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Tacrolimus

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Identification
Molecular formula
C44H69NO12
CAS number
104987-11-3
IUPAC name
(10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one
State
State

The compound is a solid at room temperature, typically appearing as crystalline powder.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
562.00
Boiling point (Kelvin)
835.15
General information
Molecular weight
822.04g/mol
Molar mass
822.0420g/mol
Density
1.1500g/cm3
Appearence

The compound is a white to off-white crystalline powder.

Comment on solubility

Solubility of (10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one

The solubility of (10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one presents intriguing characteristics due to its complex structure. Understanding its solubility is crucial for potential applications in pharmaceuticals and chemical research. Here are some points to consider:

  • Polarity: The presence of nitrogen atoms in the scaffold can enhance the polarity of the compound, potentially affecting its solubility in various solvents.
  • Size and Structure: Its large, multi-cyclic structure might hinder solubility in polar solvents due to steric hindrance; however, it might exhibit better solubility in non-polar solvents.
  • Common Solvents: Compounds of similar frameworks often dissolve better in dimethyl sulfoxide (DMSO) or dimethylformamide (DMF), but less so in water.
  • Temperature Effects: Increasing temperature typically enhances solubility for many organic compounds, although specific behaviors can differ.

In summary, the solubility of (10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one may vary significantly based on its interactions with solvents, creating a fascinating area for further study. As one researcher noted, "Understanding the solubility profile of complex compounds can unlock new pathways in synthetic chemistry."

Interesting facts

Interesting Facts about (10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one

This fascinating compound belongs to a class of molecules that exhibit a unique tetracyclic structure. Its intriguing arrangement allows for a variety of interesting properties and potential applications in different scientific fields. Here are some key aspects to consider:

  • Structural Complexity: The compound features a highly complex tetracyclic framework, which is not only interesting from a synthetic perspective but also hints at unique interactions with biological systems.
  • Potential Pharmacological Applications: Due to its nitrogen-containing bicyclic structures, compounds like this one can exhibit interesting biological activities. Scientists are continually exploring their potential as pharmaceuticals.
  • Synthetic Challenges: The synthesis of such complex molecules often requires advanced techniques, showcasing the ingenuity of chemists. The formation of multiple rings often involves multi-step synthetic pathways and can be a topic of study in organic chemistry.
  • Conformational Studies: Structural isomerism is an essential topic in chemistry, and studying the different conformations of compounds like this can lead to insights into their reactivity and stability.
  • Role in Organic Synthesis: The compound's framework can serve as a valuable scaffold for synthesizing other intricate chemical structures, especially in the creation of drugs and agrochemicals.

As you delve deeper into the world of organic compounds, remember that understanding the structure-activity relationship of complex molecules like (10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one is crucial for developing new materials and therapeutic agents. The beauty of chemistry lies in how these intricate patterns and interactions lead to innovations in various scientific areas.

Synonyms
(10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4-dien-6-one
C10750
AC1L9DOW
Oprea1_709034
SCHEMBL257966
CHEMBL203399
AKOS024282715
NCGC00017377-02
NCGC00142555-01
Q27105771
7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, 1,3,4,6,7,13,14,14a-octahydro-, (14aR)-