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Diclofenac

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Identification
Molecular formula
C9H8Cl2O2
CAS number
15307-79-6
IUPAC name
1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol
State
State

At room temperature, Diclofenac is a solid.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
296.24g/mol
Molar mass
296.2410g/mol
Density
1.4570g/cm3
Appearence

Diclofenac appears as a white or off-white crystalline powder. It is practically odorless and has a bitter taste.

Comment on solubility

Solubility of 1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol

The compound 1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol, with a complex structure containing both aromatic and aliphatic components, exhibits notable solubility characteristics that are essential for its application in various chemical processes.

In general, the solubility of a compound like this is influenced by several factors:

  • Polarity: The presence of the ethoxy group increases hydrophilicity, which may enhance solubility in polar solvents.
  • Aromatic Rings: The chlorophenyl groups tend to increase lipophilicity, indicating that this compound may be more soluble in organic solvents.
  • Hydrogen Bonding: The hydroxyl functional group can engage in hydrogen bonding, potentially improving its solubility in water to some extent.

As a result, 1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol is likely to be soluble in:

  • Common organic solvents such as ethanol, acetone, and dichloromethane.
  • Water, but to a limited degree, due to the competing effects of the hydrophilic and lipophilic groups.

Overall, the solubility of this compound is quite versatile, enabling it to be utilized effectively across different chemical environments. As with many compounds, conducting direct solubility experiments in the intended solvent system will provide the most accurate insights.

Interesting facts

Interesting Facts about 1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol

1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol is a fascinating compound with a unique structure that makes it stand out in the field of chemistry. Here are some key highlights:

  • Pharmaceutical Significance: This compound is studied for its potential applications in pharmaceuticals, particularly as an intermediate in the synthesis of various medicinal agents.
  • Chlorine Atoms: The presence of chlorophenyl groups enhances its biological activity, making it a subject of interest for researchers focusing on antimicrobial and anti-inflammatory properties.
  • Synthesis Routes: Various synthetic pathways have been explored to create this compound, including nucleophilic substitutions and reduction processes, showcasing the versatility of organic chemistry.
  • Applications Beyond Medicine: Beyond typical pharmaceutical applications, derivatives of this compound could find use in materials science, particularly in the development of polymers and coatings.
  • Structural Characteristics: The ethoxy group contributes to its solubility and reactivity, making it an intriguing subject for studies in organic synthesis.

In summary, 1,1-bis(4-chlorophenyl)-2-ethoxy-ethanol encompasses a wide range of chemical and biological properties, making it a valuable compound in both academic research and industrial applications. As with many compounds containing halogenated phenyl groups, understanding its behavior can lead to innovations in food, health, and technology.

Synonyms
ETOXINOL
Geigy 337
1,1-Bis(4-chlorophenyl)-2-ethoxyethanol
Ethoxymethylbis(p-chlorophenyl)carbinol
Ethoxymethyldichlorophenylcarbinol
1-Ethoxymethyl-1,1-bis(p-chlorophenyl)carbinol
G-23645
NSC 174203
UNII-LD999IE05Q
ENT 18595
BRN 2508265
LD999IE05Q
Ethoxymethyl-di-(p-chlorophenyl)carbinol
4,4'-Dichloro-alpha-(ethoxymethyl)benzhydrol
1-Ethoxymethyl-1,1-di-(p-chlorophenyl)carbinol
4,4'-Dichloro-.alpha.-(ethoxymethyl)benzhydrol
Ethoxymethyldi(p-chlorophenyl)carbinol
Benzhydrol, 4,4'-dichloro-alpha-(ethoxymethyl)-
NSC-174203
Benzhydrol, 4,4'-dichloro-.alpha.-(ethoxymethyl)-
Benzenemethanol, 4-chloro-.alpha.-(4-chlorophenyl)-.alpha.-(ethoxymethyl)-
1-Ethoxymethyl-1,1-di(p-chlorophenyl)carbinol
DTXSID90208871
4-06-00-06696 (Beilstein Handbook Reference)
Ethoxymethyldi(4-chlorophenyl)carbinol
Benzenemethanol, 4-chloro-alpha-(4-chlorophenyl)-alpha-(ethoxymethyl)-
DTXCID40131362
Benzenemethanol, 4-chloro-alpha-(4-chlorophenyl)-alpha-(ethoxymethyl)-(9CI)
cpzlrdxklhkmqx-uhfffaoysa-n
6012-83-5
SCHEMBL433468
WLN: GR DXQ1O2&R DG
Ethoxymethyldi(chlorophenyl)carbinol
NSC174203
DS-002733
Benzhydrol,4'-dichloro-.alpha.-(ethoxymethyl)-
Q27282930