diseases like cancer, due to the presence of both bromine and pyridine moieties, which can interact with biological targets.
  • Chemical Modifications: Substituents on the core structure can be varied to fine-tune the compound’s activity, “leading researchers to explore a broad library of derivatives.”

The exploration of compounds such as this one not only enriches the field of organic synthesis but also broadens our understanding of their pharmacological potential. Discoveries in this area illustrate the profound interplay between synthetic chemistry and biological inquiry.

Synonyms
(10-methoxy-1,6-dimethylergolin-8-yl)methyl 5-bromopyridine-3-carboxylate
Nicotergoline
Nargoline
Oprea1_110366
CHEMBL4744096
CHEBI:95219
DTXSID00860404
YSEXMKHXIOCEJA-UHFFFAOYSA-N
HMS3266B07
NSC150531
STL445693
AKOS040894269
DB-047284
L000717
BRD-A99721021-001-01-3
Q27167040
Ergoline-8.beta.-methanol,6-dimethyl-, 5-bromonicotinate (ester)
10-Methoxy-1,6-dimethylergoline-8.beta.-methanol 5-bromonicotinate ester
Ergoline-8-methanol,6-dimethyl-, (8.beta.)-, 5-bromo-3-pyridinecarboxylate ester
Ergoline-8-methanol,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8.beta.)-
5-bromo-3-pyridinecarboxylic acid (10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl)methyl ester
Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8.beta.)-
MNE