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Acridone

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Identification
Molecular formula
C13H9NO
CAS number
578-95-0
IUPAC name
10H-acridin-3-one
State
State

At room temperature, Acridone is a solid. It is often encountered as a crystalline powder.

Melting point (Celsius)
224.00
Melting point (Kelvin)
497.15
Boiling point (Celsius)
457.60
Boiling point (Kelvin)
730.75
General information
Molecular weight
195.22g/mol
Molar mass
195.2160g/mol
Density
1.3175g/cm3
Appearence

Acridone typically appears as yellow crystalline solid. It has a distinct, strong odor.

Comment on solubility

Solubility of 10H-acridin-3-one

10H-acridin-3-one, with the chemical formula C13H9NO, displays intriguing solubility characteristics that are worth noting.

  • Solvent Compatibility: This compound is typically soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). These solvents are often preferred due to their ability to effectively dissolve organic compounds.
  • Insolubility in Water: 10H-acridin-3-one is practically insoluble in water, which is common for many organic compounds, particularly those with larger hydrophobic regions.
  • Temperature Dependencies: Solubility may increase with temperature; thus, higher temperatures could enhance its solubilization in appropriate solvent mixtures.

In summary, the solubility profile of 10H-acridin-3-one is an essential consideration for applications such as pharmaceuticals and materials science. Its compatibility with organic solvents and limited aqueous solubility must be carefully managed in practical applications. Thus, one should consider these factors when working with this compound in laboratory settings.

Interesting facts

Interesting Facts about 10H-Acridin-3-one

10H-acridin-3-one is a fascinating compound in the realm of organic chemistry and has a rich history of applications and studies. Here are some engaging insights regarding this intriguing compound:

  • Dual Functionality: 10H-acridin-3-one acts as both a dye and a potential pharmacological agent. Its ability to serve multiple roles makes it a valuable molecule in various fields.
  • Intercalation Properties: This compound has the ability to intercalate into DNA, which suggests potential for use in cancer therapeutics. Its interaction with nucleic acids has been studied for developing effective treatments.
  • Natural Sources: Acridin derivatives are found in several natural products. For instance, they have been isolated from various plants and fungi, hinting at their ecological significance.
  • Mechanistic Studies: Scientists often perform detailed mechanistic studies involving 10H-acridin-3-one to understand its reactivity and interaction with biological molecules, opening up avenues for novel drug designs.
  • Historical Significance: The acridine scaffold has been utilized in the synthesis of several renowned pharmaceutical agents throughout history, including antiseptics and antimalarials.

In summary, the unique traits of 10H-acridin-3-one contribute to its reputation as an important compound in medicinal and synthetic chemistry. As you delve deeper into its properties and applications, you may find that its impact reaches far beyond initial expectations.