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Flubromazepam

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Identification
Molecular formula
C19H18N2O
CAS number
2647-50-9
IUPAC name
11-[2-(diethylamino)ethyl]-5H-benzo[b][1,4]benzodiazepin-6-one
State
State

At room temperature, Flubromazepam exists as a solid. Its typical crystalline or powdered form is stable under standard atmospheric conditions. It is not volatile and remains in solid form unless elevated temperatures are applied.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
337.50
Boiling point (Kelvin)
610.65
General information
Molecular weight
290.37g/mol
Molar mass
0.0000g/mol
Density
1.3688g/cm3
Appearence

Flubromazepam is typically presented as a white or off-white crystalline powder. It may also appear as a solid form, such as crystals or a compacted powder, depending on its preparation and handling conditions. Its powdered form is fine and may clump slightly if exposed to ambient moisture due to its hygroscopic nature.

Comment on solubility

Solubility of 11-[2-(diethylamino)ethyl]-5H-benzob[1,4]benzodiazepin-6-one

The solubility of 11-[2-(diethylamino)ethyl]-5H-benzob[1,4]benzodiazepin-6-one in various solvents is an important aspect to consider for its applications in pharmaceuticals and chemical research. Understanding its solubility characteristics can provide valuable insights for formulation and delivery methods.

  • Generally, compounds with a complex molecular structure such as this one tend to exhibit varied solubility depending on the solvent.
  • It is expected to have good solubility in polar organic solvents due to the presence of the diethylamino group, which can interact favorably with polar environments.
  • However, its solubility in water might be limited, as many benzodiazepine derivatives display hydrophobic characteristics.
  • Factors influencing solubility include:
    • Temperature
    • pH of the solution
    • Presence of salts or co-solvents

In conclusion, while 11-[2-(diethylamino)ethyl]-5H-benzob[1,4]benzodiazepin-6-one may demonstrate favorable solubility in organic solvents, its aqueous solubility could pose challenges. Understanding these properties is crucial for its effective utilization in practical applications.

Interesting facts

Interesting Facts about 11-[2-(diethylamino)ethyl]-5H-benzo[b][1,4]benzodiazepin-6-one

This compound is a member of the benzodiazepine family, which is renowned for its diverse pharmacological properties. Benzodiazepines are most commonly known for their usage as anxiolytics and sedatives, but the intriguing aspects of this specific compound make it stand out even further.

Key Characteristics

  • Structure: The complex structure of this compound features a benzo[b][1,4]benzodiazepine framework, which is crucial for its biological activity. The unique arrangement of atoms allows for potential interactions with the central nervous system receptors.
  • Diethylamino Group: The presence of the diethylamino side chain suggests enhanced lipophilicity, potentially influencing the compound's ability to cross the blood-brain barrier.
  • Pharmacological Potential: Research indicates that derivatives of benzodiazepines can exhibit a range of effects, from anxiolytic to anticonvulsant properties. This opens doors for further investigation into its therapeutic uses.

Applications and Research

This compound could be explored in the following areas:

  • Anxiety Disorders: Given the benzodiazepine class's well-documented effects on anxiety, this compound might hold promise in developing new treatments.
  • Sleep Disorders: Its sedative properties can be of interest in addressing insomnia or other sleep-related issues.
  • Future Studies: Ongoing research into similar compounds is essential to understand their mechanism of action, therapeutic outcomes, and potential side effects.

Final Thoughts

In summary, 11-[2-(diethylamino)ethyl]-5H-benzo[b][1,4]benzodiazepin-6-one serves as a compelling example of the complexity and potential of benzodiazepine derivatives in medicinal chemistry. With ongoing advancements in research, compounds like this could lead to significant breakthroughs in understanding and treating various neurological conditions.

Synonyms
14870-41-8
BRN 0760069
11H-DIBENZO(b,e)(1,4)DIAZEPIN-11-ONE, 5,10-DIHYDRO-5-(2-(DIETHYLAMINO)ETHYL)-
DTXSID70164067
5-(2-(Diethylamino)ethyl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-one
5-[2-(Diethylamino)ethyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
DTXCID5086558
5-24-04-00111 (Beilstein Handbook Reference)
11-[2-(diethylamino)ethyl]-5H-benzo[b][1,4]benzodiazepin-6-one