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Dibenzazepinone derivative

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Identification
Molecular formula
C18H20N2O
CAS number
51297-49-3
IUPAC name
11-[3-(dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one
State
State

The compound is typically a solid at room temperature.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
270.37g/mol
Molar mass
270.3680g/mol
Density
1.2500g/cm3
Appearence

The compound is typically a crystalline solid that may appear white or off-white in color.

Comment on solubility

Solubility Insights for 11-[3-(dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one

The solubility of 11-[3-(dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one can be influenced by various factors, including its structure and functional groups. Understanding its solubility can aid in predicting its behavior in different environments. Here are some key points to consider:

  • Polarity: The presence of the dimethylamino group suggests potential for strong intermolecular interactions, especially in polar solvents. This may enhance its solubility in polar organic solvents.
  • Solvent Compatibility: Typically, compounds like this can exhibit better solubility in:
    1. Alcohols (e.g., ethanol)
    2. Aromatic hydrocarbons (e.g., toluene)
    3. Dimethyl sulfoxide (DMSO)
  • Temperature Dependence: As with many organic compounds, solubility can increase with temperature, which assists in dissolving higher concentrations.
  • pH Variation: The environment's pH can affect the ionization of the dimethylamino group, potentially altering solubility in aqueous solutions. Generally, a higher pH may enhance solubility in water by promoting ionization.

Overall, solubility characteristics are crucial for understanding how 11-[3-(dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one can be properly utilized in various applications, including pharmaceutical formulations or chemical reactions. Consult specific solubility data for precise information regarding particular solvents and environmental conditions.

Interesting facts

Interesting Facts about 11-[3-(Dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one

11-[3-(Dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one is a fascinating chemical compound known for its intriguing structure and potential applications. Here are some key points that make this compound noteworthy:

  • Complex Structure: This compound features a unique bicyclic system that includes a benzazepine core. The structural complexity contributes to its diverse pharmacological properties.
  • Psychoactive Potential: Due to the presence of the dimethylamino group, this compound is explored for its potential psychoactive effects, which have implications in neuroscience and mental health therapies.
  • Research Interest: Scientists are particularly interested in the molecule's behavior as a potential ligand to various receptors in the brain. This opens avenues for drug development targeting conditions like anxiety, depression, and even neurodegenerative diseases.
  • Multi-functional Groups: The dimethylamino group enhances the solubility and biological activity of the compound, making it a versatile candidate for various therapeutic applications.
  • Continued Exploration: Ongoing studies are aimed at understanding the compound's mechanism of action at the molecular level, shedding light on how it interacts with specific biological targets.

The study of 11-[3-(dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one not only highlights the importance of chemical structure in determining biological activity but also embodies the excitement of discovery within the field of medicinal chemistry. As researchers delve into its properties, they hope to unlock new treatments and enhance our understanding of the complex interplay between chemistry and biology.

Synonyms
Ketimipramine
Ketipramine
Ketimipramina
796-29-2
Ketimipraminum
U5C4H63K5U
DTXSID60229790
5-(3-(Dimethylamino)propyl)-5,11-dihydro-10H-dibenz(b,f)azepin-10-one
5-[3-(Dimethylamino)propyl]-5,11-dihydro-10H-dibenz[b,f]azepin-10-one
DTXCID10152281
1-ALPHA-4,5-ALPHA-H-TROPANIUM, 3-ALPHA-HYDROXY-8-(P-PHENYLPHENACYL)-, (-)-TROPATE
Ketimipramine [INN]
Ketimipraminum [INN-Latin]
UNII-U5C4H63K5U
Ketimipramina [INN-Spanish]
Ketoimipramine
imipramine ther
11-[3-(dimethylamino)propyl]-6H-benzo[b][1]benzazepin-5-one
10-Ketoimipramine
Ketimipramine Free Base
SCHEMBL1156090
CHEMBL2110856
SCHEMBL30801388
PXHIRIWYXDUSMR-UHFFFAOYSA-N
GP 35259
NS00124546
Q6395416
5-[3-(Dimethylamino)propyl]-5,11-dihydro-10H-dibenzo[b,f]azepin-10-one #